Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Diana Retana"'
Autor:
Lucía Zhu, Diana Retana, Pedro García‐Gómez, Laura Álvaro‐Espinosa, Neibla Priego, Mariam Masmudi‐Martín, Natalia Yebra, Lauritz Miarka, Elena Hernández‐Encinas, Carmen Blanco‐Aparicio, Sonia Martínez, Cecilia Sobrino, Nuria Ajenjo, Maria‐Jesus Artiga, Eva Ortega‐Paino, Raúl Torres‐Ruiz, Sandra Rodríguez‐Perales, RENACER, Riccardo Soffietti, Luca Bertero, Paola Cassoni, Tobias Weiss, Javier Muñoz, Juan Manuel Sepúlveda, Pedro González‐León, Luis Jiménez‐Roldán, Luis Miguel Moreno, Olga Esteban, Ángel Pérez‐Núñez, Aurelio Hernández‐Laín, Oscar Toldos, Yolanda Ruano, Lucía Alcázar, Guillermo Blasco, José Fernández‐Alén, Eduardo Caleiras, Miguel Lafarga, Diego Megías, Osvaldo Graña‐Castro, Carolina Nör, Michael D Taylor, Leonie S Young, Damir Varešlija, Nicola Cosgrove, Fergus J Couch, Lorena Cussó, Manuel Desco, Silvana Mouron, Miguel Quintela‐Fandino, Michael Weller, Joaquín Pastor, Manuel Valiente
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 3, Pp n/a-n/a (2022)
Abstract We report a medium‐throughput drug‐screening platform (METPlatform) based on organotypic cultures that allows to evaluate inhibitors against metastases growing in situ. By applying this approach to the unmet clinical need of brain metast
Externí odkaz:
https://doaj.org/article/192ccb44b2e3449a849f6353de0e50dd
Autor:
Carlota A García-Domínguez, Natalia Martínez, Teresa Gragera, Andrea Pérez-Rodríguez, Diana Retana, Gonzalo León, Agustín Sánchez, José Luis Oliva, Dolores Pérez-Sala, José M Rojas
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16787 (2011)
Sprouty and Spred proteins have been widely implicated in the negative regulation of the fibroblast growth factor receptor-extracellular regulated kinase (ERK) pathway. In considering the functional role of these proteins, we explored their effects o
Externí odkaz:
https://doaj.org/article/48e19c28ab1c458eae1f03da80e9dcd9
Autor:
Juan José Garrido, Pablo Mendez, Michaël Russier, Diana Retana, Norah Boumedine-Guignon, Wei Zhang, Beatriz Achón, Dominique Debanne, Maria Ciorraga
Publikováno v:
Molecular Neurobiology
Molecular Neurobiology, 2021, ⟨10.1007/s12035-021-02531-6⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Neurobiology, Humana Press, 2021, ⟨10.1007/s12035-021-02531-6⟩
Molecular Neurobiology, 2021, ⟨10.1007/s12035-021-02531-6⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Neurobiology, Humana Press, 2021, ⟨10.1007/s12035-021-02531-6⟩
The axon initial segment (AIS) is essential for maintaining neuronal polarity, modulating protein transport into the axon, and action potential generation. These functions are supported by a distinctive actin and microtubule cytoskeleton that control
Autor:
Pedro García-Gómez, Diana Retana, Pablo Sanz-Martínez, Irene Salgado-Crespo, Carolina Hernández-Oliver, Maria Isabel García, Oliva Sánchez, Kevin Troulé-Lozano, Verona Villar-Cerviño, Miguel Lafarga-Coscojuela, Fátima Al-Shahrour, RENACER Red Nacional de Metástasis Cerebral, Manuel Valiente
Publikováno v:
Cancer Research. 83:3516-3516
The physical interaction between metastasis-initiating cells and the pre-existing capillary network (a process known as vascular co-option) is critical during the initial stages of multi-organ metastasis in cancer. As such, this process might provide
Autor:
Joaquín Pastor, Elena Hernández-Encinas, Angel Perez-Nuñez, Manuel Desco, Carolina Nor, Michael D. Taylor, Michael Weller, Eduardo Caleiras, Luca Bertero, Yolanda Ruano, Paola Cassoni, Sonia Sánchez Martínez, Diana Retana, Osvaldo Graña-Castro, Manuel Valiente, Lorena Cussó, Natalia Yebra, Aurelio Hernández-Laín, Javier Munoz, Lucía Zhu, Tobias Weiss, Carmen Blanco-Aparicio, Riccardo Soffietti, Diego Megías, Oscar Toldos, Lauritz Miarka, Juan Manuel Sepúlveda
Exclusion of brain metastases from clinical trials is a major cause of the limited therapeutic options for this growing population of cancer patients. Here, we report a medium-throughput drug-screening platform (METPlatform) based on organotypic cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac74e1595c29eb9c06e5fd20b1815c8f
https://doi.org/10.1101/2020.10.16.329243
https://doi.org/10.1101/2020.10.16.329243
Autor:
Paola Cassoni, Luca Bertero, Riccardo Soffietti, Michael D. Taylor, Tobias Weiss, Natalia Yebra, Sonia Martinez, Carmen Blanco-Aparicio, Javier Munoz, Lucía Zhu, Diana Retana, Eduardo Caleiras, Carolina Nör, Michael Weller, Joaquín Pastor, Angel Perez-Nuñez, Aurelio Hernández-Laín, Manuel Valiente, Oscar Toldos, Juan Manuel Sepúlveda
Publikováno v:
Neuro-oncology Advances
The diagnosis of brain metastasis involves high morbidity and mortality and remains an unmet clinical need in spite of being the most common tumor in the brain. Exclusion of these cancer patients from clinical trials is a major cause of their limited
Autor:
Vicente Soriano, Pilar Miralles, Jaime Cosín, Juan Carlos López, Juan Berenguer, María Ángeles Jiménez-Sousa, Norma Rallón, Daniel Pineda-Tenor, Diana Retana, Salvador Resino, María Guzmán-Fulgencio, Mónica García-Álvarez, José Miguel Benito
Publikováno v:
Journal of Clinical Virology. 65:62-67
Background Toll-like receptor-3 (TLR3) is a cellular receptor that may recognize double-stranded RNA (dsRNA) from viruses, resulting in production of proinflammatory cytokines and interferons, which are important for the adaptive immune response. Obj
Autor:
Beatriz Lara, Beatriz Martinez-Delgado, Nerea Matamala, Alvaro Otero, Taiomara Fernández-González, Antonio Muñoz-Callejas, Alpha Antitrypsin Deficiency Spanish Registry, Diana Retana, M. I. Martínez, Irene Vázquez
Publikováno v:
3.1 Molecular Pathology and Functional Genomics.
Alpha-1 antitrypsin deficiency (AATD) is a hereditary disorder caused by mutations in the SERPINA1 gene, and is characterized by lung emphysema and liver disease. AATD shows a high degree of phenotypic variability, which suggests that unknown genetic
Autor:
Dolores Pérez-Sala, Gonzalo Leon, Andrea Pérez-Rodríguez, José Luis Oliva, José M. Rojas, Á. Sánchez, Carlota A. García-Domínguez, Diana Retana, Natalia Martínez, Teresa Gragera
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16787 (2011)
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
PLoS ONE
Digital.CSIC. Repositorio Institucional del CSIC
instname
Repisalud
Instituto de Salud Carlos III (ISCIII)
Sprouty and Spred proteins have been widely implicated in the negative regulation of the fibroblast growth factor receptor-extracellular regulated kinase (ERK) pathway. In considering the functional role of these proteins, we explored their effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9756876aa0d1914cf48a5c79acc5d067
https://hdl.handle.net/20.500.12105/6842
https://hdl.handle.net/20.500.12105/6842