Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Diana R. Dou"'
Autor:
Zhipeng Lu, Jimmy K. Guo, Yuning Wei, Diana R. Dou, Brian Zarnegar, Qing Ma, Rui Li, Yang Zhao, Fan Liu, Hani Choudhry, Paul A. Khavari, Howard Y. Chang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The long noncoding RNA XIST plays a central role in sex-specific gene expression in humans by silencing one of two X chromosomes in female cells. Here the authors show that higher order secondary structure creates the modular domain structure of XIST
Externí odkaz:
https://doaj.org/article/ce192c166d4848879fbe0c187c228701
Autor:
Ava C Carter, Jin Xu, Meagan Y Nakamoto, Yuning Wei, Brian J Zarnegar, Quanming Shi, James P Broughton, Ryan C Ransom, Ankit Salhotra, Surya D Nagaraja, Rui Li, Diana R Dou, Kathryn E Yost, Seung-Woo Cho, Anil Mistry, Michael T Longaker, Paul A Khavari, Robert T Batey, Deborah S Wuttke, Howard Y Chang
Publikováno v:
eLife, Vol 9 (2020)
The Xist lncRNA mediates X chromosome inactivation (XCI). Here we show that Spen, an Xist-binding repressor protein essential for XCI , binds to ancient retroviral RNA, performing a surveillance role to recruit chromatin silencing machinery to these
Externí odkaz:
https://doaj.org/article/4ae4315c8e724765a92613e02ab27e83
Autor:
Brian T. Abe, Kathleen Aren, Lisa C. Zaba, Diana R. Dou, Yang Zhao, Lorinda Chung, Monique Hinchcliff, Mary Carns, Rui Li, Howard Y. Chang
Systemic sclerosis (SSc; scleroderma) is a poorly understood autoimmune rheumatic disease that primarily affects women. The clinical hallmark is hardening of the skin, but internal organ dysfunction is the leading cause of death. Diagnosis and treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac87190b4feccd4c4b91d3d6f40e30ed
https://doi.org/10.1101/2021.01.10.426131
https://doi.org/10.1101/2021.01.10.426131
Autor:
Paul A. Khavari, James P. Broughton, Surya Nagaraja, Meagan Y Nakamoto, Michael T. Longaker, Howard Y. Chang, Diana R. Dou, Kathryn E. Yost, Jin Xu, Ankit Salhotra, Yuning Wei, Seung Woo Cho, Ryan C. Ransom, Ava C. Carter, Rui Li, Anil Mistry, Quanming Shi, Deborah S. Wuttke, Robert T. Batey, Brian J. Zarnegar
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
The Xist lncRNA mediates X chromosome inactivation (XCI). Here we show that Spen, an Xist-binding repressor protein essential for XCI , binds to ancient retroviral RNA, performing a surveillance role to recruit chromatin silencing machinery to these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e83608da9ac3b9682ffd48751f824b
http://europepmc.org/articles/PMC7282817
http://europepmc.org/articles/PMC7282817
Autor:
James P. Broughton, Yuning Wei, Kathryn E. Yost, Brian J. Zarnegar, Paul A. Khavari, Surya Nagaraja, Quanming Shi, Anil Mistry, Deborah S. Wuttke, Ava C. Carter, Michael T. Longaker, Rui Li, Jin Xu, Ankit Salhotra, Howard Y. Chang, Ryan C. Ransom, Robert T. Batey, Meagan Y Nakamoto, Seung Woo Cho, Diana R. Dou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aacd56d83fb3d1697e9c4a801074b1eb
https://doi.org/10.7554/elife.54508.sa2
https://doi.org/10.7554/elife.54508.sa2
Autor:
Yuning Wei, Robert T. Batey, Howard Y. Chang, Deborah S. Wuttke, Meagan Y Nakamoto, James P. Broughton, Seung Woo Cho, Jin Xu, Diana R. Dou, Michael T. Longaker, Ryan C. Ransom, Rui Li, Ava C. Carter, Anil Mistry, Kathryn E. Yost, Ankit Salhotra, Surya Nagaraja, Quanming Shi
Dosage compensation between the sexes has emerged independently multiple times during evolution, often harnessing long noncoding RNAs (lncRNAs) to alter gene expression on the sex chromosomes. In eutherian mammals, X chromosome inactivation (XCI) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2178bd5f9c13e07d8f42803ea3fa47
Autor:
Fan Liu, Paul A. Khavari, Brian J. Zarnegar, Rui Li, Zhipeng Lu, Howard Y. Chang, Yuning Wei, Hani Choudhry, Yang Zhao, Qing Ma, Jimmy K. Guo, Diana R. Dou
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications
Long noncoding RNAs are thought to regulate gene expression by organizing protein complexes through unclear mechanisms. XIST controls the inactivation of an entire X chromosome in female placental mammals. Here we develop and integrate several orthog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a131e38e207c7711e391fe4f691177
https://doi.org/10.1101/837229
https://doi.org/10.1101/837229
Autor:
Louise E. Purton, Roger Emanuel Rönn, Vincenzo Calvanese, Hanna K. A. Mikkola, Diana R. Dou, Clea S. Grace
Publikováno v:
Experimental hematology. 65
Hematopoietic stem cells (HSCs) are multipotent cells responsible for the maintenance of the hematopoietic system throughout life. Dysregulation of the balance in HSC self-renewal, death, and differentiation can have serious consequences such as myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cc4c684fb7e94e0fd4b32ce6ababa3
https://pubmed.ncbi.nlm.nih.gov/29981365
https://pubmed.ncbi.nlm.nih.gov/29981365
Autor:
Diana R. Dou, Vincenzo Calvanese, Maria I. Sierra, Andrew T. Nguyen, Arazin Minasian, Pamela Saarikoski, Rajkumar Sasidharan, Christina M. Ramirez, Jerome A. Zack, Gay M. Crooks, Zoran Galic, Hanna K. A. Mikkola
Publikováno v:
Nature cell biology, vol 18, iss 6
Nature cell biology
Nature cell biology
Pluripotent stem cells (PSCs) may provide a potential source of haematopoietic stem/progenitor cells (HSPCs) for transplantation; however, unknown molecular barriers prevent the self-renewal of PSC-HSPCs. Using two-step differentiation, human embryon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a86bfafe146ff7652fa83537716fe7
https://escholarship.org/uc/item/7428v8mq
https://escholarship.org/uc/item/7428v8mq
Autor:
Triin Umbleja, Diana R. Dou, Marion G. Peters, Minhee Kang, Xiao Zhang, Roy M. Matining, Crystal H. Wang, Anu Osinusi, Shyam Kottilil, Valerianna Amorosa, Yu-Jin Lee, Tess Petersen
Publikováno v:
AIDS research and human retroviruses. 32(7)
A combination of nitazoxanide (NTZ), peginterferon (PegIFN), and ribavirin (RBV) may result in higher sustained virologic response (SVR) rates in hepatitis C virus (HCV) monoinfected patients. This study evaluated the effect of NTZ on interferon-stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321cc4e232759e4413749df9fb2a3beb
https://pubmed.ncbi.nlm.nih.gov/26974581
https://pubmed.ncbi.nlm.nih.gov/26974581