Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Diana Rädler"'
Autor:
Lucia Campos Carrascosa, Matthias Klein, Yohko Kitagawa, Christina Lückel, Federico Marini, Anika König, Anna Guralnik, Hartmann Raifer, Stefanie Hagner-Benes, Diana Rädler, Andreas Böck, Cholho Kang, Michael Lohoff, Holger Garn, Bianca Schaub, Friederike Berberich-Siebelt, Shimon Sakaguchi, Tobias Bopp, Magdalena Huber
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
IFN-γ signalling inhibits production of IL-9, the defining cytokine of the Th9 cell subset. Here the authors show that IFN-γ does this by driving IRF1 to compete with IRF4 forIl9promoter binding and skewing these cells towards a Th1 phenotype, an e
Externí odkaz:
https://doaj.org/article/13172fb84a7445059a0849047683d7fa
Autor:
Cholho Kang, Andreas Böck, Hartmann Raifer, Yohko Kitagawa, Magdalena Huber, Christina Lückel, Matthias Klein, Tobias Bopp, Friederike Berberich-Siebelt, Federico Marini, Holger Garn, Michael Lohoff, Diana Rädler, Shimon Sakaguchi, Stefanie Hagner-Benes, Lucia Campos Carrascosa, Bianca Schaub, Anna Guralnik, Anika König
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The T helper 9 (Th9) cell transcriptional network is formed by an equilibrium of signals induced by cytokines and antigen presentation. Here we show that, within this network, two interferon regulatory factors (IRF), IRF1 and IRF4, display opposing e