Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Diana Quon"'
Autor:
Darren H. Wong, Nicholas J. Gaspar, Gilbert O'Young, Gladys T. Muiru, Margaret Henson, Georgia Li, Ann M. Kapoun, Satyanarayana Medicherla, Diana Quon, Mamatha M. Reddy, Linda S. Higgins, Lingyun Li, Alison Murphy, Deborah Damm, Sarvajit Chakravarty
Publikováno v:
Molecular Pharmacology. 72:152-161
Transforming growth factor beta (TGFbeta) is a pleiotropic factor that regulates cell proliferation, angiogenesis, metastasis, and immune suppression. Dysregulation of the TGFbeta pathway in tumor cells often leads to resistance to the antiproliferat
Autor:
Thomas-Toan Tran, Andrew Lam, Gilbert O'Young, Alison Murphy, Diana Quon, Linda S. Higgins, Jing Ying Ma, Andrew A. Protter, Kimberly Munson, Debby Damm, Sundeep Dugar, Ying Wang, Sarvajit Chakravarty, Xiangde Liu, Stephen I. Rennard, Fu-Qiang Wen, Ann M. Kapoun, Yu-Wang Liu, Nicholas J. Gaspar
Publikováno v:
Molecular Pharmacology. 70:518-531
Transforming growth factor-beta (TGFbeta) is a major mediator of normal wound healing and of pathological conditions involving fibrosis, such as idiopathic pulmonary fibrosis. TGFbeta also stimulates the differentiation of myofibroblasts, a hallmark
Autor:
Andrew Lam, Faquan Liang, Ann M. Kapoun, George F. Schreiner, Diana Quon, Gilbert O'Young, Andrew A. Protter, Kimberly Munson, Deborah Damm, R. Tyler White
Publikováno v:
Circulation Research. 94:453-461
The natriuretic peptides, including human B-type natriuretic peptide (BNP), have been implicated in the regulation of cardiac remodeling. Because transforming growth factor-β (TGF-β) is associated with profibrotic processes in heart failure, we tes
Publikováno v:
Mammalian Genome. 4:211-219
The prenyltransferases are a class of enzymes involved in the synthesis of sterol and nonsterol isoprene compounds. We report here the chromosomal mapping of nine loci in the mouse that hybridize to the cDNA for the enzyme farnesyl pyrophosphate synt
Publikováno v:
Neuron. 8:145-158
Recombinant human ciliary neurotrophic factor (CNTF) was infused for 2 weeks into the lateral ventricle of fimbria-fornix transected adult rats, and its effects were compared with those of purified mouse nerve growth factor (NGF). We provide evidence
Autor:
Andy Protter, Sun J. Choi, Jing Y. Ma, Satyanarayana Medicherla, George F. Schreiner, Edwin Haghnazari, Linda S. Higgins, Tony A. Navas, G. David Roodman, Ann M. Kapoun, Mamatha Reddy, Diana Quon, Margaret Henson, Noriyoshi Kurihara, Gilbert O'Young, Debby Damm, Aaron N. Nguyen, Elizabeth G. Stebbins, Judy Anderson
Publikováno v:
Experimental cell research. 312(10)
The multiple myeloma (MM) bone marrow (BM) microenvironment plays a critical role in supporting tumor growth and survival as well as in promoting formation of osteolytic lesions. Recent results suggest that the p38 mitogen-activated protein kinase (M
Autor:
Debby Damm, Ann M. Kapoun, Tony A. Navas, Aaron N. Nguyen, Diana Quon, Linda S. Higgins, Gilbert O’ Young
Publikováno v:
Blood. 106:1569-1569
Multiple myeloma (MM) is a plasma cell cancer characterized by the accumulation and clonal expansion of malignant cells in the bone marrow (BM). Recent findings indicate that adhesion of MM cells to BM stromal cells (BMSCs) protects MM cells from dru
Autor:
Andrew Lam, Debby Damm, Diana Quon, Gilbert O'Young, Andrew A. Protter, Faquan Liang, Ty White, Ann M. Kapoun
Publikováno v:
Journal of Cardiac Failure. 9:S67
Proteomics Approach Detects Changes in Metabolic, Functional, and Structural Proteins During In Vivo Ischemia-Reperfusion and AT1 Receptor Blockade in the Dog Grzegorz Sawicki, Vijayan Menon, Bodh I. Jugdutt1,3—Medicine, Division of Cardiology, Uni
Autor:
Diana Quon, Argiris Efstratiadis, Catherine O'Connell, Ross C. Hardison, Elizabeth Lacy, Tom Maniatis, Gek Kee Sim, Joyce Lauer
Publikováno v:
Cell. 15:687-701
We present a procedure for eucaryotic structural gene isolation which involves the construction and screening of cloned libraries of genomic DNA. Large random DNA fragments are joined to phage lambda vectors by using synthetic DNA linkers. The recomb
Publikováno v:
Cell. 18(4)
Four different regions of rabbit beta-like globin gene sequences designated beta 1, beta 2, beta 3 and beta 4 were identified in a set of clones isolated from a bacteriophage lambda library of chromosomal DNA fragments (Maniatis et al., 1978). Restri