Hippocampal sclerosis of aging at post-mortem is evident on MRI more than a decade prior

Autor: Diana Ortega-Cruz, Juan Eugenio Iglesias, Alberto Rabano, Bryan Strange

Publikováno v: bioRxiv

INTRODUCTIONHippocampal sclerosis of aging (HS) is an important component of combined dementia neuropathology. However, the temporal evolution of its histologically-defined features is unknown. We investigated pre-mortem longitudinal hippocampal atro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364d5475e269fed14c6e7169f9bc517b
https://doi.org/10.1101/2023.03.08.531683

A novel histological staging of hippocampal sclerosis that is evident in grey matter lossin vivo

Autor: Diana Ortega-Cruz, Alicia Uceda-Heras, Juan Eugenio Iglesias, María Ascensión Zea-Sevilla, Bryan Strange, Alberto Rabano

INTRODUCTIONHippocampal sclerosis of aging (HS) is defined by end-stage histological findings, strongly associated with limbic-predominant age-related TDP-43 encephalopathy (LATE). We aimed to characterize features of early HS to refine the understan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dca177f59765d849998036f430abeb33
https://doi.org/10.1101/2022.12.13.520094

Disruption of Exocytosis in Sympathoadrenal Chromaffin Cells from Mouse Models of Neurodegenerative Diseases

Autor: Antonio M. G. de Diego, Antonio G. García, Diana Ortega-Cruz

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 6, p 1946 (2020)
Biblos-e Archivo. Repositorio Institucional de la UAM
Universidad Camilo José Cela (UCJC)
International Journal of Molecular Sciences
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid

Synaptic disruption and altered neurotransmitter release occurs in the brains of patients and in murine models of neurodegenerative diseases (NDDs). During the last few years, evidence has accumulated suggesting that the sympathoadrenal axis is also

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6a9aaa99c112dd535329bf436dd739
https://www.mdpi.com/1422-0067/21/6/1946