Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Diana O. Treaba"'
Autor:
Andrew Hsu, Kelsey E. Huntington, Andre De Souza, Lanlan Zhou, Adam J. Olszewski, Nirav P. Makwana, Diana O. Treaba, Ludimila Cavalcante, Francis J. Giles, Howard Safran, Wafik S. El-Deiry, Benedito A. Carneiro
Publikováno v:
Cancer Biology & Therapy, Vol 23, Iss 1, Pp 417-423 (2022)
GSK-3β is a serine/threonine kinase implicated in tumorigenesis and chemotherapy resistance. GSK-3β blockade downregulates the NF-κB pathway, modulates immune cell PD-1 and tumor cell PD-L1 expression, and increases CD8 + T cell and NK cell functi
Externí odkaz:
https://doaj.org/article/92cb5ee1490243b8bd245afdd67c0799
Autor:
Anna Chorzalska, Nagib Ahsan, R. Shyama Prasad Rao, Karim Roder, Xiaoqing Yu, John Morgan, Alexander Tepper, Steven Hines, Peng Zhang, Diana O. Treaba, Ting C. Zhao, Adam J. Olszewski, John L. Reagan, Olin Liang, Philip A. Gruppuso, Patrycja M. Dubielecka
Publikováno v:
Molecular Oncology, Vol 12, Iss 5, Pp 630-647 (2018)
The introduction of tyrosine kinase inhibitors (TKI) has transformed chronic myeloid leukemia (CML) into a chronic disease with long‐term survival exceeding 85%. However, resistance of CML stem cells to TKI may contribute to the 50% relapse rate ob
Externí odkaz:
https://doaj.org/article/61e7c5610dee4650acd0483ee9489b8a
Autor:
Diana O. Treaba, MD, Allison Chen, Chad Ellermeier, MD, Bradley DeNardo, MD, Rachel Altura, MD
Publikováno v:
Human Pathology: Case Reports, Vol 6, Iss C, Pp 1-7 (2016)
B-lymphoblastic leukemia is a clonal hematopoietic disorder of precursors B-lymphoblasts being most frequently encountered in children. Expression of CD19, a pan B-cell marker is noted in the majority of the cases with lack of CD19 expression being e
Externí odkaz:
https://doaj.org/article/cc7cb5797ce348d7a1b88181b0967198
Publikováno v:
Case Reports in Hematology, Vol 2017 (2017)
Hemoglobin (Hb) Sherwood Forest is a rare high-affinity hemoglobin first described in 1977, arising from an Arg to Thr substitution at codon 104 of the beta chain. This hemoglobin variant has been identified in few individuals and has been associated
Externí odkaz:
https://doaj.org/article/560bb57e779d42268fdfa2e0f6899692
Autor:
Fatima A. Aldarweesh, Diana O. Treaba
Publikováno v:
Case Reports in Hematology, Vol 2017 (2017)
An elderly woman with a complex medical history presented with a left forearm mass that slowly developed for several months. The excisional biopsy of this skin mass was remarkable for involvement by a follicle centre cell derived lymphoma with a nodu
Externí odkaz:
https://doaj.org/article/85f6b6483bb045f8ba8e514179c7c00c
Publikováno v:
Case Reports in Hematology, Vol 2016 (2016)
TAFRO syndrome is a rare constellation of symptoms: thrombocytopenia, anasarca, reticulin fibrosis of the bone marrow, renal dysfunction, and organomegaly. Its pathogenesis involves an excessive and inappropriate cytokine storm, most notably from IL-
Externí odkaz:
https://doaj.org/article/7c88b15c0b1e4336a394a62661e9b13f
Autor:
Diana O. Treaba, Salwa Khedr, Shamlal Mangray, Cynthia Jackson, Jorge J. Castillo, Eric S. Winer
Publikováno v:
Case Reports in Hematology, Vol 2012 (2012)
Primary myelofibrosis (formerly known as chronic idiopathic myelofibrosis), has the lowest incidence amongst the chronic myeloproliferative neoplasms and is characterized by a rather short median survival and a risk of progression to acute myeloid le
Externí odkaz:
https://doaj.org/article/cebd3e0d48a54a73b78ea80a662dc8fd
Autor:
Anna D Chorzalska, John Morgan, Diana O Treaba, Damali Simon-Ponte, Omonike Oyelola, John L Reagan, Patrycja M Dubielecka
Publikováno v:
Blood. 140:5880-5882
Autor:
Andrew R. Hsu, Pamela C Egan, Diana O. Treaba, Max Petersen, James N. Butera, Rabin Niroula, Adam J. Olszewski, Anna Chorzalska, Patrycja M. Dubielecka, John L. Reagan, Thomas A Ollila, Adam Zayac, John Vatkevich, Jordan Robison, Ilyas Sahin, Chelsea D. Mullins, Habibe Kurt, Allison P. Jacob
Publikováno v:
Blood Advances
Key Points The NGS-MRD assay detected clonotypic DNA in 100% of CSF samples from patients who had lymphoma with parenchymal CNS involvement.Clonotypic DNA in CSF was present in 36% of newly diagnosed aggressive lymphomas and was associated with a 29%
Autor:
Diana O. Treaba, Dennis M. Bonal, Anna Chorzalska, Mireia Castillo‐Martin, Alissa Oakes, Makayla Pardo, Max Petersen, Christoph Schorl, Kelsey Hopkins, Dean Melcher, Ting C. Zhao, Olin Liang, Eui‐Young So, John Reagan, Adam J. Olszewski, James Butera, Douglas C. Anthony, Peter Rintels, Peter Quesenberry, Patrycja M. Dubielecka
Publikováno v:
British journal of haematologyREFERENCES.
While the bone marrow (BM) microenvironment is significantly remodelled in acute myeloid leukaemia (AML), molecular insight into AML-specific alterations in the microenvironment has been historically limited by the analysis of liquid marrow aspirates