Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Diana O. Alieksieieva"'
Autor:
Olena V. Savych, Anastasia V. Gryniukova, Diana O. Alieksieieva, Igor M. Dziuba, Petro O. Borysko, Dmytro V. Dudenko, Volodymyr S. Brovarets, Yurii S. Moroz
Publikováno v:
Журнал органічної та фармацевтичної хімії, Vol 19, Iss 4, Pp 3-11 (2021)
Aim. To demonstrate the advantages of large-scale virtual libraries generated using chemical protocols previously validated in primary steps of the drug discovery process. Results and discussion. Two validated parallel chemistry protocols reported e
Externí odkaz:
https://doaj.org/article/88cc6ab66db446b0aa20dc242b95d679
Autor:
Alexey V. Rayevsky, Andrii S. Poturai, Iryna O. Kravets, Alexander E. Pashenko, Tatiana A. Borisova, Ganna M. Tolstanova, Dmitriy M. Volochnyuk, Petro O. Borysko, Olga B. Vadzyuk, Diana O. Alieksieieva, Yuliana Zabolotna, Olga Klimchuk, Dragos Horvath, Gilles Marcou, Sergey V. Ryabukhin, Alexandre Varnek
Publikováno v:
Molecules, Vol 27, Iss 17, p 5400 (2022)
New models for ACE2 receptor binding, based on QSAR and docking algorithms were developed, using XRD structural data and ChEMBL 26 database hits as training sets. The selectivity of the potential ACE2-binding ligands towards Neprilysin (NEP) and ACE
Externí odkaz:
https://doaj.org/article/178e51ad7468417082ac12b519f61623