Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Diana Mendus"'
1
Akademický článek
Diphenhydramine increases the therapeutic window for platinum drugs by simultaneously sensitizing tumor cells and protecting normal cells
Autor: Margarita Melnikova, Ulrike Sophie Wauer, Diana Mendus, Ralf Axel Hilger, Trudy G. Oliver, Kim Mercer, Björn Oliver Gohlke, Kati Erdmann, Dieter Niederacher, Hans Neubauer, Paul Buderath, Pauline Wimberger, Jan Dominik Kuhlmann, Jürgen Thomale
Publikováno v: Molecular Oncology, Vol 14, Iss 4, Pp 686-703 (2020)
Platinum‐based compounds remain a well‐established chemotherapy for cancer treatment despite their adverse effects which substantially restrict the therapeutic windows of the drugs. Both the cell type‐specific toxicity and the clinical responsi
Externí odkaz: https://doaj.org/article/c92a25a31abc4582925f02044ae84d0e
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2
Akademický článek
Fast progression in non–small cell lung cancer: results from the randomized phase III OAK study evaluating second-line atezolizumab versus docetaxel
Autor: Julien Mazières, Solange Peters, Andrés Cardona, Martin Reck, David Gandara, Denis Moro-Sibilot, Shirish Gadgeel, Stefanie Morris, Diana Mendus, Marcus Ballinger, Achim Rittmeyer
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Treatment-induced accelerated tumor growth is a progression pattern reported with immune checkpoint inhibitors that has never been evaluated in randomized phase III studies because it requires two pretreatment scans. This study aimed to de
Externí odkaz: https://doaj.org/article/083737184a6d4a08bbdbf8e494bd6434
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3
Akademický článek
A lack of immune system genes causes loss in high frequency hearing but does not disrupt cochlear synapse maturation in mice.
Autor: Melissa A Calton, Dasom Lee, Srividya Sundaresan, Diana Mendus, Rose Leu, Felix Wangsawihardja, Kenneth R Johnson, Mirna Mustapha
Publikováno v: PLoS ONE, Vol 9, Iss 5, p e94549 (2014)
Early cochlear development is marked by an exuberant outgrowth of neurites that innervate multiple targets. The establishment of mature cochlear neural circuits is, however, dependent on the pruning of inappropriate axons and synaptic connections. Su
Externí odkaz: https://doaj.org/article/f56dd616e6354a47b15481614e9782d9
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4
Fast progression in non–small cell lung cancer: results from the randomized phase III OAK study evaluating second-line atezolizumab versus docetaxel
Autor: David R. Gandara, S. Morris, A. Cardona, Julien Mazieres, Martin Reck, Marcus Ballinger, Diana Mendus, Denis Moro-Sibilot, Shirish M. Gadgeel, Achim Rittmeyer, Solange Peters
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Journal for immunotherapy of cancer, vol 9, iss 3
Journal for Immunotherapy of Cancer
BackgroundTreatment-induced accelerated tumor growth is a progression pattern reported with immune checkpoint inhibitors that has never been evaluated in randomized phase III studies because it requires two pretreatment scans. This study aimed to dev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696b1a80684149be9f3f8370b637920a
https://jitc.bmj.com/content/9/3/e001882.full
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5
Response to Letter to the Editor
Autor: Makoto Nishio, Diana Mendus, Lijia Wang, Mark A. Socinski
Publikováno v: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 16(5)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65375a2687202433199bebb8011b7c7d
https://pubmed.ncbi.nlm.nih.gov/33896575
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6
Atezolizumab Plus Chemotherapy for First-Line Treatment of Nonsquamous NSCLC: Results From the Randomized Phase 3 IMpower132 Trial
Autor: Tien Hoang, Silvia Novello, Lijia Wang, Zsuzsanna Szalai, Grigoriy Ursol, Francisco Orlandi, Diana Mendus, Jerome H. Goldschmidt, See Phan, Manuel Cobo, Mark McCleland, Howard Jack West, Simon Ball, Fabrice Barlesi, X. Wen, Mark A. Socinski, Rachel E. Sanborn, Makoto Nishio, Rodolfo Bordoni, Pascale Dubray Longeras
Publikováno v: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 16(4)
We report the final results of the phase 3 IMpower132 study evaluating atezolizumab plus carboplatin or cisplatin plus pemetrexed (APP) in patients with nonsquamous NSCLC.Chemotherapy-naive patients with stage IV nonsquamous NSCLC without sensitizing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b9d6c61a3c4ec6d4345253c2b081fa
https://pubmed.ncbi.nlm.nih.gov/33896576
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8
Increased sensitivity to kindling in mice lacking TSP1
Autor: Mirna Mustapha, Brenda E. Porter, Diana Mendus, Elyse K. Rankin-Gee
Publikováno v: Neuroscience. 305:302-308
The development of a hyperexcitable neuronal network is thought to be a critical event in epilepsy. Thrombospondins (TSPs) regulate synaptogenesis by binding the neuronal α2δ subunit of the voltage-gated calcium channel. TSPs regulate synapse forma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e420aeb7b2a9207911e57fbf10a8fd
https://doi.org/10.1016/j.neuroscience.2015.07.075
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