Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Diana Martik"'
Autor:
Leah Cosgrove, Timothy E. Adams, Yan Huang, Greg Conley, Douglas Rank, Dina Wassaf, Diana Martik, Kris Kopacz, Niksa Kastrapeli, Gemma V. Brierley, Ilka Priebe, Tram Phan, Patricia A. Pilling, Janet Newman, Thomas S. Peat, Xiaowen Xiao, Olan Dolezal, John D. Bentley, Lindsay G. Sparrow, Qing Chang, Edward H. Cohen, Daniel T. Dransfield
Supplementary Table from A Human Monoclonal Antibody against Insulin-Like Growth Factor-II Blocks the Growth of Human Hepatocellular Carcinoma Cell Lines In vitro and In vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6220c43728ee158f1e4761b040126ec5
https://doi.org/10.1158/1535-7163.22485011
https://doi.org/10.1158/1535-7163.22485011
Autor:
Leah Cosgrove, Timothy E. Adams, Yan Huang, Greg Conley, Douglas Rank, Dina Wassaf, Diana Martik, Kris Kopacz, Niksa Kastrapeli, Gemma V. Brierley, Ilka Priebe, Tram Phan, Patricia A. Pilling, Janet Newman, Thomas S. Peat, Xiaowen Xiao, Olan Dolezal, John D. Bentley, Lindsay G. Sparrow, Qing Chang, Edward H. Cohen, Daniel T. Dransfield
Elevated expression of insulin-like growth factor-II (IGF-II) is frequently observed in a variety of human malignancies, including breast, colon, and liver cancer. As IGF-II can deliver a mitogenic signal through both IGF-IR and an alternately splice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9990fdfadc29b2b4226f389d7d1c4acb
https://doi.org/10.1158/1535-7163.c.6531725
https://doi.org/10.1158/1535-7163.c.6531725
Autor:
Jill Whitley, Christopher Zwolinski, Christian Denis, Maureen Maughan, Leonie Hayles, David Clarke, Meghan Snare, Hong Liao, Sean Chiou, Tina Marmura, Holly Zoeller, Ben Hudson, John Peart, Monica Johnson, Amelia Karlsson, Yunfei Wang, Cynthia Nagle, Cherell Harris, Daniel Tonkin, Stephanie Fraser, Lieza Capiz, Christina L. Zeno, Yvonne Meli, Diana Martik, Daniel A. Ozaki, Amy Caparoni, Jason E. Dickens, Drew Weissman, Kevin O. Saunders, Barton F. Haynes, Gregory D. Sempowski, Thomas N. Denny, Matthew R. Johnson
Publikováno v:
Translational Research
The remarkable success of SARS CoV-2 mRNA-based vaccines and the ensuing interest in mRNA vaccines and therapeutics have highlighted the need for a scalable clinical-enabling manufacturing process to produce such products, and robust analytical metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299d585ffa687863b8792761c10df5ad
http://europepmc.org/articles/PMC8641981
http://europepmc.org/articles/PMC8641981
Autor:
Christopher Barbosa, Amanda Newman, Sravani Venkatayogi, Shi-Mao Xia, Rory Henderson, Wilton B. Williams, Qifeng Han, Barton F. Haynes, Robert J. Edwards, Robert Parks, Kevin O. Saunders, Kevin Wiehe, Mattia Bonsignori, Katayoun Mansouri, Norbert Pardi, Xiaozhi Lu, David C. Montefiori, Tyler Evangelous, Zekun Mu, Wes Rountree, Diana Martik, Yunfei Wang, Drew Weissman, Derek W. Cain, Ying Tam, S. Munir Alam
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
SUMMARYThe success of nucleoside-modified mRNAs in lipid nanoparticles (mRNA-LNP) as COVID-19 vaccines heralded a new era of vaccine development. For HIV-1, multivalent envelope (Env) trimer protein nanoparticles are superior immunogens compared to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e41b1f59f8d8926f0862f1c8d12ac5
https://doi.org/10.1101/2021.08.09.455714
https://doi.org/10.1101/2021.08.09.455714
Autor:
Zekun Mu, Kevin Wiehe, Kevin O. Saunders, Rory Henderson, Derek W. Cain, Robert Parks, Diana Martik, Katayoun Mansouri, Robert J. Edwards, Amanda Newman, Xiaozhi Lu, Shi-Mao Xia, Amanda Eaton, Mattia Bonsignori, David Montefiori, Qifeng Han, Sravani Venkatayogi, Tyler Evangelous, Yunfei Wang, Wes Rountree, Bette Korber, Kshitij Wagh, Ying Tam, Christopher Barbosa, S. Munir Alam, Wilton B. Williams, Ming Tian, Frederick W. Alt, Norbert Pardi, Drew Weissman, Barton F. Haynes
Publikováno v:
Cell reports. 38(11)
The success of nucleoside-modified mRNAs in lipid nanoparticles (mRNA-LNP) as COVID-19 vaccines heralded a new era of vaccine development. For HIV-1, multivalent envelope (Env) trimer protein nanoparticles are superior immunogens compared with trimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7e5b97e0ead1c16345c14e28eb03d1
https://pubmed.ncbi.nlm.nih.gov/35294883
https://pubmed.ncbi.nlm.nih.gov/35294883
Autor:
Allison P. Lindberg, Jie Chen, Jan Abendroth, Robert Charles Ladner, Thomas E. Edwards, Diana Martik, Mike DiLeo, Ryan Faucette, Andrew E. Nixon, Daniel J. Sexton, Shauna Mason, Jon A. Kenniston, Burt Adelman, Stephen R. Comeau, Janja Cosic, Niksa Kastrapeli, Christopher Tenhoor, Gregory P. Conley, Malini Viswanathan, Petr Kuzmic, Kris Kopacz
Publikováno v:
The Journal of Biological Chemistry
Background: Unregulated plasma kallikrein proteolytic activity can result from C1-inhibitor deficiency, causing excessive and potentially fatal edema. Results: The antibody DX-2930 potently and specifically inhibits plasma kallikrein and exhibits a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0dfd0c35b9bdf7cd1872a9cb611d4d4
http://europepmc.org/articles/PMC4156074
http://europepmc.org/articles/PMC4156074
Discovery and characterization of human antibody inhibitors of pregnancy-associated plasma protein-A
Autor:
Andrew E. Nixon, Diana Martik, Gary J. Bassill, Qi-Long Wu, Andrew N. Macintyre, Gary L. McNeil, Shannon Hogan, Daniel J. Sexton, Ting Chen, Csaba Pazmany, Greg Conley
Publikováno v:
bchm. 388:507-512
Pregnancy-associated plasma protein-A (PAPP-A) is a metalloprotease that cleaves insulin-like growth factor-binding proteins (IGFBPs) to release bioactive levels of free insulin-like growth factor. Specific and potent inhibitors of PAPP-A may further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e864fef5fc1dcc99902e2a1d9da1ba
https://doi.org/10.1515/bc.2007.058
https://doi.org/10.1515/bc.2007.058
Autor:
Jie Chen, Dina Wassaf, Malini Viswanathan, Diana Martik, Clive R. Wood, Chris TenHoor, Andrew E. Nixon, Joseph C. Biedenkapp, Daniel J. Sexton, Jennifer A. Dumont, Adam R. Mezo, Arumugam Muruganandam, Alan J. Bitonti
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 6 (2015)
Frontiers in Immunology, Vol 6 (2015)
The therapeutic management of antibody mediated autoimmune disease typically involves immunosuppressant and immunomodulatory strategies. However, perturbing the fundamental role of the neonatal Fc receptor (FcRn) in salvaging IgG from lysosomal degra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fdfc63ac3b5db58b466204f898d483
http://europepmc.org/articles/PMC4407741
http://europepmc.org/articles/PMC4407741
Publikováno v:
Journal of Biological Chemistry. 273:32055-32062
ATP hydrolysis by bacterial and eukaryotic MutS activities is required for their function in mismatch correction, and two different models for the role of ATP in MutS function have been proposed. In the translocation model, based on study of bacteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7330f46614b342bca914751b844cbfd2
https://doi.org/10.1074/jbc.273.48.32055
https://doi.org/10.1074/jbc.273.48.32055
Autor:
Qing Chang, Greg Conley, Niksa Kastrapeli, Thomas S. Peat, Leah J. Cosgrove, Olan Dolezal, John D. Bentley, Diana Martik, Xiaowen Xiao, Dina Wassaf, Janet Newman, Edward H. Cohen, Kris Kopacz, Gemma V. Brierley, Douglas Rank, Patricia A. Pilling, Ilka Priebe, Daniel T. Dransfield, Yan Huang, Lindsay G. Sparrow, Timothy E. Adams, Tram Phan
Publikováno v:
Molecular cancer therapeutics. 9(6)
Elevated expression of insulin-like growth factor-II (IGF-II) is frequently observed in a variety of human malignancies, including breast, colon, and liver cancer. As IGF-II can deliver a mitogenic signal through both IGF-IR and an alternately splice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df16d670ad4ca6da9f8e46a4792bc59d
https://pubmed.ncbi.nlm.nih.gov/20515953
https://pubmed.ncbi.nlm.nih.gov/20515953