Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Diana Mahdessian"'
Autor:
Lovisa Stenström, Diana Mahdessian, Christian Gnann, Anthony J Cesnik, Wei Ouyang, Manuel D Leonetti, Mathias Uhlén, Sara Cuylen‐Haering, Peter J Thul, Emma Lundberg
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 8, Pp 1-16 (2020)
Abstract The nucleolus is essential for ribosome biogenesis and is involved in many other cellular functions. We performed a systematic spatiotemporal dissection of the human nucleolar proteome using confocal microscopy. In total, 1,318 nucleolar pro
Externí odkaz:
https://doaj.org/article/cbf6f48dc6aa4e2ab84c21448c6a9ce1
Autor:
Johan Boström, Zuzana Sramkova, Alena Salašová, Helena Johard, Diana Mahdessian, Radek Fedr, Carolyn Marks, Jiřina Medalová, Karel Souček, Emma Lundberg, Sten Linnarsson, Vítězslav Bryja, Petra Sekyrova, Mikael Altun, Michael Andäng
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188772 (2017)
The cell cycle coordinates core functions such as replication and cell division. However, cell-cycle-regulated transcription in the control of non-core functions, such as cell identity maintenance through specific transcription factors (TFs) and sign
Externí odkaz:
https://doaj.org/article/cfa45d0d21e04a95bc8bf6de327dd273
Autor:
Trang Le, Casper F. Winsnes, Ulrika Axelsson, Hao Xu, Jayasankar Mohanakrishnan Kaimal, Diana Mahdessian, Shubin Dai, Ilya S. Makarov, Vladislav Ostankovich, Yang Xu, Eric Benhamou, Christof Henkel, Roman A. Solovyev, Nikola Banić, Vito Bošnjak, Ana Bošnjak, Andrija Miličević, Wei Ouyang, Emma Lundberg
Publikováno v:
Nature Methods. 19:1221-1229
While spatial proteomics by fluorescence imaging has quickly become an essential discovery tool for researchers, fast and scalable methods to classify and embed single-cell protein distributions in such images are lacking. Here, we present the design
Autor:
Diana Mahdessian, Fredrik Pontén, Mathias Uhlén, Manuel D. Leonetti, Fredric Johansson, Anna Bäckström, Christian Gnann, Frida Danielsson, Emma Lundberg, Lovisa Stenström, Peter Thul, Adil Mardinoglu, Nathan H. Cho, Cheng Zhang, Rutger Shutten, Devin P. Sullivan, Charlotte Stadler, Oana Carja, Trang Le, Ulrika Axelsson, Cecilia Lindskog, Anthony J. Cesnik, Muhammad Arif, Burcu Ayoglu
Publikováno v:
Nature. 590:649-654
The cell cycle, over which cells grow and divide, is a fundamental process of life. Its dysregulation has devastating consequences, including cancer1-3. The cell cycle is driven by precise regulation of proteins in time and space, which creates varia
Autor:
Diana Mahdessian, Anthony J. Cesnik, Christian Gnann, Frida Danielsson, Lovisa Stenström, Muhammad Arif, Cheng Zhang, Trang Le, Fredric Johansson, Rutger Schutten, Anna Bäckström, Ulrika Axelsson, Peter Thul, Nathan H. Cho, Oana Carja, Mathias Uhlén, Adil Mardinoglu, Charlotte Stadler, Cecilia Lindskog, Burcu Ayoglu, Manuel D. Leonetti, Fredrik Pontén, Devin P. Sullivan, Emma Lundberg
Publikováno v:
Nature. 608:E32-E32
Autor:
Josie A. Christopher, Charlotte Stadler, Claire E. Martin, Marcel Morgenstern, Yanbo Pan, Cora N. Betsinger, David G. Rattray, Diana Mahdessian, Anne-Claude Gingras, Bettina Warscheid, Janne Lehtiö, Ileana M. Cristea, Leonard J. Foster, Andrew Emili, Kathryn S. Lilley
Publikováno v:
Nature Reviews Methods Primers
Nat Rev Methods Primers
Nat Rev Methods Primers
The eukaryotic cell is compartmentalized into subcellular niches, including membrane-bound and membrane-less organelles. Proteins localize to these niches to fulfil their function, enabling discreet biological processes to occur in synchrony. Dynamic
Autor:
Frida Danielsson, Emma Lundberg, Devin P. Sullivan, Diana Mahdessian, Mathias Uhlén, Peter Thul, Jens S. Andersen, Ulrika Axelsson
Publikováno v:
Danielsson, F, Mahdessian, D, Axelsson, U, Sullivan, D, Uhlén, M, Andersen, J S, Thul, P J & Lundberg, E 2020, ' Spatial Characterization of the Human Centrosome Proteome Opens up New Horizons for a Small but Versatile Organelle ', Proteomics, vol. 20, no. 23, 1900361 . https://doi.org/10.1002/pmic.201900361
After a century of research, the human centrosome continues to fascinate. Based on immunofluorescence and confocal microscopy, an extensive inventory of the protein components of the human centrosome, and the centriolar satellites, with the important
Autor:
Linnéa Strandberg, Jan Mulder, Linn Fagerberg, Wen Zhong, Evelina Sjöstedt, Andreas Hober, Bjørn G. Voldborg, Abdellah Tebani, Peter Thul, Björn Forsström, Devin P. Sullivan, Göran Bergström, David Kotol, Fredrik Pontén, Sara Kanje, Anders Gummesson, Borbala Katona, Sophia Hober, Åsa Sivertsson, Jochen M. Schwenk, Anna Berling, Emil Lindström, Jimmy Vuu, Anne-Sophie Svensson, Jens Nielsen, Burcu Ayoglu, Emma Lundberg, Magdalena Malm, Cecilia Lindskog, Per Oksvold, Tea Dodig-Crnković, Charlotte Stadler, Ragna S. Häussler, Julia Scheffel, Melanie Dannemeyer, Hanna Tegel, Anna-Luisa Volk, Max J. Karlsson, Adil Mardinoglu, Martin Zwahlen, Magnus Lundqvist, Siri Ekblad, Peter Nilsson, Mathias Uhlén, Kalle von Feilitzen, Frida Danielsson, Anna Månberg, Jonathan L. Robinson, Diana Mahdessian, Elisa Pin, Fredrik Edfors, Johan Rockberg, Mun-Gwan Hong
Publikováno v:
Science signaling. 12(609)
The proteins secreted by human cells (collectively referred to as the secretome) are important not only for the basic understanding of human biology but also for the identification of potential targets for future diagnostics and therapies. Here, we p
Autor:
Radek Fedr, Mikael Altun, Johan Boström, Diana Mahdessian, Jiřina Medalová, Vítězslav Bryja, Emma Lundberg, Sten Linnarsson, Alena Salašová, Petra Sekyrova, Zuzana Sramkova, Carolyn Marks, Helena A.D. Johard, Karel Souček, Michael Andäng
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0188772 (2017)
PLoS ONE, Vol 12, Iss 12, p e0188772 (2017)
The cell cycle coordinates core functions such as replication and cell division. However, cell-cycle-regulated transcription in the control of non-core functions, such as cell identity maintenance through specific transcription factors (TFs) and sign
Autor:
Emma Lundberg, Hammou Ait Blal, Marie Skogs, Mathias Uhlén, Charlotte Stadler, Diana Mahdessian, Frida Danielsson, Martin Hjelmare, Mikaela Wiking
Publikováno v:
Journal of Proteome Research. 12:299-307
One of the major challenges of a chromosome-centric proteome project is to explore in a systematic manner the potential proteins identified from the chromosomal genome sequence, but not yet characterized on a protein level. Here, we describe the use