Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Diana M. Barnes"'
Autor:
Patricia Gorman, Diana M. Barnes, William D. Foulkes, Kwok Y. Lee, Maryou B K Lambros, Helga B. Salvesen, Elinor J. Sawyer, Ian Tomlinson, Ian C. Talbot, Rebecca Roylance, Lars A. Akslen, Trivadi S. Ganesan, Walter F. Bodmer, Cheryl Gillett, Ian Jacobs, Sarah Halford, Nicola MacDonald, Andrew M. Hanby
This study assessed whether low-level microsatellite instability (MSI-L) is a phenomenon specific to colorectal cancers or is also present in other tumour types. Breast (grade III ductal and lobular), endometrial and ovarian carcinomas, as well as co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a561bb02f0fab7b53e557d4cafc5d7
https://ora.ox.ac.uk/objects/uuid:68c02ed0-73e3-46bd-832f-2fc46b8b2ee1
https://ora.ox.ac.uk/objects/uuid:68c02ed0-73e3-46bd-832f-2fc46b8b2ee1
Autor:
Audrey Ardern-Jones, Doug Easton, Richard Camplejohn, Rosalind A. Eeles, R Gilchrist, Diana Eccles, Diana M. Barnes, E McKenzie-Edwards, Shirley Hodgson, P M Duddy
Publikováno v:
British Journal of Cancer
We have previously shown that peripheral blood lymphocytes (PBL) from individuals carrying a germline TP53 mutation show a dramatically reduced apoptotic response to radiation. As part of a study of this phenomenon, we also investigated apoptotic res
Publikováno v:
British Journal of Cancer
ST7 is a candidate tumour suppressor gene at human chromosome locus 7q31.1. We have performed mutational analysis of ST7 in a wide-range of cell lines and primary epithelial cancers and detected only one missense change in a breast cancer cell line.
Autor:
Graham R. Taylor, Ruth Charlton, Diana M. Barnes, Richard Camplejohn, Xin Lu, C E Chu, P M Duddy, J Rutherford, P Chumas
Publikováno v:
British Journal of Cancer
This report describes an individual with a rare choroid plexus papilloma in adulthood (age 29) after earlier having an osteosarcoma (age 22). The results from this study, and others, suggest that it may be advisable to consider the possibility of a g
Autor:
Cheryl Gillett, J Lynch, Richard Camplejohn, R Pattekar, Diana M. Barnes, K Ryder, Andrew M. Hanby
Publikováno v:
The Journal of Pathology. 196:275-279
The ability to predict how long a patient diagnosed with breast cancer is likely to survive is still imprecise, despite numerous studies which have identified potential prognostic markers. The ‘established’ markers such as nodal status, tumour si
Autor:
K Ryder, Paul A. Townsend, Diana M. Barnes, Ruey Ho Kao, Richard Poulsom, Andrew M. Hanby, Edwin A. Dublin, Ian R. Hart, Graham Packham, Ramsey I. Cutress
Publikováno v:
The Journal of Pathology. 197:51-59
BAG-1 (BCL-2 athanogene-1), a multifunctional protein which associates with steroid hormone receptors (including the oestrogen receptor) and the anti-apoptotic BCL-2 protein, regulates steroid hormone-dependent transcription and apoptosis. Direct int
Autor:
Diana M. Barnes, A.M. Hanby
Publikováno v:
Histopathology. 38:271-274
Autor:
David Miles, R D Liebman, Diana M. Barnes, D Skilton, R J Springall, K Ryder, Cheryl Gillett, Andrew M. Hanby
Publikováno v:
The Journal of Pathology. 193:433-441
Many studies have investigated the relationship between the E-cadherin/catenin axis and breast cancer biology and yet, unlike the studies in other tumour systems, which have shown a relationship between down-regulation and poor survival, no clear ass
Publikováno v:
The American Journal of Pathology. 157:1219-1227
The urokinase-type plasminogen activator (uPA) system has been implicated in tumor spread. We have used immunohistochemistry to examine three components of this system, ie, uPA, uPA receptor (uPAR), and plasminogen activator inhibitor-1 (PAI-1), in a
Autor:
Rosalind A. Eeles, R Gilchrist, Richard Camplejohn, Diana M. Barnes, P M Duddy, C Miner, M E Lomax, Nayanta Sodha, P Alarcon-Gonzalez
Publikováno v:
British Journal of Cancer
We have tested two rapid assays of p53 function, namely the apoptotic assay and the FASAY as means of detecting germline p53 mutations in members of Li–Fraumeni and Li–Fraumeni-like families. Results of the functional assays have been compared wi