Výsledky vyhledávání - "Diana M. Alejo"

An adenovirus vectored mucosal adjuvant augments protection of mice immunized intranasally with an adenovirus-vectored foot-and-mouth disease virus subunit vaccine

Autor: Marvin J. Grubman, Edan R. Tulman, Diana M. Alejo, Debra Rood, X. Liao, Fayna Diaz-San Segundo, Lawrence K. Silbart, Mauro P. Moraes, Camila C. Dias

Publikováno v: Vaccine. 31:2302-2309

Foot-and-mouth disease virus (FMDV) is a highly contagious pathogen that causes severe morbidity and economic losses to the livestock industry in many countries. The oral and respiratory mucosae are the main ports of entry of FMDV, so the stimulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20be563e1f754d332a33d972b6149120
https://doi.org/10.1016/j.vaccine.2013.02.060

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Xenoepitope substitution avoids deceptive imprinting and broadens the immune response to foot-and-mouth disease virus

Autor: Roger W. Barrette, Lawrence K. Silbart, Debra Rood, Diana M. Alejo, Steven M. Szczepanek

Publikováno v: Clinical and vaccine immunology : CVI. 19(4)

Many RNA viruses encode error-prone polymerases which introduce mutations into B and T cell epitopes, providing a mechanism for immunological escape. When regions of hypervariability are found within immunodominant epitopes with no known function, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea1b6abe3c33d6cc87cad948dd8276db
https://pubmed.ncbi.nlm.nih.gov/22323558

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