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pro vyhledávání: '"Diana M Sama"'
Autor:
Diana M Sama, Hafiz Mohmmad Abdul, Jennifer L Furman, Irina A Artiushin, David E Szymkowski, Stephen W Scheff, Christopher M Norris
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38170 (2012)
The role of tumor necrosis factor α (TNF) in neural function has been investigated extensively in several neurodegenerative conditions, but rarely in brain aging, where cognitive and physiologic changes are milder and more variable. Here, we show th
Externí odkaz:
https://doaj.org/article/9070eedaf2674801b42def61428bc4c7
Autor:
Kathryn E. Saatman, Friedrich Metzger, Stefanie Saenger, Diana M. Sama, Shaun W. Carlson, Binoy Joseph
Publikováno v:
Restor Neurol Neurosci
Background Traumatic brain injury can result in lasting cognitive dysfunction due to degeneration of mature hippocampal neurons as well as the loss of immature neurons within the dentate gyrus. While endogenous neurogenesis affords a partial recovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b220a4edf05e32986ae3f2bb10ba78
https://doi.org/10.3233/rnn-180831
https://doi.org/10.3233/rnn-180831
Autor:
Diana M. Sama, Kathryn E. Saatman, Sindhu K. Madathil, Shaun W. Carlson, Jinhui Chen, Xiang Gao
Publikováno v:
Journal of neuropathology and experimental neurology. 73(8)
Traumatic brain injury (TBI) is associated with neuronal damage or neuronal death in the hippocampus, a region critical for cognitive function. Immature neurons within the hippocampal neurogenic niche are particularly susceptible to TBI. Therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::277dba770fab3df37a40d502b62d8b68
https://pubmed.ncbi.nlm.nih.gov/25003234
https://pubmed.ncbi.nlm.nih.gov/25003234
Autor:
Diana M. Sama, Christopher M. Norris
Publikováno v:
Ageing research reviews. 12(4)
Some of the best biomarkers of age-related cognitive decline are closely linked to synaptic function and plasticity. This review highlights several age-related synaptic alterations as they relate to Ca(2+) dyshomeostasis, through elevation of intrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f768ac58e103fbc45b7a5c1029b74399
https://pubmed.ncbi.nlm.nih.gov/23751484
https://pubmed.ncbi.nlm.nih.gov/23751484
Autor:
M. Paul Murphy, Linda J. Van Eldik, Diana M. Sama, Tina L. Beckett, Adam D. Bachstetter, John C. Gant, Jennifer L. Furman, Christopher M. Norris
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(46)
Astrocytes are the most abundant cell type in the brain and play a critical role in maintaining healthy nervous tissue. In Alzheimer's disease (AD) and most other neurodegenerative disorders, many astrocytes convert to a chronically “activated” p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46338ee3e30ba46d3f35b653abd76711
https://pubmed.ncbi.nlm.nih.gov/23152597
https://pubmed.ncbi.nlm.nih.gov/23152597