Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Diana M Merino"'
Autor:
Chen Zhao, Li Chen, Albrecht Stenzinger, Yali Li, Naiyer Rizvi, Jeff Allen, Matthew Hellmann, Diana M Merino, Lisa M McShane, David Fabrizio, Vincent Funari, Shu-Jen Chen, James R White, Paul Wenz, Jonathan Baden, J Carl Barrett, Ruchi Chaudhary, Wangjuh (Sting) Chen, Jen-Hao Cheng, Dinesh Cyanam, Jennifer S Dickey, Vikas Gupta, Elena Helman, Joerg Maas, Arnaud Papin, Rajesh Patidar, Katie J Quinn, Hongseok Tae, Christine Ward, Mingchao Xie, Ahmet Zehir, Manfred Dietel, Mark Stewart
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Tumor mutational burden (TMB), defined as the number of somatic mutations per megabase of interrogated genomic sequence, demonstrates predictive biomarker potential for the identification of patients with cancer most likely to respond to i
Externí odkaz:
https://doaj.org/article/e8663839837544db9634250292b948f0
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Appendix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eaefeb9be99647fd51217c8ee4e4797
https://doi.org/10.1158/1078-0432.22454475
https://doi.org/10.1158/1078-0432.22454475
Autor:
David Malkin, Richard J. Gilbertson, David W. Ellison, Uri Tabori, Michael D. Taylor, Cynthia Hawkins, Eric Bouffet, Rosanna Weksberg, Jonathan L. Finlay, Nada Jabado, Maria Isabel Achatz, Stefan M. Pfister, Rishi Lulla, Eugene I. Hwang, Brent T. Harris, Myran Ben-Arush, Rina Dvir, Sanaa Choufani, Ana Novokmet, Ruth Tatevossian, David Shih, Vijay Ramaswamy, Stephen Mack, Malgorzata Pienkowska, Anita Villani, Adam Shlien, Diana M. Merino
Figure S1. Sample flow-chart describing the number of biological samples and clinical data obtained through an international multi-institutional effort and the distribution of samples in each microarray
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361d41fd9453dbfadfe788305a9f4f51
https://doi.org/10.1158/1078-0432.22454472
https://doi.org/10.1158/1078-0432.22454472
Autor:
Robert J. Wechsler-Reya, Richard J. Gilbertson, Martine F. Roussel, Rosalie C. Sears, Charles G. Eberhart, Scott R. VandenBerg, David W. Ellison, David Malkin, Michael D. Taylor, Kim D. Janda, Ryan J. Shirey, Erin N. Kiehna, Shahab Asgharzadeh, Girish Dhall, Kun-Wei Liu, Lianne Q. Chau, Andrew P. Hodges, Xiaohui Guo, Yong-Dong Wang, Brian L. Murphy, Nicholas Light, Diana M. Merino, Jun Wang
Choroid plexus carcinoma (CPC) is a rare brain tumor that occurs most commonly in very young children and has a dismal prognosis despite intensive therapy. Improved outcomes for patients with CPC depend on a deeper understanding of the mechanisms und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33084c165d36492c3edf52d6528ba1ab
https://doi.org/10.1158/0008-5472.c.6511427.v1
https://doi.org/10.1158/0008-5472.c.6511427.v1
Autor:
Robert J. Wechsler-Reya, Richard J. Gilbertson, Martine F. Roussel, Rosalie C. Sears, Charles G. Eberhart, Scott R. VandenBerg, David W. Ellison, David Malkin, Michael D. Taylor, Kim D. Janda, Ryan J. Shirey, Erin N. Kiehna, Shahab Asgharzadeh, Girish Dhall, Kun-Wei Liu, Lianne Q. Chau, Andrew P. Hodges, Xiaohui Guo, Yong-Dong Wang, Brian L. Murphy, Nicholas Light, Diana M. Merino, Jun Wang
Figure S2 shows H&E staining on Atoh1-Cre CPC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930bb0625859086a300f9ac5b70930fe
https://doi.org/10.1158/0008-5472.22423127
https://doi.org/10.1158/0008-5472.22423127
Autor:
Robert J. Wechsler-Reya, Richard J. Gilbertson, Martine F. Roussel, Rosalie C. Sears, Charles G. Eberhart, Scott R. VandenBerg, David W. Ellison, David Malkin, Michael D. Taylor, Kim D. Janda, Ryan J. Shirey, Erin N. Kiehna, Shahab Asgharzadeh, Girish Dhall, Kun-Wei Liu, Lianne Q. Chau, Andrew P. Hodges, Xiaohui Guo, Yong-Dong Wang, Brian L. Murphy, Nicholas Light, Diana M. Merino, Jun Wang
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a32032db67b1ae478c12e8c976caac
https://doi.org/10.1158/0008-5472.22423106
https://doi.org/10.1158/0008-5472.22423106
Autor:
Robert J. Wechsler-Reya, Richard J. Gilbertson, Martine F. Roussel, Rosalie C. Sears, Charles G. Eberhart, Scott R. VandenBerg, David W. Ellison, David Malkin, Michael D. Taylor, Kim D. Janda, Ryan J. Shirey, Erin N. Kiehna, Shahab Asgharzadeh, Girish Dhall, Kun-Wei Liu, Lianne Q. Chau, Andrew P. Hodges, Xiaohui Guo, Yong-Dong Wang, Brian L. Murphy, Nicholas Light, Diana M. Merino, Jun Wang
Figure S1 shows other models of choroid plexus tumors generated from different Cre lines and their corresponding Kaplan-Meier survival curve.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fac174de6306d70d2f7c9b9a53b7744
https://doi.org/10.1158/0008-5472.22423130.v1
https://doi.org/10.1158/0008-5472.22423130.v1
Autor:
Robert J. Wechsler-Reya, Richard J. Gilbertson, Martine F. Roussel, Rosalie C. Sears, Charles G. Eberhart, Scott R. VandenBerg, David W. Ellison, David Malkin, Michael D. Taylor, Kim D. Janda, Ryan J. Shirey, Erin N. Kiehna, Shahab Asgharzadeh, Girish Dhall, Kun-Wei Liu, Lianne Q. Chau, Andrew P. Hodges, Xiaohui Guo, Yong-Dong Wang, Brian L. Murphy, Nicholas Light, Diana M. Merino, Jun Wang
Figure S4 shows the expression of MYC and Ki67 by immunohistochemistry in human choroid plexus carcinoma patient specimens.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c0f27c8306d2dfa47adec6bc043b39
https://doi.org/10.1158/0008-5472.22423121
https://doi.org/10.1158/0008-5472.22423121
Autor:
Robert J. Wechsler-Reya, Richard J. Gilbertson, Martine F. Roussel, Rosalie C. Sears, Charles G. Eberhart, Scott R. VandenBerg, David W. Ellison, David Malkin, Michael D. Taylor, Kim D. Janda, Ryan J. Shirey, Erin N. Kiehna, Shahab Asgharzadeh, Girish Dhall, Kun-Wei Liu, Lianne Q. Chau, Andrew P. Hodges, Xiaohui Guo, Yong-Dong Wang, Brian L. Murphy, Nicholas Light, Diana M. Merino, Jun Wang
Figure S7 shows effects of CDK4/6 inhibitors on viability of mouse CPC cells and drug synergy between Triptolide and Dinaciclib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698865732992d4dab362dd10fcaccaa0
https://doi.org/10.1158/0008-5472.22423109.v1
https://doi.org/10.1158/0008-5472.22423109.v1
Autor:
Robert J. Wechsler-Reya, Richard J. Gilbertson, Martine F. Roussel, Rosalie C. Sears, Charles G. Eberhart, Scott R. VandenBerg, David W. Ellison, David Malkin, Michael D. Taylor, Kim D. Janda, Ryan J. Shirey, Erin N. Kiehna, Shahab Asgharzadeh, Girish Dhall, Kun-Wei Liu, Lianne Q. Chau, Andrew P. Hodges, Xiaohui Guo, Yong-Dong Wang, Brian L. Murphy, Nicholas Light, Diana M. Merino, Jun Wang
Figure S3 shows lineage tracing of Blbp+ progenitors in the choroid plexus of the lateral ventricle and 4th ventricle of the mouse brain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36235603b0420c5d2d542b053ee6bf95
https://doi.org/10.1158/0008-5472.22423124
https://doi.org/10.1158/0008-5472.22423124