Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Diana Lieber"'
Autor:
Diana Lieber, Daniel Hochdorfer, Dagmar Stoehr, Axel Schubert, Ramin Lotfi, Tobias May, Dagmar Wirth, Christian Sinzger
Publikováno v:
BioTechniques, Vol 59, Iss 3, Pp 127-136 (2015)
Infection of vascular endothelial cells (ECs) is assumed to contribute to dissemination of human cytomegalovirus (HCMV). Investigation of virus–host interactions in ECs such as human umbilical vein endothelial cells (HUVECs) is limited due to the l
Externí odkaz:
https://doaj.org/article/d9a52ffcb26742e5b539bf5dcaf0ca78
Autor:
Cora Stegmann, Daniel Hochdorfer, Diana Lieber, Narmadha Subramanian, Dagmar Stöhr, Kerstin Laib Sampaio, Christian Sinzger
Publikováno v:
PLoS Pathogens, Vol 13, Iss 4, p e1006273 (2017)
Human cytomegalovirus (HCMV) is a widely distributed herpesvirus that causes significant morbidity in immunocompromised hosts. Inhibitors of viral DNA replication are available, but adverse effects limit their use. Alternative antiviral strategies ma
Externí odkaz:
https://doaj.org/article/b9db6d7daa8f438dba80b1f4479b0bd8
Autor:
Anna Katharina Maier, Raimund Jung, Clarissa Villinger, Axel Schubert, Paul Walther, Christian Sinzger, Diana Lieber
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169580 (2017)
Widely used methods for quantification of human cytomegalovirus (HCMV) infection in cell culture such as immunoblotting or plaque reduction assays are generally restricted to low throughput and require time-consuming evaluation. Up to now, only few H
Externí odkaz:
https://doaj.org/article/c831f8802df14645a494c997d25aa2cb
Autor:
Laura A. Fast, Snježana Mikuličić, Anna Fritzen, Jonas Schwickert, Fatima Boukhallouk, Daniel Hochdorfer, Christian Sinzger, Henar Suarez, Peter N. Monk, María Yáñez-Mó, Diana Lieber, Luise Florin
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3007 (2018)
Tetraspanins are suggested to regulate the composition of cell membrane components and control intracellular transport, which leaves them vulnerable to utilization by pathogens such as human papillomaviruses (HPV) and cytomegaloviruses (HCMV) to faci
Externí odkaz:
https://doaj.org/article/db0f353513c44e2e84785ac8e3a88d53
Autor:
Yolaine Cavignac, Diana Lieber, Kerstin Laib Sampaio, Johannes Madlung, Tobias Lamkemeyer, Gerhard Jahn, Alfred Nordheim, Christian Sinzger
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131614 (2015)
While it is well established that human cytomegalovirus (HCMV) upregulates many cellular proteins and incorporates several of them into its virion, little is known about the functional relevance of such virus-host interactions. Two cellular proteins,
Externí odkaz:
https://doaj.org/article/4e4287a5a0b84174a4b2b20959f14b11
Publikováno v:
Biochemical Society Transactions. 45:489-497
Members of the tetraspanin family have been identified as essential cellular membrane proteins in infectious diseases by nearly all types of pathogens. The present review highlights recently published data on the role of tetraspanin CD151, CD81, and
Autor:
Christian Sinzger, Jessica Julia Falk, Diana Lieber, Barbara Kropff, Kerstin Laib Sampaio, Michael Mach, Cora Stegmann
Publikováno v:
Journal of Virological Methods. 235:182-189
For many questions in human cytomegalovirus (HCMV) research, assays are desired that allow robust and fast quantification of infection efficiencies under high-throughput conditions. The secreted Gaussia luciferase has been demonstrated as a suitable
Autor:
Christina Funk, Michael Biggel, Jacqueline Leimser, Verena Raschbichler, Caroline C. Friedel, Eileen K. Arnold, Jens Wetschky, Zsolt Ruzsics, Diana Lieber, Susanne M. Bailer
Publikováno v:
Traffic (Copenhagen, Denmark)
Morphogenesis of herpesviral virions is initiated in the nucleus but completed in the cytoplasm. Mature virions contain more than 25 tegument proteins many of which perform both nuclear and cytoplasmic functions suggesting they shuttle between these
Autor:
Axel Schubert, Diana Lieber, Daniel Hochdorfer, Ramin Lotfi, Christian Sinzger, Tobias May, Dagmar Wirth, Dagmar Stoehr
Publikováno v:
BioTechniques. 59:127-136
Infection of vascular endothelial cells (ECs) is assumed to contribute to dissemination of human cytomegalovirus (HCMV). Investigation of virus–host interactions in ECs such as human umbilical vein endothelial cells (HUVECs) is limited due to the l
Autor:
Ralf Zimmer, Mihaela Zavolan, Diana Lieber, Lars Dölken, Jürgen Haas, Lukasz Jaskiewicz, Florian Erhard, Georg Malterer
Publikováno v:
Erhard, F, Haas, J, Lieber, D, Malterer, G, Jaskiewicz, L, Zavolan, M, Doelken, L & Zimmer, R 2014, ' Widespread context dependency of microRNA-mediated regulation ', Genome Research, vol. 24, no. 6, pp. 906-919 . https://doi.org/10.1101/gr.166702.113
Gene expression is regulated in a context-dependent, cell-type-specific manner. Condition-specific transcription is dependent on the presence of transcription factors (TFs) that can activate or inhibit its target genes (global context). Additional fa