Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Diana Lenzner"'
Autor:
Drew R. Michanowicz, Conrad D. Volz, Talal El-Hefnawy, Lara M. Renz, Charles Christian, Diana Lenzner, Kyle Ferrar
Publikováno v:
Ecotoxicology. 22:632-641
Pollution from xenoestrogens has been discovered in the aquatic environment of the Greater Pittsburgh Area and is suspected to be caused by the failing sewer system. Personal care products and plasticizers have the potential to enter the water supply
Autor:
Xiaoping Liu, Clayton A. Smith, Qiong Yang, Qingde Wang, Lisa J. Robinson, Diana Lenzner, Jingzhou Hou, Maura Gasparetto, Richard A. Steinman
Publikováno v:
International Journal of Cancer. 132:1741-1750
Patients with chronic myelogenous leukemia (CML) respond well to tyrosine kinase inhibitors (TKIs) of the Bcr-Abl oncoprotein. However, intolerance and resistance to these agents remains a challenge, and TKI’s are unable to eradicate rare leukemia-
Autor:
John M. Jakicic, Meredith Hennon, Ashley S. Felix, James P. DeLany, Faina Linkov, Anna Lokshin, Bret H. Goodpaster, Dana H. Bovbjerg, Yan Lin, G. Larry Maxwell, Diana Lenzner
Publikováno v:
Gynecologic Oncology. 125:114-119
Obesity is a major risk factor for the development of endometrial cancer (EC). An improved understanding of biologic mechanisms associated with weight loss, including alteration in inflammation, hormonal balance, and cancer antigens expression may le
Autor:
Haroon A. Choudry, Lekshmi Ramalingam, Matthew P. Holtzman, David L. Bartlett, James F. Pingpank, Jennifer L. Steel, Herbert J. Zeh, Diana Lenzner, Steven A. Ahrendt, Frances Austin, Magesh Sathaiah, Arun Mavanur
Publikováno v:
Annals of Surgical Oncology. 19:1386-1393
Peritoneal carcinomatosis (PC) in the setting of mucinous appendiceal neoplasms is characterized by the intraperitoneal accumulation of mucinous ascites and mucin-secreting epithelial cells that leads to progressive compression of intra-abdominal org
Autor:
Jill M. Siegfried, Laura P. Stabile, Phouthone Keohavong, K. Jin Kim, Stephanie R. Land, Mary E. Rothstein, Naftali Kaminski, Autumn Gaither-Davis, Diana Lenzner
Publikováno v:
Cancers
Cancers, Vol 2, Iss 4, Pp 2153-2170 (2010)
Cancers; Volume 2; Issue 4; Pages: 2153-2170
Cancers, Vol 2, Iss 4, Pp 2153-2170 (2010)
Cancers; Volume 2; Issue 4; Pages: 2153-2170
EGFR and c-Met are both overexpressed in lung cancer and initiate similar downstream signaling, which may be redundant. To determine how frequently ligands that initiate signaling of both pathways are found in lung cancer, we analyzed serum for hepat
Autor:
Joseph L. Kelley, Diana Lenzner, Anda M. Vlad, Julia Thaller, Kelly Colonello, Yun Wang, Raluca Budiu, Fredric V. Price, Robert P. Edwards, Peggy A. Crowley-Nowick
Publikováno v:
Cancer Immunology, Immunotherapy. 59:293-301
Ovarian cancer patients with persistent (platinum-resistant) or progressive (platinum-refractory) disease respond poorly to second line chemotherapy and have low survival expectancy. New and improved therapeutic approaches are needed and immune biolo
Autor:
Philippe Guillaume, Hongmei Shen, Soldano Ferrone, Cindy Sander, Hassane M. Zarour, Zhaojun Sun, Pavol Kudela, Immanuel F. Luescher, Diana Lenzner, Julien Fourcade, Stephanie R. Land, John M. Kirkwood
Publikováno v:
Journal of immunology, vol. 182, no. 9, pp. 5240-5249
The programmed death 1 (PD-1) receptor is a negative regulator of activated T cells and is up-regulated on exhausted virus-specific CD8+ T cells in chronically infected mice and humans. Programmed death ligand 1 (PD-L1) is expressed by multiple tumor
Autor:
Adam M. Farkas, GuangFeng Zhang, Harish Srinivas, Diana Lenzner, Stephanie R. Land, Kira L. Lathrop, Anil V. Parwani, Xuwan Liu
Publikováno v:
Molecular Endocrinology. 23:146-156
Recent studies have shown that estrogens promote the growth of lung cancer cells and may potentially be responsible for increased susceptibility to lung cancer in women. These observations raise the possibility of using antiestrogens in treating and
Autor:
Joanna M. Brell, Ramesh K. Ramanathan, James J. Schlesselman, Terry Evans, Linda Rath, S. Dranko, Amy Schmotzer, Khalid Matin, Robert Volkin, Gauri J. Kiefer, Diana Lenzner
Publikováno v:
Oncology. 76:270-274
Background: There is no standard second-line therapy for advanced pancreatic cancer (APC). We evaluated the epidermal growth factor receptor (EGFR) inhibitor gefitinib and docetaxel in a phase II study following gemcitabine failure. Methods: EGFR ove
Autor:
Miroslaw J. Szczepanski, Albert B. DeLeo, Diana Lenzner, Marta Szajnik, Theresa L. Whiteside, Marta Glura, Maciej Zabel, Esther Elishaev, Carmen Visus
17β-hydroxysteroid dehydrogenase isoform 12 (HSD17B12) overexpression is associated with poor clinical outcome in invasive ductal carcinoma of the breast. Here, we evaluated HSD17B12 overexpression and its activity in ovarian carcinoma (OvCa) to det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38811123b71f2371fd84339e7c1d60ee
https://europepmc.org/articles/PMC3607433/
https://europepmc.org/articles/PMC3607433/