Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Diana L. Shuster"'
Autor:
David E. Bernstein, Albert Tran, Paul Martin, Kris V. Kowdley, Marc Bourliere, Mark S. Sulkowski, Paul J. Pockros, Boris Renjifo, Deli Wang, Diana L. Shuster, Daniel E. Cohen, Ira M. Jacobson
Publikováno v:
Kidney International Reports, Vol 4, Iss 2, Pp 245-256 (2019)
Introduction: Patients with hepatitis C virus (HCV) infection and chronic kidney disease (CKD) are a high-priority population for treatment. Methods: We performed a post hoc pooled efficacy and safety analysis that included HCV genotype 1–infected
Externí odkaz:
https://doaj.org/article/fee2a1ab44074b91b2b9751f3f900276
Autor:
Daniel H. Leung, Stefan Wirth, Betty B. Yao, Rolando M. Viani, Regino P. Gonzalez‐Peralta, Maureen M. Jonas, Steven J. Lobritto, Michael R. Narkewicz, Etienne Sokal, Clàudia Fortuny, Evelyn K. Hsu, Antonio Del Valle‐Segarra, Jiuhong Zha, Lois Larsen, Li Liu, Diana L. Shuster, Daniel E. Cohen, Philip Rosenthal
Publikováno v:
Hepatology Communications, Vol 2, Iss 11, Pp 1311-1319 (2018)
In adults, treatment of hepatitis C virus (HCV) infection with ombitasvir (OBV)/paritaprevir (PTV)/ritonavir (r) with or without dasabuvir (DSV) and ±ribavirin (RBV) results in high rates of sustained virologic response (SVR). However, these regimen
Externí odkaz:
https://doaj.org/article/7c2878afc38e4773af4d2a41dab214ac
Autor:
David M. Haas, Mary F. Hebert, Tracy A. Manuck, Shannon K. Flood Nichols, Xiaosu Ma, Zane A. Brown, Steve N. Caritis, Laura M. Shireman, Mahmoud Ahmed, Raman Venkataramanan, Laura S. Haneline, Linda Morris Brown, Thomas R. Easterling, Alan T.N. Tita, Diana L. Shuster, Shannon Clark, Danny D. Shen, Sara K. Quinney, Kenneth E. Thummel, Zhaoxia Ren
Publikováno v:
J Clin Pharmacol
Gestational diabetes mellitus is a condition similar to type 2 diabetes mellitus (T2DM) in that patients are unable to compensate for the degree of insulin resistance, and both conditions are often treated with metformin. The comparative pharmacodyna
Publikováno v:
Current reviews in clinical and experimental pharmacology. 17(1)
Cannabis has become legal in much of the United States similar to many other countries, for either recreational or medical use. The use of cannabis products is rapidly increasing while the body of knowledge of its myriad of effects still lags. In vit
Autor:
Diana L. Shuster, Gina Pastino
Publikováno v:
Current reviews in clinical and experimental pharmacology. 17(1)
The use and acceptance of cannabis, either medically or recreationally, has substantially outpaced the collection of data necessary to evaluate it’s use in any population. However, the mere widespread availability does not imply the absence of risk
Autor:
Boris Renjifo, Marc Bourlière, Deli Wang, Albert Tran, David E. Bernstein, Daniel E. Cohen, Ira M. Jacobson, Paul J. Martin, Kris V. Kowdley, Diana L. Shuster, Paul J. Pockros, Mark S. Sulkowski
Publikováno v:
Kidney International Reports
Kidney International Reports, Vol 4, Iss 2, Pp 245-256 (2019)
Kidney International Reports, Vol 4, Iss 2, Pp 245-256 (2019)
Introduction: Patients with hepatitis C virus (HCV) infection and chronic kidney disease (CKD) are a high-priority population for treatment. Methods: We performed a post hoc pooled efficacy and safety analysis that included HCV genotype 1–infected
Publikováno v:
Clinical Pharmacokinetics. 56:1103-1113
Ombitasvir is a potent, nonstructural protein 5A inhibitor of the hepatitis C virus (HCV) that is used in combination with other direct-acting antivirals for the treatment of chronic HCV infection. Ombitasvir is predominantly metabolized by amide hyd
Autor:
Rajeev M. Menon, Eric Cohen, Bifeng Ding, Diana L. Shuster, Hong Li, Daniel E. Cohen, Melissa Jewett, Jiuhong Zha, Amit Khatri
Publikováno v:
European journal of clinical pharmacology. 75(2)
To characterize the pharmacokinetics of ombitasvir, paritaprevir, ritonavir, dasabuvir, and ribavirin in hepatitis C virus (HCV)-infected patients with chronic kidney disease stage 4 (CKD4) or end-stage renal disease (ESRD), including those on dialys
Autor:
Stefan Wirth, Regino P. Gonzalez-Peralta, Evelyn K. Hsu, Diana L. Shuster, A. Del Valle-Segarra, Daniel H. Leung, Betty B. Yao, Lois Larsen, Claudia Fortuny, Maureen M. Jonas, Michael R. Narkewicz, Philip J. Rosenthal, Jiuhong Zha, Steven J. Lobritto, Etienne Sokal, Daniel E. Cohen, Rolando M Viani, Li Liu
Publikováno v:
Journal of Hepatology. 66:S300-S301
Autor:
Diana L. Shuster, Mark F. Rosenberg, Zhanglin Ni, Chunsheng Zhao, Qingcheng Mao, Zsolt Bikádi
Publikováno v:
Biochemistry. 50:8057-8066
The human breast cancer resistance protein (BCRP/ABCG2) confers multidrug resistance and mediates the active efflux of drugs and xenobiotics. BCRP contains one nucleotide-binding domain (NBD) followed by one membrane-spanning domain (MSD). We investi