Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Diana L. Price"'
Autor:
Diana L. Price, Asma Khan, Rachel Angers, Alvaro Cardenas, Maria Key Prato, Massimo Bani, Douglas W. Bonhaus, Martin Citron, Anja-Leona Biere
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Direct targeting of alpha-synuclein (ASYN) has emerged as a disease-modifying strategy for Parkinson’s disease and other synucleinopathies which is being approached using both small molecule compounds and ASYN-targeted biologics. Minzasolm
Externí odkaz:
https://doaj.org/article/528ea93e40cf43c7b16378bd59b03e20
Autor:
Diana L. Price, Asma Khan, Rachel Angers, Alvaro Cardenas, Maria Key Prato, Massimo Bani, Douglas W. Bonhaus, Martin Citron, Anja-Leona Biere
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/466b8c60bfbc4bd0ac054e9aff4db5e9
Autor:
Agata Habas, Srinivasa Reddy Natala, Jon K. Bowden-Verhoek, Emily M. Stocking, Diana L. Price, Wolfgang Wrasidlo, Douglas W. Bonhaus, Martin B. Gill
Publikováno v:
International Journal of Inflammation, Vol 2022 (2022)
Toll-like receptors (TLRs) play a critical role in innate immune system responses to damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs). A growing body of evidence suggests that excessive TLR-mediated inna
Externí odkaz:
https://doaj.org/article/cda6d073afc640b9b2f9195a4f22173e
Autor:
Diana L. Price, Maya A. Koike, Asma Khan, Wolfgang Wrasidlo, Edward Rockenstein, Eliezer Masliah, Douglas Bonhaus
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Accumulation of alpha-synuclein (ASYN) in neurons and other CNS cell types may contribute to the underlying pathology of synucleinopathies including Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and Multiple Systems Atrophy (MS
Externí odkaz:
https://doaj.org/article/e92a50d06223471a8b71cbee5518de64
Autor:
Agata Habas, Srinivasa Reddy Natala, Jon K. Bowden-Verhoek, Emily M. Stocking, Diana L. Price, Wolfgang Wrasidlo, Douglas W. Bonhaus, Martin B. Gill
Publikováno v:
International journal of inflammation. 2022
Toll-like receptors (TLRs) play a critical role in innate immune system responses to damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns (PAMPs). A growing body of evidence suggests that excessive TLR-mediated inna
Autor:
Eliezer Masliah, Douglas W. Bonhaus, Diana L. Price, Julian L Wong, Emily M. Stocking, Asma Khan, Carrie Wittmer, Martin B. Gill, Jon K Bowden-Verhoek, Wolfgang Wrasidlo, Robert Johnson, Srinivasa Reddy Natala, Amy Paulino, Michelle Maile, Keith Tatsukawa
Publikováno v:
Brain : a journal of neurology. 144(12)
NPT520-34 is a clinical stage, small molecule being developed for the treatment of Parkinson’s disease and other neurodegenerative disorders. The therapeutic potential of NPT520-34 was first suggested by findings from cell-based assays of alpha-syn
Autor:
Diana L Price, Edward Rockenstein, Kiren Ubhi, Van Phung, Natalie MacLean-Lewis, David Askay, Anna Cartier, Brian Spencer, Christina Patrick, Paula Desplats, Mark H Ellisman, Eliezer Masliah
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14020 (2010)
Dementia with Lewy bodies (DLB) and Parkinson's Disease (PD) are neurodegenerative disorders of the aging population characterized by the abnormal accumulation of alpha-synuclein (alpha-syn). Previous studies have suggested that excitotoxicity may co
Externí odkaz:
https://doaj.org/article/135da3ab6152436fb43eae3c75620b89
Autor:
Wolfgang Wrasidlo, Edward Rockenstein, Eliezer Masliah, Maya A. Koike, Diana L. Price, Asma Khan, Douglas W. Bonhaus
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Accumulation of alpha-synuclein (ASYN) in neurons and other CNS cell types may contribute to the underlying pathology of synucleinopathies including Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and Multiple Systems Atrophy (MSA). In su
Autor:
Eliezer Masliah, Cassia R. Overk, Igor F. Tsigelny, Edward Rockenstein, Christina Patrick, Leslie Crews, Wolf Wrasidlo, Amy Paulino, Tania Gonzales, Diana L. Price, Valentina L. Kouznetsova, Emily Stocking
Publikováno v:
British Journal of Pharmacology. 171:5757-5773
Background and Purpose Anti-retrovirals have improved and extended the life expectancy of patients with HIV. However, as this population ages, the prevalence of cognitive changes is increasing. Aberrant activation of kinases, such as receptor tyrosin
Autor:
Eliezer Masliah, Amy Paulino, Karin Ledolter, Paula Desplats, Wolfgang Wrasidlo, Igor F. Tsigelny, Dieter Meier, Åge A. Skjevik, Margarita Trejo-Morales, Brian Spencer, Robert Konrat, Chunni Zhu, Garima Dutta, Simona Eleuteri, Marie-Françoise Chesselet, Tania Gonzalez-Ruelas, Cassia R. Overk, Edward Rockenstein, Thomas C. Schwarz, Diana L. Price, Douglas W. Bonhaus, Valentina L. Kouznetsova, Herbert Moessler, Stefan Winter
Publikováno v:
Brain : a journal of neurology, vol 139, iss Pt 12
Abnormal accumulation and propagation of the neuronal protein α-synuclein has been hypothesized to underlie the pathogenesis of Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. Here we report a de novo-developed compound (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e17d784387b62c9ca849ff394fe12f
https://escholarship.org/uc/item/3dk4t6f7
https://escholarship.org/uc/item/3dk4t6f7