Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Diana L. Christian"'
Autor:
Amanda M. Smith, Taylor A. LaValle, Marwan Shinawi, Sai M. Ramakrishnan, Haley J. Abel, Cheryl A. Hill, Nicole M. Kirkland, Michael P. Rettig, Nichole M. Helton, Sharon E. Heath, Francesca Ferraro, David Y. Chen, Sangeeta Adak, Clay F. Semenkovich, Diana L. Christian, Jenna R. Martin, Harrison W. Gabel, Christopher A. Miller, Timothy J. Ley
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Germline mutations in the DNMT3A gene can cause an overgrowth syndrome associated with behavioural and hematopoietic phenotypes. Here the authors describe a mouse model of this syndrome that recapitulates many of these features, including conserved a
Externí odkaz:
https://doaj.org/article/5e0d8e3763324ed0920eb1d6b6fbeadf
Autor:
Robert Dantzer, John H. Lee, Paola D. Vermeer, Phillip S. Gross, Daniel W. Vermeer, Jessica M. Molkentine, Diana L. Christian, Elisabeth G. Vichaya, Aaron J. Grossberg
This file shows burrowing behavior in tumor-bearing mice that were or were not treated with systemic IL-1ra.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0390c01db56bf4da9c9dc0a79b5ddf
https://doi.org/10.1158/0008-5472.22417433
https://doi.org/10.1158/0008-5472.22417433
Autor:
Robert Dantzer, John H. Lee, Paola D. Vermeer, Phillip S. Gross, Daniel W. Vermeer, Jessica M. Molkentine, Diana L. Christian, Elisabeth G. Vichaya, Aaron J. Grossberg
Fatigue is the most common symptom of cancer at diagnosis, yet causes and effective treatments remain elusive. As tumors can be highly inflammatory, it is generally accepted that inflammation mediates cancer-related fatigue. However, evidence to supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157c65357c261407837451eb79830d0d
https://doi.org/10.1158/0008-5472.c.6509846.v1
https://doi.org/10.1158/0008-5472.c.6509846.v1
Autor:
Robert Dantzer, John H. Lee, Paola D. Vermeer, Phillip S. Gross, Daniel W. Vermeer, Jessica M. Molkentine, Diana L. Christian, Elisabeth G. Vichaya, Aaron J. Grossberg
This file contains methods and references for data presented in the supplement and legends for Supplementary Figures S1-S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f556f5b44eed1b383dccfc72bdc836b
https://doi.org/10.1158/0008-5472.22417430.v1
https://doi.org/10.1158/0008-5472.22417430.v1
Autor:
Nicole M. Kirkland, Sharon Heath, Francesca Ferraro, Haley J. Abel, Christopher A. Miller, Jenna R. Martin, David Y. Chen, Harrison W. Gabel, Clay F. Semenkovich, Sai Mukund Ramakrishnan, Taylor A. LaValle, Cheryl A. Hill, Michael P. Rettig, Sangeeta Adak, Amanda Smith, Marwan Shinawi, Nichole M. Helton, Timothy J. Ley, Diana L. Christian
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications
Germline pathogenic variants in DNMT3A were recently described in patients with overgrowth, obesity, behavioral, and learning difficulties (DNMT3A Overgrowth Syndrome/DOS). Somatic mutations in the DNMT3A gene are also the most common cause of clonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2971b39c011fd13e4e18717a586379c
https://doi.org/10.1038/s41467-021-24800-7
https://doi.org/10.1038/s41467-021-24800-7
Autor:
Joseph D. Dougherty, Adam W. Clemens, Jenna R. Martin, Y. Liu, Nicole M. Kirkland, Sabin A. Nettles, J. Russell Moore, Cheryl A. Hill, David F. Wozniak, Diana L. Christian, Harrison W. Gabel, Dennis Y. Wu
SummaryMutations in DNA methyltransferase 3A (DNMT3A) have been detected in autism and related disorders, but how these mutations disrupt nervous system function is unknown. Here we define the effects of neurodevelopmental disease-associated DNMT3A m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87e6b4bbf07447be55610a1a38fbe3dc
https://doi.org/10.1101/2020.07.10.195859
https://doi.org/10.1101/2020.07.10.195859
Autor:
Dennis Y. Wu, Jenna R. Martin, David F. Wozniak, Thomas Papouin, Sabin A. Nettles, Joseph D. Dougherty, Cheryl A. Hill, J. Russell Moore, Adam W. Clemens, Diana L. Christian, Y. Liu, Harrison W. Gabel, Nicole M. Kirkland
Publikováno v:
Cell reports
SUMMARY Mutations in DNA methyltransferase 3A (DNMT3A) have been detected in autism and related disorders, but how these mutations disrupt nervous system function is unknown. Here, we define the effects of DNMT3A mutations associated with neurodevelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e5e6ea4b5612b4ecf7cd96996e77df
https://doi.org/10.1016/j.celrep.2020.108416
https://doi.org/10.1016/j.celrep.2020.108416
Autor:
Harrison W. Gabel, J. Russell Moore, Guoyan Zhao, Adam W. Clemens, Dennis Y. Wu, Diana L. Christian
Publikováno v:
Mol Cell
The genomes of mammalian neurons contain uniquely high levels of non-CG DNA methylation that can be bound by the Rett syndrome protein, MeCP2, to regulate gene expression. How patterns of non-CG methylation are established in neurons and the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f0e3d5576342288cf66eb39ee09ebb
https://doi.org/10.1016/j.molcel.2019.10.033
https://doi.org/10.1016/j.molcel.2019.10.033