Zobrazeno 1 - 10
of 221
pro vyhledávání: '"Diana L Williams"'
Autor:
Khushboo Borah, Jacque-Lucca Kearney, Ruma Banerjee, Pankaj Vats, Huihai Wu, Sonal Dahale, Sunitha Manjari Kasibhatla, Rajendra Joshi, Bhushan Bonde, Olabisi Ojo, Ramanuj Lahiri, Diana L Williams, Johnjoe McFadden
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0007871 (2020)
Leprosy, caused by Mycobacterium leprae, has plagued humanity for thousands of years and continues to cause morbidity, disability and stigmatization in two to three million people today. Although effective treatment is available, the disease incidenc
Externí odkaz:
https://doaj.org/article/194597e791744d9a9caf9e9f4b498baa
Autor:
Sergio Araujo, Luiz Ricardo Goulart, Richard W Truman, Isabela Maria B Goulart, Varalakshmi Vissa, Wei Li, Masanori Matsuoka, Philip Suffys, Amanda B Fontes, Patricia S Rosa, David M Scollard, Diana L Williams
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005506 (2017)
BACKGROUND:Real-Time PCR-High Resolution Melting (qPCR-HRM) analysis has been recently described for rapid drug susceptibility testing (DST) of Mycobacterium leprae. The purpose of the current study was to further evaluate the validity, reliability,
Externí odkaz:
https://doaj.org/article/3e0ee1058b354bf29ea7faa8506a93ac
Autor:
William H Wheat, Amy L Casali, Vincent Thomas, John S Spencer, Ramanuj Lahiri, Diana L Williams, Gerald E McDonnell, Mercedes Gonzalez-Juarrero, Patrick J Brennan, Mary Jackson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 12, p e3405 (2014)
Leprosy is a curable neglected disease of humans caused by Mycobacterium leprae that affects the skin and peripheral nerves and manifests clinically in various forms ranging from self-resolving, tuberculoid leprosy to lepromatous leprosy having signi
Externí odkaz:
https://doaj.org/article/598d36f34f7c4d09a3fb396151fcbd9a
Autor:
Grace L Davis, Nashone A Ray, Ramanuj Lahiri, Thomas P Gillis, James L Krahenbuhl, Diana L Williams, Linda B Adams
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 8, p e2404 (2013)
BACKGROUND: The inability of Mycobacterium leprae to grow on axenic media has necessitated specialized techniques in order to determine viability of this organism. The purpose of this study was to develop a simple and sensitive molecular assay for de
Externí odkaz:
https://doaj.org/article/dec6ab604c7140589703845b08d5f51c
Autor:
Diana L. Williams
Publikováno v:
Br J Pharmacol
Glucagon-like peptide 1 (GLP-1) is well known as a gut hormone and also acts as a neuropeptide, produced in a discrete population of caudal brainstem neurons that project widely throughout the brain. GLP-1 receptors are expressed in many brain areas
Autor:
Shannon M. Lenz, Nashone A. Ray, Tsehaynesh Lema, J. Hunter Collins, Ruby Thapa, Selfu Girma, Marivic Balagon, Kidist Bobosha, Deanna A. Hagge, Diana L. Williams, David M. Scollard, Ramanuj Lahiri, Linda B. Adams
Publikováno v:
Frontiers in Tropical Diseases. 3
Mycobacterium leprae is a slow-growing species of mycobacteria that cannot be cultured in axenic media. This presents a number of challenges for monitoring treatment efficacy and advancing new drugs and regimens for treating leprosy. We previously de
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Mycobacterium leprae, the causative agent of leprosy, is an obligate intracellular pathogen primarily residing within host macrophages and Schwann cells. Whole genome sequencing predicts a highly degraded genome with approximately one third of the co
Autor:
Rahul Sharma, Ramanuj Lahiri, David M. Scollard, Maria Pena, Diana L. Williams, Linda B. Adams, John Figarola, Richard W. Truman
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 1, Pp 19-24 (2013)
Leprosy (also known as Hansen’s disease) is an infectious peripheral neurological disorder caused by Mycobacterium leprae that even today leaves millions of individuals worldwide with life-long disabilities. The specific mechanisms by which this ba
Externí odkaz:
https://doaj.org/article/38434564fc1144518a2a84ecd9922453
Autor:
Diana L. Williams
Publikováno v:
In Practice
Background:Fasciola hepatica is a common parasite of grazing livestock, which causes considerable economic losses through high levels of morbidity, mortality and reduced productivity. Its prevalence has increased in recent years, probably due to envi
Publikováno v:
Obesity (Silver Spring)
Objective Intermittent (INT) access to a high-fat diet (HFD) can induce excessive-intake phenotypes in rodents. This study hypothesized that impaired satiation responses contribute to elevated intake in an INT-HFD access model. Methods First, this st