Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Diana Karpman"'
Autor:
Viktor Rydberg, Sigridur Sunna Aradottir, Ann-Charlotte Kristoffersson, Naila Svitacheva, Diana Karpman
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/26a595d54f074a8eb687540ef0957a13
Autor:
Niklas Friberg, Ida Arvidsson, Ashmita Tontanahal, Ann-Charlotte Kristoffersson, Magnus Gram, Bernard S. Kaplan, Diana Karpman
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Hemolysis is a cardinal feature of hemolytic uremic syndrome (HUS) and during hemolysis excess arginase 1 is released from red blood cells. Increased arginase activity leads to reduced L-arginine, as it is converted to urea and L-
Externí odkaz:
https://doaj.org/article/8c7d034f43a8444381862106789a69c4
Autor:
Sigridur Sunna Aradottir, Ann-Charlotte Kristoffersson, Brynjar O. Jensson, Patrick Sulem, Henning Gong, Runolfur Palsson, Diana Karpman
Publikováno v:
Kidney International Reports, Vol 8, Iss 5, Pp 1097-1101 (2023)
Externí odkaz:
https://doaj.org/article/096289848014405480832f50974e9c72
Autor:
Viktor Rydberg, Sigridur Sunna Aradottir, Ann-Charlotte Kristoffersson, Naila Svitacheva, Diana Karpman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundComplement activation in atypical hemolytic uremic syndrome (aHUS), C3 glomerulonephropathy (C3G) and immune complex-mediated membranoproliferative glomerulonephritis (IC-MPGN) may be associated with rare genetic variants. Here we describe
Externí odkaz:
https://doaj.org/article/cf5e974e7ce04cb3be958bb057b9b403
Autor:
Ida Arvidsson, Ashmita Tontanahal, Karl Johansson, Ann-Charlotte Kristoffersson, Sára Kellnerová, Michael Berger, Ulrich Dobrindt, Diana Karpman
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Shiga toxin (Stx)-producing enterohemorrhagic Escherichia coli (EHEC) cause gastrointestinal infection and, in severe cases, hemolytic uremic syndrome which may lead to death. There is, to-date, no therapy for this infection. Stx induces ATP release
Externí odkaz:
https://doaj.org/article/7cfcb7e5564c459a96ee5d390e46b68a
Autor:
Ashmita Tontanahal, Vanessa Sperandio, Olga Kovbasnjuk, Sebastian Loos, Ann-Charlotte Kristoffersson, Diana Karpman, Ida Arvidsson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Shiga toxin-producing Escherichia coli O157:H7 is a virulent strain causing severe gastrointestinal infection, hemolytic uremic syndrome and death. To date there are no specific therapies to reduce progression of disease. Here we investigated the eff
Externí odkaz:
https://doaj.org/article/9fdb2f1e67434f75a93c352cb9e178c1
Autor:
Robin Vinck, Laetitia Anvi Nguyen, Mathilde Munier, Lucie Caramelle, Diana Karpman, Julien Barbier, Alain Pruvost, Jean-Christophe Cintrat, Daniel Gillet
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14611 (2022)
A recently developed inhibitor of retrograde transport, namely Retro-2.1, proved to be a potent and broad-spectrum lead in vitro against intracellular pathogens, such as toxins, parasites, intracellular bacteria and viruses. To circumvent its low aqu
Externí odkaz:
https://doaj.org/article/4d1c727497204737901a29c2a55eb4c6
Autor:
Sigridur Sunna Aradottir, Ann-Charlotte Kristoffersson, Lubka T. Roumenina, Anna Bjerre, Pavlos Kashioulis, Runolfur Palsson, Diana Karpman
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Complement factor B (FB) mutant variants are associated with excessive complement activation in kidney diseases such as atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy and membranoproliferative glomerulonephritis (MPGN). Patients with aH
Externí odkaz:
https://doaj.org/article/beb06f98da314f579d680de0c2454741
Autor:
Ingrid Lopatko Fagerström, Anne-lie Ståhl, Maria Mossberg, Ramesh Tati, Ann-Charlotte Kristoffersson, Robin Kahn, Jean-Loup Bascands, Julie Klein, Joost P. Schanstra, Mårten Segelmark, Diana Karpman
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 319-328 (2019)
Background: The complement and kallikrein-kinin systems (KKS) are activated during vascular inflammation. The aim of this study was to investigate if blockade of the KKS can affect complement activation on the endothelium during inflammation. Methods
Externí odkaz:
https://doaj.org/article/5cdcfb5b8b124e5295780a44d2d6820a
Autor:
Karl Johansson, Annie Willysson, Ann-Charlotte Kristoffersson, Ashmita Tontanahal, Daniel Gillet, Anne-lie Ståhl, Diana Karpman
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Shiga toxin is the main virulence factor of non-invasive enterohemorrhagic Escherichia coli strains capable of causing hemolytic uremic syndrome. Our group has previously shown that the toxin can reach the kidney within microvesicles where it is take
Externí odkaz:
https://doaj.org/article/a9da3b58033a4a21844c0f6a1f1cb492