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pro vyhledávání: '"Diana Karlsson"'
Modeling the regulation of the competence-evoking quorum sensing network in Streptococcus pneumoniae
Publikováno v:
Biosystems. 90:211-223
Competence for genetic transformation seems to play a fundamental role in the biology of Streptococcus pneumoniae and is believed to account for serotype switching, evolution of virulence factors, and rapid emergence of antibiotic resistance. The ini
Publikováno v:
Immunology & Cell Biology. 84:218-226
Th-cell differentiation is highly influenced by the local cytokine environment. Although cytokines such as IL-12 and IL-4 are known to polarize the Th-cell response towards Th1 or Th2, respectively, it is not known whether these cytokines instruct th
Autor:
Birger Trollfors, Erik Backhaus, Åke Örtqvist, Jessica Darenberg, Ilias Galanis, Mikael Ejdebäck, Margareta Eriksson, Carl Spindler, Diana Karlsson, Birgitta Henriques-Normark, Rune Andersson, Sarah Browall, Karin Sjöström, Pontus Naucler, Stefan Berg, Joachim Luthander, Mats Kalin
Publikováno v:
The European respiratory journal. 44(6)
Pneumococcal conjugated vaccines (PCVs) have shown protection against invasive pneumococcal disease by vaccine serotypes, but an increase in non-vaccine serotype disease has been observed. Type-specific effects on clinical manifestation need to be ex
Autor:
Diana Karlsson
Publikováno v:
Epidemiology and infection. 139(9)
SUMMARYThe worldwide increase of resistant S. pneumoniae is a growing clinical problem. In several countries, a more restrictive use of penicillin has been promoted in hope of slowing the rates of resistant pneumococci. However, the consequences of s
Publikováno v:
BMC Infectious Diseases, Vol 8, Iss 1, p 83 (2008)
BMC Infectious Diseases
BMC Infectious Diseases
Background Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide, but also a common colonizer of the upper respiratory tract. The emergence and spread of antibiotic resistant pneumococcal strains has threatened effective ther
Publikováno v:
Critical Care
Neutrophil to lymphocyte count ratio performs better than procalcitonin as a biomarker for bacteremia and severe sepsis in the emergency department