Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Diana K. Fisher"'
Autor:
Amanda M. Gillum, Xing Shen, Mahmut Miski, Terry J. Higgins, Raymond Cooper, Diana K. Fisher, Richard W. Miller
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1519-1522
Using a high throughput colorimetric bioassay three aporphine alkaloids, annonaine, nornuciferine and roemerine, were isolated and identified as the CD45 protein tyrosine phosphatase inhibitor metabolites of Rollinia ulei . The nor-aporphine alkaloid
Autor:
Roland E. Dolle, Diana K. Fisher, Ashis K. Saha, Mark A. Bobko, Terry J. Higgins, Henry R. Wolfe
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:353-356
Using fyn PTK as a template, a series of phosphopeptides 1–11 spanning in length from 1–14 amino acids was prepared. Kinetic evaluation of 1–11 suggest that CD45 does not have a strong preference for its N- or C-terminal amino acids and that ex
Autor:
Diana K. Fisher, Terry J. Higgins
Publikováno v:
Pharmaceutical Research. 11:759-763
Protein phosphatases are intimately involved in a variety of cellular processes, many of which are of interest to the pharmaceutical industry. Phosphatase assays generally employ radioisotopes, making them tedious to perform, costly, and hazardous, w