Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Diana J. Lawrence-Watt"'
Autor:
Justin R. Sharpe, Kasia Jubin, Simon Booth, Baljit Dheansa, Diana J. Lawrence-Watt, Nigel R. Jordan
Publikováno v:
Journal of Burn Care & Research. 34:e201-e208
The aim of this study was to measure the pH on the wound surface of 30 burn patients and test the hypothesis that wound surface pH is correlated to healing time and burn depth. Inclusion criteria were any adult outpatient with burn injury. Patient ag
Autor:
Christopher M. Jack, Stefan Weitzel, Nemandra A Sandiford, Konstantinos Tsitskaris, Diana J. Lawrence-Watt, Samuel Rajaratnam
Publikováno v:
HIP International. 22:184-188
Hip replacement surgery remains one of the most successful and common operations in modern orthopaedics. Many surgical approaches to the hip have been described. A potential anatomical weakness exists between the hip joint and the retroperitoneal spa
Publikováno v:
Cytotechnology. 63:655-662
Autologous keratinocytes can be used to augment cutaneous repair, such as in the treatment of severe burns and recalcitrant ulcers. Such cells can be delivered to the wound bed either as a confluent sheet of cells or in single-cell suspension. The st
Publikováno v:
Tissue Engineering Part B: Reviews. 17:71-80
Microcarriers are a versatile tool with applications across a wide range of disciplines within tissue engineering. Large numbers of cells of appropriate phenotypes are required in engineering the many different tissues of the body, and microcarriers
Autor:
Jennifer E. Morgan, Michael L. Roberts, Andrew C.G. Porter, Ian R. Graham, Diana J. Lawrence-Watt, Qi Long Lu, Kirstin Goldring, Matthew G. Dunckley, Olga Isman, George Dickson, Terence A. Partridge
Publikováno v:
Human Gene Therapy. 19:1000-1008
Chromosomal correction of dystrophin gene mutations is a most desirable therapeutic solution for Duchenne muscular dystrophy, as it allows production of the full-length dystrophin under the control of locus-specific promoters. Here we explored gene t
Autor:
Ketan Patel, Anthony Otto, Francesco Muntoni, Diana J. Lawrence-Watt, Petr Valasek, Corina Schmidt, Graham Luke, Steve Allen
Publikováno v:
Journal of Cell Science. 121:2939-2950
Satellite cells represent the stem cell population of adult skeletal muscle. The molecular mechanisms that control the proliferation of satellite cells are not well understood. In this study, we show that in response to injury, myofibres activate Wnt
Autor:
Hilary J. Pollard, Françoise Poirier, Vasilios Georgiadis, Julia Horwood, Helen Stewart, Yasemin Tavsanoglu, Kirstin Goldring, Rathi Prasad, Louise Deltour, Diana J. Lawrence-Watt
Publikováno v:
Developmental Dynamics. 236:1014-1024
Galectin-1 has been implicated in the development of skeletal muscle, being maximally expressed at the time of myofiber formation. Furthermore, in the presence of exogenous galectin-1, mononuclear myoblasts show increased fusion in vitro. In the curr
Autor:
Justin R. Sharpe, Manraj K. Phull, Diana J. Lawrence-Watt, Y.H. Martin, Gary Phillips, Judy Roxburgh, Trevor Eydmann
Publikováno v:
Journal of materials science. Materials in medicine. 24(2)
The restoration of body contours as shaped by adipose tissue remains a clinical challenge specifically in patients who have experienced loss of contour due to trauma, surgical removal of tumours or congenital abnormalities. We have developed a novel
Publikováno v:
Tissue engineering. Part A. 18(5-6)
In full-thickness injuries caused by extensive burns or penetrating traumatic injuries, the natural epidermal stem cell niche is destroyed, and wound healing occurs through migration of cells from the wound edges and wound contraction. This can lead
Publikováno v:
Glycobiology. 19(12)
Galectin-1, the prototype of a family of beta-galactoside-binding proteins, has been implicated in a wide variety of biological processes. Data presented herein show that galectin-1 stimulates monocyte migration in a dose-dependent manner but is not