Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Diana Hide"'
Autor:
Mar Gil, Lareen Khouri, Imma Raurell, Diana Rafael, Fernanda Andrade, Ibane Abasolo, Simo Schwartz, María Martínez-Gómez, María Teresa Salcedo, Juan Manuel Pericàs, Diana Hide, Mingxing Wei, Norman Metanis, Joan Genescà, María Martell
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2463 (2023)
In this study, we developed functionalized polymeric micelles (FPMs) loaded with simvastatin (FPM-Sim) as a drug delivery system to target liver sinusoidal endothelial cells (LSECs) for preserving liver function in chronic liver disease (CLD). Polyme
Externí odkaz:
https://doaj.org/article/e603b3eed6d04f5284bf5147d9e90211
Autor:
Mar Gil, Mikel Azkargorta, Carla Fuster, María Martínez-Gómez, Imma Raurell, Aurora Barberá, Juan Manuel Pericàs, Diana Hide, Felix Elortza, Joan Genescà, María Martell
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 11904 (2023)
Molecular markers of dedifferentiation of dysfunctional liver sinusoidal endothelial cells (LSEC) have not been fully elucidated. We aimed at deciphering the molecular profile of dysfunctional LSEC in different pathological scenarios. Flow cytometry
Externí odkaz:
https://doaj.org/article/ee6d01bc92974fa1b510344a9ef70a05
Autor:
Miren Bravo, Imma Raurell, Aurora Barberá, Diana Hide, Mar Gil, Federico Estrella, María Teresa Salcedo, Salvador Augustin, Joan Genescà, María Martell
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 5 (2021)
In non-alcoholic steatohepatitis (NASH), decreased nitric oxide and increased endothelin-1 (ET-1, also known as EDN1) released by sinusoidal endothelial cells (LSEC) induce hepatic stellate cell (HSC) contraction and contribute to portal hypertension
Externí odkaz:
https://doaj.org/article/797dfad6a50046d5a94c077976b32831
Autor:
Jordi Gracia‐Sancho, Nicolò Manicardi, Martí Ortega‐Ribera, Raquel Maeso‐Díaz, Sergi Guixé‐Muntet, Anabel Fernández‐Iglesias, Diana Hide, Héctor García‐Calderó, Zoe Boyer‐Díaz, Patricia C. Contreras, Alfred Spada, Jaime Bosch
Publikováno v:
Hepatology Communications, Vol 3, Iss 7, Pp 987-1000 (2019)
In cirrhosis, liver microvascular dysfunction is a key factor increasing hepatic vascular resistance to portal blood flow, which leads to portal hypertension. De‐regulated inflammatory and pro‐apoptotic processes due to chronic injury play import
Externí odkaz:
https://doaj.org/article/5e9aa8e0b22b4f6ab1c1ba7332d46118
Autor:
Fernanda Cristina de Mesquita, Sergi Guixé-Muntet, Anabel Fernández-Iglesias, Raquel Maeso-Díaz, Sergi Vila, Diana Hide, Martí Ortega-Ribera, José Luís Rosa, Juan Carlos García-Pagán, Jaime Bosch, Jarbas Rodrigues de Oliveira, Jordi Gracia-Sancho
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Hepatic stellate cells (HSC) play a key role in the development of chronic liver disease (CLD). Liraglutide, well-established in type 2 diabetes, showed anti-inflammatory and anti-oxidant properties. We evaluated the effects of liraglutide o
Externí odkaz:
https://doaj.org/article/900702cceaa04c7381a0e86421ce63a4
Autor:
Fernanda Andrade, María Mercé Roca-Melendres, Monserrat Llaguno, Diana Hide, Imma Raurell, María Martell, Sekar Vijayakumar, Mireia Oliva, Simó Schwartz, Esteban F. Durán-Lara, Diana Rafael, Ibane Abasolo
Publikováno v:
Carbohydrate polymers. 295
Local cancer treatment by in situ injections of thermo-responsive hydrogels (HG) offers several advantages over conventional systemic anti-cancer treatments. In this work, a biodegradable and multicompartmental HG composed of N-isopropylacrylamide, c
Autor:
Mar Gil, Carla Fuster, Mikel Azkargorta, Imma Raurell, Aurora Barbera, Felix Elortza, Joan Genesca, Diana Hide, María Martell
Publikováno v:
Journal of Hepatology. 77:S365-S366
Autor:
Joan Genescà, Mar Gil, Anabel Fernández-Iglesias, Miren Bravo, Diana Hide, Aurora Barberá, Salvador Augustin, María Martell, Imma Raurell, María Teresa Salcedo
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Scientific Reports
Non-alcoholic steatohepatitis (NASH) is a common chronic liver disorder in developed countries, with the associated clinical complications driven by portal hypertension (PH). PH may precede fibrosis development, probably due to endothelial dysfunctio
Autor:
Joan Genescà, Salvador Augustin, Mar Gil, María Martell, Imma Raurell, Diana Hide, Aurora Barberá, Federico Estrella, María Teresa Salcedo, Miren Bravo
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 5 (2021)
Scientia
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 5 (2021)
Scientia
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
In non-alcoholic steatohepatitis (NASH), decreased nitric oxide and increased endothelin-1 (ET-1, also known as EDN1) released by sinusoidal endothelial cells (LSEC) induce hepatic stellate cell (HSC) contraction and contribute to portal hypertension
Autor:
Diana Hide, Jordi Gracia-Sancho, Zoe Boyer-Diaz, Anabel Fernández-Iglesias, Alfred P. Spada, Raquel Maeso-Díaz, Sergi Guixé-Muntet, Nicolò Manicardi, Patricia C. Contreras, Héctor García-Calderó, Martí Ortega-Ribera, Jaime Bosch
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 3, Iss 7, Pp 987-1000 (2019)
Gracia-Sancho, Jordi; Manicardi, Nicolò; Ortega-Ribera, Martí; Maeso-Díaz, Raquel; Guixé Muntet, Sergi; Fernández-Iglesias, Anabel; Hide, Diana; García-Calderó, Héctor; Boyer-Díaz, Zoe; Contreras, Patricia C; Spada, Alfred; Bosch, Jaime (2019). Emricasan Ameliorates Portal Hypertension and Liver Fibrosis in Cirrhotic Rats Through a Hepatocyte-Mediated Paracrine Mechanism. Hepatology communications, 3(7), pp. 987-1000. 10.1002/hep4.1360
Hepatology Communications, Vol 3, Iss 7, Pp 987-1000 (2019)
Gracia-Sancho, Jordi; Manicardi, Nicolò; Ortega-Ribera, Martí; Maeso-Díaz, Raquel; Guixé Muntet, Sergi; Fernández-Iglesias, Anabel; Hide, Diana; García-Calderó, Héctor; Boyer-Díaz, Zoe; Contreras, Patricia C; Spada, Alfred; Bosch, Jaime (2019). Emricasan Ameliorates Portal Hypertension and Liver Fibrosis in Cirrhotic Rats Through a Hepatocyte-Mediated Paracrine Mechanism. Hepatology communications, 3(7), pp. 987-1000. 10.1002/hep4.1360
In cirrhosis, liver microvascular dysfunction is a key factor increasing hepatic vascular resistance to portal blood flow, which leads to portal hypertension. De-regulated inflammatory and pro-apoptotic processes due to chronic injury play important