Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Diana H. Quan"'
Autor:
Erica L. Stewart, Claudio Counoupas, Diana H. Quan, Trixie Wang, Nikolai Petrovsky, Warwick J. Britton, James A. Triccas
Publikováno v:
Vaccines, Vol 12, Iss 2, p 128 (2024)
Tuberculosis (TB), caused by Mycobacterium tuberculosis, results in approximately 1.6 million deaths annually. BCG is the only TB vaccine currently in use and offers only variable protection; however, the development of more effective vaccines is hin
Externí odkaz:
https://doaj.org/article/f4b0819b5c944be49480f1bf7d8e91f1
Publikováno v:
European Respiratory Review, Vol 31, Iss 164 (2022)
Cigarette smoke (CS) exposure is a key risk factor for both active and latent tuberculosis (TB). It is associated with delayed diagnosis, more severe disease progression, unfavourable treatment outcomes and relapse after treatment. Critically, CS exp
Externí odkaz:
https://doaj.org/article/99dfcb6ee8c547c49faf176d62996bea
Autor:
Shuxiong Chen, Diana H. Quan, Xiaonan T. Wang, Sarah Sandford, Joanna R. Kirman, Warwick J. Britton, Bernd H. A. Rehm
Publikováno v:
Nanomaterials, Vol 11, Iss 8, p 2060 (2021)
Currently available vaccines fail to provide consistent protection against tuberculosis (TB). New, improved vaccines are urgently needed for controlling the disease. The mycobacterial antigen fusions H4 (Ag85B-TB10.4) and H28 (Ag85B-TB10.4-Rv2660c) h
Externí odkaz:
https://doaj.org/article/157e85f793c74cb89093a623d6d2448a
Autor:
Gayathri Nagalingam, James A. Triccas, Nikolai Petrovsky, Warwick J. Britton, Claudio Counoupas, Rachel Pinto, Diana H. Quan
Publikováno v:
Vaccine. 39:1990-1996
The development of safe and effective adjuvants is a critical goal of vaccine development programs. In this report, we defined the immunostimulatory profile and protective effect against aerosol Mycobacterium tuberculosis infection of vaccine formula
Autor:
Ahmed H. Albariqi, Yuncheng Wang, Rachel Yoon Kyung Chang, Diana H. Quan, Xiaonan Wang, Stefanie Kalfas, John Drago, Warwick J. Britton, Hak-Kim Chan
Publikováno v:
International journal of pharmaceutics. 619
Pharmacokinetic limitations associated with oral ivermectin may limit its success as a potential COVID-19 treatment based on in vitro experiments which demonstrate antiviral efficacy against SARS-CoV-2 at high concentrations. Targeted delivery to the
Autor:
Shuxiong Chen, Diana H. Quan, Gayathri Sam, Victoria Ozberk, Xiaonan T. Wang, Peter Halfmann, Manisha Pandey, Michael F. Good, Yoshihiro Kawaoka, Warwick J. Britton, Bernd H. A. Rehm
Publikováno v:
Small. 19:2205819
Immunogenic carrier proteins such as the non-toxic diphtheria toxin variant, cross-reacting material 197 (CRM197), are widely used in subunit vaccine formulations to boost immunogenicity of chemically conjugated antigens. Conjugate vaccines are inher
Autor:
Warwick J. Britton, Joanna R. Kirman, Bernd H. A. Rehm, Xiaonan T Wang, Shuxiong Chen, Sarah Sandford, Diana H. Quan
Publikováno v:
Nanomaterials
Volume 11
Issue 8
Nanomaterials, Vol 11, Iss 2060, p 2060 (2021)
Volume 11
Issue 8
Nanomaterials, Vol 11, Iss 2060, p 2060 (2021)
Currently available vaccines fail to provide consistent protection against tuberculosis (TB). New, improved vaccines are urgently needed for controlling the disease. The mycobacterial antigen fusions H4 (Ag85B-TB10.4) and H28 (Ag85B-TB10.4-Rv2660c) h
Autor:
Sumit Kumar, Philip M. Hansbro, Vipan Kumar, Warwick J. Britton, Shalini, Laurent Kremer, Diana H. Quan, Matt D. Johansen, Clément Raynaud
Publikováno v:
Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2021, 65 (8), pp.e0001121. ⟨10.1128/AAC.00011-21⟩
Antimicrobial Agents and Chemotherapy, 2021, 65 (8), pp.e0001121. ⟨10.1128/AAC.00011-21⟩
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2021, 65 (8), pp.e0001121. ⟨10.1128/AAC.00011-21⟩
Antimicrobial Agents and Chemotherapy, 2021, 65 (8), pp.e0001121. ⟨10.1128/AAC.00011-21⟩
International audience; Tuberculosis remains a leading cause of mortality among infectious diseases worldwide, prompting the need to discover new drugs to fight this disease. We report here the design, synthesis, and antimycobacterial activity of isa
Biological and Biochemical Evaluation of Isatin-Isoniazid Hybrids as Bactericidal Candidates against
Autor:
Matt D, Johansen, Shalini, Sumit, Kumar, Clément, Raynaud, Diana H, Quan, Warwick J, Britton, Philip M, Hansbro, Vipan, Kumar, Laurent, Kremer
Publikováno v:
Antimicrob Agents Chemother
Tuberculosis remains a leading cause of mortality among infectious diseases worldwide, prompting the need to discover new drugs to fight this disease. We report here the design, synthesis, and antimycobacterial activity of isatin-mono/bis-isoniazid h
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e111782 (2014)
Tuberculosis afflicts an estimated 2 billion people worldwide and causes 1.3 million deaths annually. Chemotherapeutic solutions rely on drugs developed many years ago, with only one new therapeutic having been approved in the last 40 years. Given th
Externí odkaz:
https://doaj.org/article/32981c099fc943539bc32dd3ef2955d7