Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Diana Gazis"'
Publikováno v:
International Journal of Peptide and Protein Research. 22:525-538
In an attempt to see whether the C=O and the NH2 of CONH2 of asparagine5 and glycinamide9 are both essential for biological activity, [5-beta-cyanoalanine] oxytocin and [9-alpha-aminoacetonitrile] oxytocin have been synthesized. Each of these analogs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c24eabebabc71ba841153e5af4264ea
https://doi.org/10.1111/j.1399-3011.1983.tb02125.x
https://doi.org/10.1111/j.1399-3011.1983.tb02125.x
Publikováno v:
International Journal of Peptide and Protein Research. 19:413-419
Oxytocin was synthesized via the solid-phase method using dehydroalanine as pseudo-protecting group of the carboxyl-terminal as well as the omega-amide functions of asparagine and glutamine in endo-position. Starting with Boc-Gly-Dha-resin and using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09df60fa129b28529f9a117be721e1dd
https://doi.org/10.1111/j.1399-3011.1982.tb02623.x
https://doi.org/10.1111/j.1399-3011.1982.tb02623.x
Autor:
John D. Glass, Irving L. Schwartz, George Stavropoulos, Diana Gazis, Dimitrios Theodoropoulos
Publikováno v:
International Journal of Peptide and Protein Research. 34:353-357
Solution methods, using N-hydroxysuccinimide esters, were used to synthesize [Glu(NHNH2)4] oxytocin and [Glu(NHNH2)4, Lys8] vasopressin. In these analogs of neurohypophyseal hormones, the side-chain carboxamide function of a glutamine residue is form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c23b6ea5ceffc0dc7d63fbde37a25f8
https://doi.org/10.1111/j.1399-3011.1989.tb00701.x
https://doi.org/10.1111/j.1399-3011.1989.tb00701.x
Publikováno v:
International Journal of Peptide and Protein Research. 16:106-110
The synthesis and biological activities of [8-alpha-hydroxyisocaproic acid]oxytocin are reported. The in vivo uterine responses to [8-alpha-hydroxyisocaproic acid] oxytocin are prolonged and those to deamino-[8-alpha hydroxyisocaproic acid] oxytocin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2652dcc7b3546a98992bb9c7b60b6099
https://doi.org/10.1111/j.1399-3011.1980.tb02942.x
https://doi.org/10.1111/j.1399-3011.1980.tb02942.x
Publikováno v:
International Journal of Peptide and Protein Research. 22:398-403
The depsipeptide [8-alpha-hydroxyisocaproic acid, 9-glycolic amide]-oxytocin, which has ester linkages replacing the peptide linkages between the 7th and 8th and the 8th and 9th residues of oxytocin, has been synthesized by a (6 + 3) condensation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18673b497d93da32cc70b50b42116d32
https://doi.org/10.1111/j.1399-3011.1983.tb02108.x
https://doi.org/10.1111/j.1399-3011.1983.tb02108.x
Publikováno v:
International Journal of Peptide and Protein Research. 34:28-32
In an effort to synthesize potent vasopressin analogs containing photoreactive groups, we prepared, by solid phase synthesis, three analogs with proline or hydroxyproline substitutions in positions 4 and/or 7, lysine in positions 4 or 8, and beta-mer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed49ceace78f7ab5453e26412310f8d
https://doi.org/10.1111/j.1399-3011.1989.tb01003.x
https://doi.org/10.1111/j.1399-3011.1989.tb01003.x
Publikováno v:
International Journal of Peptide and Protein Research. 28:154-162
Tocinoic acid analogs with penicillamine in place of one or both of the cysteine residues have been studied and [1-beta-mercaptopropionic acid, 6-penicillamine] tocinoic acid (dPen6TA) and [1-beta,beta-dimethyl-beta-mercaptopropionic acid, 6-penicill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb5081964119896afd07c7d12a8dc19
https://doi.org/10.1111/j.1399-3011.1986.tb03242.x
https://doi.org/10.1111/j.1399-3011.1986.tb03242.x
Publikováno v:
International Journal of Peptide and Protein Research. 23:78-83
Substituting sarcosine or N-methylalanine for proline in the inhibitory vasopressin analogs dPAVP and d(CH2)5AVP had the following effects: 1) milk ejection and antidiuretic activities were severely depressed, 2) pressor antagonism was maintained but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ad53a90f7abcce49a653f1d3ab1fd7
https://doi.org/10.1111/j.1399-3011.1984.tb02695.x
https://doi.org/10.1111/j.1399-3011.1984.tb02695.x
Autor:
Angeliki Buku, Diana Gazis
Publikováno v:
International Journal of Peptide and Protein Research. 35:128-132
Fluorescent, photoreactive, and biotinylated analogs of vasopressin have been prepared in which one of these three groups has been attached to a reactive amino group in either position 4 or position 7. Using solid phase methodology, we have synthesiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d05b594854a7309dd1b332158fb3254
https://doi.org/10.1111/j.1399-3011.1990.tb00247.x
https://doi.org/10.1111/j.1399-3011.1990.tb00247.x
Publikováno v:
International Journal of Peptide and Protein Research. 15:279-284
[1-Alpha-Mercaptoacetic acid, 5-isoasparagine] oxytocin was synthesized to study the effects of moving the side chain carboxamide group of the amino acid residue in position 5 of oxytocin from the beta to the alpha position. The analog has an isoaspa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d104cc27a82d38bd9c220f30535be2ae
https://doi.org/10.1111/j.1399-3011.1980.tb02578.x
https://doi.org/10.1111/j.1399-3011.1980.tb02578.x