Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Diana Garcia-Moreno"'
Autor:
Ana B. Arroyo, Sylwia D. Tyrkalska, Eva Bastida-Martínez, Antonio J. Monera-Girona, Joaquín Cantón-Sandoval, Martín Bernal-Carrión, Diana García-Moreno, Montserrat Elías-Arnanz, Victoriano Mulero
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Plasmalogens are glycerophospholipids with a vinyl ether bond that confers unique properties. Recent identification of the gene encoding PEDS1, the desaturase generating the vinyl ether bond, enables evaluation of the role of plasmalogens in
Externí odkaz:
https://doaj.org/article/56ed2218fade49818990e93c3b6079a4
Autor:
Elena Martínez-Balsalobre, Jesús García-Castillo, Diana García-Moreno, Elena Naranjo-Sánchez, Miriam Fernández-Lajarín, María A. Blasco, Francisca Alcaraz-Pérez, Victoriano Mulero, María L. Cayuela
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Telomerase RNA (TERC) has a noncanonical function in myelopoiesis binding to a consensus DNA binding sequence and attracting RNA polymerase II (RNA Pol II), thus facilitating myeloid gene expression. The CR4/CR5 domain of TERC is known to pl
Externí odkaz:
https://doaj.org/article/b9be5c1113344b78b8c5918c5e096611
Autor:
Beatriz Bernal-Bermúdez, Alicia Martínez-López, Francisco J. Martínez-Morcillo, Sylwia D. Tyrkalska, Teresa Martínez-Menchón, Pablo Mesa-del-Castillo, María L. Cayuela, Victoriano Mulero, Diana García-Moreno
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Type I interferonopathies are a heterogenic group of rare diseases associated with an increase in type I interferon (IFN). The main challenge for the study of Type I interferonopathies is the lack of a well-founded animal model to better characterize
Externí odkaz:
https://doaj.org/article/92385e9bf41d445988f7b8b5009a06fb
Autor:
Lola Rodríguez‐Ruiz, Juan M Lozano‐Gil, Elena Naranjo‐Sánchez, Elena Martínez‐Balsalobre, Alicia Martínez‐López, Christophe Lachaud, Miguel Blanquer, Toan K Phung, Diana García‐Moreno, María L Cayuela, Sylwia D Tyrkalska, Ana B Pérez‐Oliva, Victoriano Mulero
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Abstract Chronic inflammatory diseases are associated with hematopoietic lineage bias, including neutrophilia and anemia. We have recently identified that the canonical inflammasome mediates the cleavage of the master erythroid transcription factor G
Externí odkaz:
https://doaj.org/article/b205befa4d104117853060fc54fa807b
Autor:
Ali Sepahi, Aurora Kraus, Jorge Galindo-Villegas, Cecilia Kelly, Diana Garcia-Moreno, Victoriano Mulero, Mar Huertas Pau, Irene Salinas
Publikováno v:
The Journal of Immunology. 200:173.15-173.15
Vertebrate olfactory sensory neurons (OSNs) are located in direct contact with the external environment and therefore they directly exposed to microorganisms such as viruses. Teleost fish have four types of OSNs, including crypt neurons, a cell type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8063494f25e81c954cf9e99e79907806
https://doi.org/10.4049/jimmunol.200.supp.173.15
https://doi.org/10.4049/jimmunol.200.supp.173.15
Autor:
Manuel Bernabé‐García, Elena Martínez‐Balsalobre, Diana García‐Moreno, Jesús García‐Castillo, Beatriz Revilla‐Nuin, Elena Blanco‐Alcaina, Victoriano Mulero, Francisca Alcaraz‐Pérez, María L. Cayuela
Publikováno v:
Molecular Oncology, Vol 15, Iss 7, Pp 1818-1834 (2021)
Telomerase reverse transcriptase (TERT) maintains telomere homeostasis, thus ensuring chromosome stability and cell proliferation. In addition, several telomere‐independent functions of human TERT have been described. In this study, we report that
Externí odkaz:
https://doaj.org/article/310687909ba642c2bc2405940c482ed2
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 708 (2023)
Melanoma is the most serious type of skin cancer. Inflammation and oxidative stress play an essential role in the development of several types of cancer, including melanoma. Although oxidative stress promotes tumor growth, once cells escape from the
Externí odkaz:
https://doaj.org/article/a1268ea393f24f1fa36967fd9818fbeb
Autor:
Francisco J. Martínez-Morcillo, Joaquín Cantón-Sandoval, Francisco J. Martínez-Navarro, Isabel Cabas, Idoya Martínez-Vicente, Joy Armistead, Julia Hatzold, Azucena López-Muñoz, Teresa Martínez-Menchón, Raúl Corbalán-Vélez, Jesús Lacal, Matthias Hammerschmidt, José C. García-Borrón, Alfonsa García-Ayala, María L. Cayuela, Ana B. Pérez-Oliva, Diana García-Moreno, Victoriano Mulero
Publikováno v:
PLoS Biology, Vol 19, Iss 11 (2021)
Several studies have revealed a correlation between chronic inflammation and nicotinamide adenine dinucleotide (NAD+) metabolism, but the precise mechanism involved is unknown. Here, we report that the genetic and pharmacological inhibition of nicoti
Externí odkaz:
https://doaj.org/article/7eee5ee7fb2a4382a2dfaadd0d7636f1
Autor:
Elena Gómez-Abenza, Sofía Ibáñez-Molero, Diana García-Moreno, Inmaculada Fuentes, Leonard I. Zon, Maria C. Mione, María L. Cayuela, Chiara Gabellini, Victoriano Mulero
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Skin cutaneous melanoma (SKCM) is the most lethal form of skin cancer and while incidence rates are declining for most cancers, they have been steadily rising for SKCM. Serine protease inhibitor, kunitz-type, 1 (SPINT1) is a type
Externí odkaz:
https://doaj.org/article/7cbb66eb49a74c728868836425bdffab
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1277 (2022)
Melanoma is the deadliest form of skin cancer, and its incidence continues to increase. In the early stages of melanoma, when the malignant cells have not spread to lymph nodes, they can be removed by simple surgery and there is usually low recurrenc
Externí odkaz:
https://doaj.org/article/a109bb8a59764179b0fbdab3052d1748