Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Diana F Lazaro"'
Autor:
Samantha L Schaffner, Zinah Wassouf, Diana F Lazaro, Mary Xylaki, Nicole Gladish, David T S Lin, Julia MacIsaac, Katia Ramadori, Thomas Hentrich, Julia M Schulze-Hentrich, Tiago F Outeiro, Michael S Kobor
Publikováno v:
Human molecular genetics 31(21), 3694-3714 (2022). doi:10.1093/hmg/ddac104
Parkinson’s disease (PD) is a neurological disorder with complex interindividual etiology that is becoming increasingly prevalent worldwide. Elevated alpha-synuclein levels can increase risk of PD and may influence epigenetic regulation of PD pathw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9453219e199f5dd697dd1004d265b214
Autor:
Blagovesta Popova, Dan Wang, Christina Pätz, Dagmar Akkermann, Diana F Lázaro, Dajana Galka, Miriam Kolog Gulko, Markus T Bohnsack, Wiebke Möbius, Katherine E Bohnsack, Tiago F Outeiro, Gerhard H Braus
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009407 (2021)
Parkinson's disease is a neurodegenerative disorder associated with misfolding and aggregation of α-synuclein as a hallmark protein. Two yeast strain collections comprising conditional alleles of essential genes were screened for the ability of each
Externí odkaz:
https://doaj.org/article/defe2fff7f0f48ecaaf115a39f833b13
Autor:
Rita Machado de Oliveira, Hugo Vicente Miranda, Laetitia Francelle, Raquel Pinho, Éva M Szegö, Renato Martinho, Francesca Munari, Diana F Lázaro, Sébastien Moniot, Patrícia Guerreiro, Luis Fonseca-Ornelas, Zrinka Marijanovic, Pedro Antas, Ellen Gerhardt, Francisco Javier Enguita, Bruno Fauvet, Deborah Penque, Teresa Faria Pais, Qiang Tong, Stefan Becker, Sebastian Kügler, Hilal Ahmed Lashuel, Clemens Steegborn, Markus Zweckstetter, Tiago Fleming Outeiro
Publikováno v:
PLoS Biology, Vol 15, Iss 4, p e1002601 (2017)
[This corrects the article DOI: 10.1371/journal.pbio.2000374.].
Externí odkaz:
https://doaj.org/article/fb415e7f10954b03bf291185f961cdfc
Autor:
Rita Machado de Oliveira, Hugo Vicente Miranda, Laetitia Francelle, Raquel Pinho, Éva M Szegö, Renato Martinho, Francesca Munari, Diana F Lázaro, Sébastien Moniot, Patrícia Guerreiro, Luis Fonseca-Ornelas, Zrinka Marijanovic, Pedro Antas, Ellen Gerhardt, Francisco Javier Enguita, Bruno Fauvet, Deborah Penque, Teresa Faria Pais, Qiang Tong, Stefan Becker, Sebastian Kügler, Hilal Ahmed Lashuel, Clemens Steegborn, Markus Zweckstetter, Tiago Fleming Outeiro
Publikováno v:
PLoS Biology, Vol 15, Iss 3, p e2000374 (2017)
Sirtuin genes have been associated with aging and are known to affect multiple cellular pathways. Sirtuin 2 was previously shown to modulate proteotoxicity associated with age-associated neurodegenerative disorders such as Alzheimer and Parkinson dis
Externí odkaz:
https://doaj.org/article/989eaa37ca2a44718ed354a73c818f4e
Autor:
Alexandra Kleinknecht, Blagovesta Popova, Diana F Lázaro, Raquel Pinho, Oliver Valerius, Tiago F Outeiro, Gerhard H Braus
Publikováno v:
PLoS Genetics, Vol 12, Iss 6, p e1006098 (2016)
Parkinson´s disease (PD) is characterized by the presence of proteinaceous inclusions called Lewy bodies that are mainly composed of α-synuclein (αSyn). Elevated levels of oxidative or nitrative stresses have been implicated in αSyn related toxic
Externí odkaz:
https://doaj.org/article/faf775e093e24380b82b2f7f22777c03
Autor:
Diana F Lázaro, Eva F Rodrigues, Ramona Langohr, Hedieh Shahpasandzadeh, Thales Ribeiro, Patrícia Guerreiro, Ellen Gerhardt, Katharina Kröhnert, Jochen Klucken, Marcos D Pereira, Blagovesta Popova, Niels Kruse, Brit Mollenhauer, Silvio O Rizzoli, Gerhard H Braus, Karin M Danzer, Tiago F Outeiro
Publikováno v:
PLoS Genetics, Vol 10, Iss 11, p e1004741 (2014)
Aggregation of alpha-synuclein (ASYN) in Lewy bodies and Lewy neurites is the typical pathological hallmark of Parkinson's disease (PD) and other synucleinopathies. Furthermore, mutations in the gene encoding for ASYN are associated with familial and
Externí odkaz:
https://doaj.org/article/6f0d371ab8a34e379f185ecad802768c