Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Diana E. Ramirez-Ardila"'
Autor:
Diana E. Ramirez-Ardila, Kirsten Ruigrok-Ritstier, Jean C. Helmijr, Maxime P. Look, Steven van Laere, Luc Dirix, Els M.J.J. Berns, Maurice P.H.M. Jansen
Publikováno v:
Molecular Oncology, Vol 10, Iss 8, Pp 1363-1373 (2016)
Background PIK3CA is the most frequent somatic mutated oncogene in estrogen receptor (ER) positive breast cancer. We previously observed an association between PIK3CA genotype and aromatase inhibitors (AI) treatment outcome. This study now evaluates
Externí odkaz:
https://doaj.org/article/8ebe2c3f82f54bf49412c8044bd74e36
Autor:
Steven Van Laere, Maurice P.H.M. Jansen, Diana E. Ramirez-Ardila, Els M.J.J. Berns, Maxime P. Look, Jean C. A. Helmijr, Kirsten Ruigrok-Ritstier, Luc Dirix
Publikováno v:
Molecular Oncology, 10(8), 1363-1373. John Wiley & Sons Ltd.
Molecular Oncology
Molecular Oncology
Background PIK3CA is the most frequent somatic mutated oncogene in estrogen receptor ( ER ) positive breast cancer. We previously observed an association between PIK3CA genotype and aromatase inhibitors (AI) treatment outcome. This study now evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67cbd9facc54dc1c952b1e68787d0060
https://doi.org/10.1016/j.molonc.2016.07.004
https://doi.org/10.1016/j.molonc.2016.07.004
Autor:
Els M.J.J. Berns, Jean A. Helmijr, Maurice P.H.M. Jansen, A. Mieke Timmermans, Diana E. Ramirez-Ardila, John W.M. Martens
Publikováno v:
Translational Oncology, 10(5), 854-867. Neoplasia Press
Translational Oncology, Vol 10, Iss 5, Pp 854-866 (2017)
Translational Oncology
Translational Oncology, Vol 10, Iss 5, Pp 854-866 (2017)
Translational Oncology
INTRODUCTION: While mutations in PIK3CA are most frequently (45%) detected in luminal breast cancer, downstream PI3K/AKT/mTOR pathway activation is predominantly observed in the basal subtype. The aim was to identify proteins activated in PIK3CA muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226e5b6c308e6b8a0455eac596957065
https://pure.eur.nl/en/publications/6cb50816-8f2b-4d93-a4b1-31fa0927b1fb
https://pure.eur.nl/en/publications/6cb50816-8f2b-4d93-a4b1-31fa0927b1fb
Autor:
Stefan Sleijfer, Diana E. Ramirez-Ardila, Maurice P.H.M. Jansen, John A. Foekens, Steven Van Laere, Paul N. Span, Els M.J.J. Berns, Kirsten Ruigrok-Ritstier, Jean C. A. Helmijr, Sabine C. Linn, Irene Lurkin, Luc Dirix, Maxime P. Look, Fred C.G.J. Sweep
Publikováno v:
Breast Cancer Research and Treatment, 139, 39-49
Breast cancer research and treatment
Breast Cancer Research and Treatment, 139, 1, pp. 39-49
Breast Cancer Research and Treatment, 139(1), 39-49. Springer New York
Breast cancer research and treatment
Breast Cancer Research and Treatment, 139, 1, pp. 39-49
Breast Cancer Research and Treatment, 139(1), 39-49. Springer New York
Item does not contain fulltext PIK3CA mutations occur frequently in breast cancer, predominantly in exons 9 and 20. The aim of this retrospective study is to evaluate the PIK3CA mutation status for its relationship with prognosis and first-line endoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb625c505ea2949de918b2f0c76fdb8
http://hdl.handle.net/2066/118544
http://hdl.handle.net/2066/118544
Autor:
Marian van Fessem, Ron H.N. van Schaik, Els M.J.J. Berns, Winand N.M. Dinjens, Maxime P. Look, Niels M.G. Krol, Stefan Sleijfer, Ronald van Marion, Irene Lurkin, Kim Monkhorst, Marion Meijer van Gelder, Marcel Smid, Anita Trapman, Jean C. A. Helmijr, Diana E. Ramirez-Ardila, Corine M. Beaufort, John A. Foekens, Ellen C. Zwarthoff, John W.M. Martens, Maurice P.H.M. Jansen
Publikováno v:
Cancer Research. 75:P4-02
Background: Evaluation of cell-free DNA (cfDNA) is a very attractive tool to serve as "liquid biopsy" to define and establish mutational changes in circulating tumor DNA (ctDNA) non-invasively during therapy. Aim: To identify tumor specific mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9050f8fc84b9485c3cd8d877cd9b2687
https://doi.org/10.1158/1538-7445.sabcs14-p4-02-02
https://doi.org/10.1158/1538-7445.sabcs14-p4-02-02