Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Diana E. Jaalouk"'
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Cancer continues to present a substantial global health challenge, with its incidence and mortality rates persistently reflecting its significant impact. The emergence of precision oncology has provided a breakthrough in targeting oncogenic drivers p
Externí odkaz:
https://doaj.org/article/4ca268b506024cd89023bbdcae37a0fd
Exploring the Crosstalk Between LMNA and Splicing Machinery Gene Mutations in Dilated Cardiomyopathy
Autor:
Hind C. Zahr, Diana E. Jaalouk
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Mutations in the LMNA gene, which encodes for the nuclear lamina proteins lamins A and C, are responsible for a diverse group of diseases known as laminopathies. One type of laminopathy is Dilated Cardiomyopathy (DCM), a heart muscle disease characte
Externí odkaz:
https://doaj.org/article/36e584e9832641a89373dbbbf411c6bf
Autor:
Renata Pasqualini, Wadih Arap, Erkki Koivunen, George A. Calin, Jorge E. Cortes, Hagop M. Kantarjian, Susan O'Brien, Amado J. Zurita, Cecilia Rietz, Marina Cardó-Vila, Wouter H.P. Driessen, Akihiko Kuniyasu, Yan Sun, Laura Bover, Carlos Bueso-Ramos, Diana E. Jaalouk, Katja Karjalainen
Supplemental Figure 1. Cell surface expression of IL-11R in AML patient derived samples and hematopoietic cells from healthy bone marrow as analyzed by flow cytometry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afe52ab9f88cbc8f848df46f9be1973
https://doi.org/10.1158/1078-0432.22457781
https://doi.org/10.1158/1078-0432.22457781
Autor:
Renata Pasqualini, Wadih Arap, Erkki Koivunen, George A. Calin, Jorge E. Cortes, Hagop M. Kantarjian, Susan O'Brien, Amado J. Zurita, Cecilia Rietz, Marina Cardó-Vila, Wouter H.P. Driessen, Akihiko Kuniyasu, Yan Sun, Laura Bover, Carlos Bueso-Ramos, Diana E. Jaalouk, Katja Karjalainen
Supplemental Table 1. Features of synthesized analogs of BMTP-11 for drug-lead optimization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c5291e96a286cefc60d9c7ee0cd1f8
https://doi.org/10.1158/1078-0432.22457769
https://doi.org/10.1158/1078-0432.22457769
Autor:
Renata Pasqualini, Wadih Arap, Erkki Koivunen, George A. Calin, Jorge E. Cortes, Hagop M. Kantarjian, Susan O'Brien, Amado J. Zurita, Cecilia Rietz, Marina Cardó-Vila, Wouter H.P. Driessen, Akihiko Kuniyasu, Yan Sun, Laura Bover, Carlos Bueso-Ramos, Diana E. Jaalouk, Katja Karjalainen
Purpose: The IL11 receptor (IL11R) is an established molecular target in primary tumors of bone, such as osteosarcoma, and in secondary bone metastases from solid tumors, such as prostate cancer. However, its potential role in management of hematopoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b233b1624b24723fc85d2ae6717a5eeb
https://doi.org/10.1158/1078-0432.c.6523689.v1
https://doi.org/10.1158/1078-0432.c.6523689.v1
Autor:
Renata Pasqualini, Wadih Arap, Erkki Koivunen, George A. Calin, Jorge E. Cortes, Hagop M. Kantarjian, Susan O'Brien, Amado J. Zurita, Cecilia Rietz, Marina Cardó-Vila, Wouter H.P. Driessen, Akihiko Kuniyasu, Yan Sun, Laura Bover, Carlos Bueso-Ramos, Diana E. Jaalouk, Katja Karjalainen
Supplemental Figure 3. Drug activity of BMTP-11 and BMTP#4 on a panel of established leukemia and lymphoma cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407d760b0e8f320ca5df7d83737e63e5
https://doi.org/10.1158/1078-0432.22457775
https://doi.org/10.1158/1078-0432.22457775
Autor:
Renata Pasqualini, Wadih Arap, Erkki Koivunen, George A. Calin, Jorge E. Cortes, Hagop M. Kantarjian, Susan O'Brien, Amado J. Zurita, Cecilia Rietz, Marina Cardó-Vila, Wouter H.P. Driessen, Akihiko Kuniyasu, Yan Sun, Laura Bover, Carlos Bueso-Ramos, Diana E. Jaalouk, Katja Karjalainen
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42445d9bb00468c934352d98a6481f09
https://doi.org/10.1158/1078-0432.22457772.v1
https://doi.org/10.1158/1078-0432.22457772.v1
Autor:
Renata Pasqualini, Wadih Arap, Erkki Koivunen, George A. Calin, Jorge E. Cortes, Hagop M. Kantarjian, Susan O'Brien, Amado J. Zurita, Cecilia Rietz, Marina Cardó-Vila, Wouter H.P. Driessen, Akihiko Kuniyasu, Yan Sun, Laura Bover, Carlos Bueso-Ramos, Diana E. Jaalouk, Katja Karjalainen
Supplemental Figure 2. Cell membrane and cytoplasmic expression of IL-11R.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61d03b914c96651b8ebfb951a2b7085
https://doi.org/10.1158/1078-0432.22457778.v1
https://doi.org/10.1158/1078-0432.22457778.v1
Autor:
Wadih Arap, Renata Pasqualini, Reinier O. Schlingemann, Johanna Lahdenranta, Jessica Sun, Michael G. Ozawa, Diana E. Jaalouk
For two decades, the antigen recognized by the Pathologische Anatomie Leiden-Endothelium (PAL-E) monoclonal antibody, a standard vascular endothelial cell marker, has remained elusive. Here, we used a combinatorial phage display–based approach (“
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::946e161625795a88d28c0fbbcb084fe2
https://doi.org/10.1158/0008-5472.c.6496668
https://doi.org/10.1158/0008-5472.c.6496668
Autor:
Renata Pasqualini, Wadih Arap, Edward A. Sausville, Susan L. Holbeck, Dominic A. Scudiero, Akihiko Kunyiasu, Fernanda I. Staquicini, Glauco R. Souza, Catherine A. Moya, Michael G. Ozawa, Diana E. Jaalouk, Ricardo J. Giordano, Marina Cardó-Vila, Johanna Lahdenranta, Kim-Anh Do, Amado J. Zurita, Jessica Sun, Laura Bover, Mikhail G. Kolonin
Supplementary Figure S1 from Ligand-Directed Surface Profiling of Human Cancer Cells with Combinatorial Peptide Libraries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb8227a3b68cdb014ccf2320b524ad6
https://doi.org/10.1158/0008-5472.22364703
https://doi.org/10.1158/0008-5472.22364703