Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Diana Drago"'
Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models
Autor:
Ilaria Marrocco, Donatella Romaniello, Itay Vaknin, Diana Drago‐Garcia, Roni Oren, Mary Luz Uribe, Nishanth Belugali Nataraj, Soma Ghosh, Raya Eilam, Tomer‐Meir Salame, Moshit Lindzen, Yosef Yarden
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp 1-18 (2021)
Abstract Some antibacterial therapies entail sequential treatments with different antibiotics, but whether this approach is optimal for anti‐cancer tyrosine kinase inhibitors (TKIs) remains open. EGFR mutations identify lung cancer patients who can
Externí odkaz:
https://doaj.org/article/f40e6d84396d426eb6294535a2d589ba
Autor:
Swati Srivastava, Nishanth Belugali Nataraj, Arunachalam Sekar, Soma Ghosh, Chamutal Bornstein, Diana Drago-Garcia, Lee Roth, Donatella Romaniello, Ilaria Marrocco, Eyal David, Yuval Gilad, Mattia Lauriola, Ron Rotkopf, Adi Kimchi, Yuya Haga, Yasuo Tsutsumi, Olivier Mirabeau, Didier Surdez, Andrei Zinovyev, Olivier Delattre, Heinrich Kovar, Ido Amit, Yosef Yarden
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 104-117.e4 (2019)
Summary: The glucocorticoid receptor (GR) acts as a ubiquitous cortisol-dependent transcription factor (TF). To identify co-factors, we used protein-fragment complementation assays and found that GR recognizes FLI1 and additional ETS family proteins,
Externí odkaz:
https://doaj.org/article/47075bdf8b9148dfa3ecd25a83e31946
Autor:
Guillermo de Anda-Jáuregui, Jesús Espinal-Enríquez, Diana Drago-García, Enrique Hernández-Lemus
Publikováno v:
International Journal of Genomics, Vol 2018 (2018)
Alterations to transcriptional regulation are an important factor in breast cancer. Noncoding RNA, such as microRNA (miR), have very influential roles in the transcriptional regulation of genes. Transcriptional regulation can be successfully modeled
Externí odkaz:
https://doaj.org/article/acd1061284ec4e2486be27f92a3b8818
Autor:
Yosef Yarden, Eytan Ruppin, Gad Getz, Aviv Regev, Joan S. Brugge, Rami I. Aqeilan, Trever G. Bivona, Laxmi Parida, Stefan Wiemann, Jideofor Ezike, Collin M. Blakely, Moshe Oren, Andrea Ardizzoni, Michelangelo Fiorentino, Mattia Lauriola, Brian P. Danysh, Diana Drago-Garcia, Youngmin Chung, Suvendu Giri, Arunachalam Sekar, Wei Wu, D. Lucas Kerr, Alexander Brandis, Sanju Sinha, Welles Robinson, Simone Borgoni, Rishita Chatterjee, Aakanksha Verma, Arturo Simoni-Nieves, Soma Ghosh, Rainer Will, Saptaparna Mukherjee, Moshit Lindzen, Sara Oster, Yaara Oren, Benny Zhitomirsky, Joo Sang Lee, Nishanth Belugali Nataraj, Ashish Noronha
Anticancer therapies have been limited by the emergence of mutations and other adaptations. In bacteria, antibiotics activate the SOS response, which mobilizes error-prone factors that allow for continuous replication at the cost of mutagenesis. We i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90156dccca93cef0832f1138ce45eef
https://doi.org/10.1158/2159-8290.c.6549711
https://doi.org/10.1158/2159-8290.c.6549711
Autor:
Yosef Yarden, Eytan Ruppin, Gad Getz, Aviv Regev, Joan S. Brugge, Rami I. Aqeilan, Trever G. Bivona, Laxmi Parida, Stefan Wiemann, Jideofor Ezike, Collin M. Blakely, Moshe Oren, Andrea Ardizzoni, Michelangelo Fiorentino, Mattia Lauriola, Brian P. Danysh, Diana Drago-Garcia, Youngmin Chung, Suvendu Giri, Arunachalam Sekar, Wei Wu, D. Lucas Kerr, Alexander Brandis, Sanju Sinha, Welles Robinson, Simone Borgoni, Rishita Chatterjee, Aakanksha Verma, Arturo Simoni-Nieves, Soma Ghosh, Rainer Will, Saptaparna Mukherjee, Moshit Lindzen, Sara Oster, Yaara Oren, Benny Zhitomirsky, Joo Sang Lee, Nishanth Belugali Nataraj, Ashish Noronha
Supplementary Figure from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b3d798497aa0ca157a505f562f91a6
https://doi.org/10.1158/2159-8290.22541643.v1
https://doi.org/10.1158/2159-8290.22541643.v1
Autor:
Yosef Yarden, Eytan Ruppin, Gad Getz, Aviv Regev, Joan S. Brugge, Rami I. Aqeilan, Trever G. Bivona, Laxmi Parida, Stefan Wiemann, Jideofor Ezike, Collin M. Blakely, Moshe Oren, Andrea Ardizzoni, Michelangelo Fiorentino, Mattia Lauriola, Brian P. Danysh, Diana Drago-Garcia, Youngmin Chung, Suvendu Giri, Arunachalam Sekar, Wei Wu, D. Lucas Kerr, Alexander Brandis, Sanju Sinha, Welles Robinson, Simone Borgoni, Rishita Chatterjee, Aakanksha Verma, Arturo Simoni-Nieves, Soma Ghosh, Rainer Will, Saptaparna Mukherjee, Moshit Lindzen, Sara Oster, Yaara Oren, Benny Zhitomirsky, Joo Sang Lee, Nishanth Belugali Nataraj, Ashish Noronha
Supplementary Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e7bdbe0faeb9783a3dfad67e1dd091
https://doi.org/10.1158/2159-8290.22541646.v1
https://doi.org/10.1158/2159-8290.22541646.v1
Autor:
Yosef Yarden, Yasuo Tsutsumi, Stefan Wiemann, Suvendu Giri, Moshit Lindzen, Simone Borgoni, Diana Drago-Garcia, Arunachalam Sekar, Nishanth Belugali Nataraj, Mary Luz Uribe, Ashish Noronha, Ilaria Marrocco, Yuya Haga
Lung cancers driven by mutant forms of EGFR invariably develop resistance to kinase inhibitors, often due to secondary mutations. Here we describe an unconventional mechanism of resistance to dacomitinib, a newly approved covalent EGFR kinase inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c2f22cb69147f185d8a21e6f9abc01
https://doi.org/10.1158/0008-5472.c.6513052.v1
https://doi.org/10.1158/0008-5472.c.6513052.v1
Autor:
Yosef Yarden, Yasuo Tsutsumi, Stefan Wiemann, Suvendu Giri, Moshit Lindzen, Simone Borgoni, Diana Drago-Garcia, Arunachalam Sekar, Nishanth Belugali Nataraj, Mary Luz Uribe, Ashish Noronha, Ilaria Marrocco, Yuya Haga
Supplementary Excel File 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70875629c5871ca720f2d40058f0a5cc
https://doi.org/10.1158/0008-5472.22428517.v1
https://doi.org/10.1158/0008-5472.22428517.v1
Autor:
Yosef Yarden, Yasuo Tsutsumi, Stefan Wiemann, Suvendu Giri, Moshit Lindzen, Simone Borgoni, Diana Drago-Garcia, Arunachalam Sekar, Nishanth Belugali Nataraj, Mary Luz Uribe, Ashish Noronha, Ilaria Marrocco, Yuya Haga
Supplementary Figures 1~11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7998034869daef58da0e51bda9132e0
https://doi.org/10.1158/0008-5472.22428526
https://doi.org/10.1158/0008-5472.22428526
Autor:
Yosef Yarden, Yasuo Tsutsumi, Stefan Wiemann, Suvendu Giri, Moshit Lindzen, Simone Borgoni, Diana Drago-Garcia, Arunachalam Sekar, Nishanth Belugali Nataraj, Mary Luz Uribe, Ashish Noronha, Ilaria Marrocco, Yuya Haga
Supplementary Excel File 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c07475830f2c0b6e01ce2d5d642de5b
https://doi.org/10.1158/0008-5472.22428520
https://doi.org/10.1158/0008-5472.22428520