Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Diana Cepeda"'
Autor:
Charles Spruck, Olle Sangfelt, Martin Widschwendter, Steven I. Reed, Dan Grander, Hans Nordgren, Per Sangfelt, Fredrik Petersson, Susanne Egyhazi, Johan Hansson, Mohammad Reza Zali, Babak Noori Nayer, Sepideh Zabihi Nejad, Markus Dagnell, Martin Corcoran, Elisabeth Mueller-Holzner, Christian Marth, Dimitra Dofou, Heidi Fiegl, Diana Cepeda, Alena Maljukova, Kathleen Klotz, Sophia Apostolidou, Natalie von der Lehr, Dahui Sun, Shahab Akhoondi
The ubiquitin-proteasome system is a major regulatory pathway of protein degradation and plays an important role in cellular division. Fbxw7 (or hCdc4), a member of the F-box family of proteins, which are substrate recognition components of the multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f23907af830a4be9a61f44daaab6df85
https://doi.org/10.1158/0008-5472.c.6496770
https://doi.org/10.1158/0008-5472.c.6496770
Autor:
Charles Spruck, Olle Sangfelt, Martin Widschwendter, Steven I. Reed, Dan Grander, Hans Nordgren, Per Sangfelt, Fredrik Petersson, Susanne Egyhazi, Johan Hansson, Mohammad Reza Zali, Babak Noori Nayer, Sepideh Zabihi Nejad, Markus Dagnell, Martin Corcoran, Elisabeth Mueller-Holzner, Christian Marth, Dimitra Dofou, Heidi Fiegl, Diana Cepeda, Alena Maljukova, Kathleen Klotz, Sophia Apostolidou, Natalie von der Lehr, Dahui Sun, Shahab Akhoondi
Supplementary Table 1 from FBXW7/hCDC4 Is a General Tumor Suppressor in Human Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393ecf68db5a7048c1c006ed29fe6c1b
https://doi.org/10.1158/0008-5472.22371378.v1
https://doi.org/10.1158/0008-5472.22371378.v1
Autor:
Kelly Hanna, Julio Nieves, Christine Dowd, Kristina Oresic Bender, Pallavi Sharma, Baljit Singh, Mark Renz, James N. Ver Hoeve, Diana Cepeda, Claire M. Gelfman, Brigit E. Riley, Ruslan N. Grishanin
Publikováno v:
Molecular Therapy.
Autor:
Stefan Grotegut, Daniel Klevebring, Helen Nilsson, Dahui Sun, Sanjay Navani, Fredrik Pontén, Karin Jirström, Juha Rantala, Mikael Lerner, Michael L. Nielsen, Kristina Magnusson, Vanessa Soto Cerrato, Mathias Uhlén, Salah Mahmoudi, Aldwin Suryo Rahmanto, Martin Widschwendter, Charles Spruck, Francesc Viñals, Cristina Al-Khalili Szigyarto, Erik Fredlund, Hamid Sharifi, Dan Grandér, James A. Wohlschlegel, Diana Cepeda, Nimesh Bhaskaran, Lars-Gunnar Larsson, Olle Sangfelt, Siti Mariam Zakaria, Hwee-Fang Ng, Alena Malyukova
Publikováno v:
EMBO Molecular Medicine. 5:1067-1086
SCF (Skp1/Cul1/F-box) ubiquitin ligases act as master regulators of cellular homeostasis by targeting key proteins for ubiquitylation. Here, we identified a hitherto uncharacterized F-box protein, FBXO28 that controls MYC-dependent transcription by n
Autor:
Ning Ma, Ioannis Karakikes, Ilanit Itzhaki, Diana Cepeda, Elena Matsa, Mohamed Ameen, Rajani Shrestha, Matthew H. Porteus, Nicole A. Woo, Timon Seeger, Haodi Wu, Kitchener D. Wilson, Joseph C. Wu, Vittavat Termglinchan, Ayal Hendel, Sebastian Diecke, Vittorio Sebastiano, Ning-Yi Shao, Jae Cheol Lee
Publikováno v:
Circulation research. 120(10)
Rationale: Targeted genetic engineering using programmable nucleases such as transcription activator–like effector nucleases (TALENs) is a valuable tool for precise, site-specific genetic modification in the human genome. Objective: The emergence o
Publikováno v:
Cell Cycle. 7:1075-1082
The ubiquitin-mediated turnover of cyclin E is regulated by phosphorylation and the activity of the ubiquitin ligase SCF(Cdc4) (also known as SCF(Fbw7)). In 293A cells, SCF complexes containing two different Cdc4 isoforms, alpha and gamma, are requir
Autor:
Shahab, Akhoondi, Dahui, Sun, Natalie, von der Lehr, Sophia, Apostolidou, Kathleen, Klotz, Alena, Maljukova, Diana, Cepeda, Heidi, Fiegl, Dimitra, Dafou, Dimitra, Dofou, Christian, Marth, Elisabeth, Mueller-Holzner, Martin, Corcoran, Markus, Dagnell, Sepideh Zabihi, Nejad, Babak Noori, Nayer, Mohammad Reza, Zali, Johan, Hansson, Susanne, Egyhazi, Fredrik, Petersson, Per, Sangfelt, Hans, Nordgren, Dan, Grander, Steven I, Reed, Martin, Widschwendter, Olle, Sangfelt, Charles, Spruck
Publikováno v:
Cancer Research. 67:9006-9012
The ubiquitin-proteasome system is a major regulatory pathway of protein degradation and plays an important role in cellular division. Fbxw7 (or hCdc4), a member of the F-box family of proteins, which are substrate recognition components of the multi
Autor:
Joanna Wysocka, Kin Fai Au, Wing Hung Wong, Jonathan Davila, Jun Cui, Mark Wossidlo, Renee A. Reijo Pera, Vittorio Sebastiano, Diana Cepeda, Edward J. Grow, Moritz Mall, Jens Durruthy-Durruthy
Publikováno v:
Nature genetics. 48(1)
Long intergenic noncoding RNAs (lincRNAs) are derived from thousands of loci in mammalian genomes and are frequently enriched in transposable elements (TEs). Although families of TE-derived lincRNAs have recently been implicated in the regulation of
Publikováno v:
Molecular Therapy. 24:S240-S241
Introduction: Gene therapy studies in vivo using animal models provide critical information regarding vector specificity, therapeutic efficacy, and safety. However, long durations to observe transgene expression, high degree of variability between an
Publikováno v:
Experimental cell research. 315(11)
E-type cyclins (E1 and E2) regulate the S phase program in the mammalian cell division cycle. Expression of cyclin E1 and E2 is frequently deregulated in a variety of cancer types and a wealth of experimental evidence supports an oncogenic role of th