Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Diana C. Yánez"'
Autor:
Diana C. Yánez, Ching-In Lau, Eleftheria Papaioannou, Mira M. Chawda, Jasmine Rowell, Susan Ross, Anna Furmanski, Tessa Crompton
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Foxa2, a member of the Forkhead box (Fox) family of transcription factors, plays an important role in the regulation of lung function and lung tissue homeostasis. FOXA2 expression is reduced in the lung and airways epithelium of asthmatic patients an
Externí odkaz:
https://doaj.org/article/411a3068191e427ea24ae234c254d6a4
Autor:
Diana C. Yánez, Eleftheria Papaioannou, Mira M. Chawda, Jasmine Rowell, Susan Ross, Ching-In Lau, Tessa Crompton
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Allergic asthma is a common inflammatory airway disease in which Th2 immune response and inflammation are thought to be triggered by inhalation of environmental allergens. Many studies using mouse models and human tissues and genome-wide association
Externí odkaz:
https://doaj.org/article/52cdf4f55f4a447bb6f4d6b8242eaacb
Publikováno v:
Immunology
Summary Interferon‐inducible transmembrane (IFITM) proteins are a family of small homologous proteins, localized in the plasma and endolysosomal membranes, which confer cellular resistance to many viruses. In addition, several distinct functions ha
Publikováno v:
The FEBS journalReferences. 289(24)
Epithelial barrier tissues such as the skin and airway form an essential interface between the mammalian host and its external environment. These physical barriers are crucial to prevent damage and disease from environmental insults and allergens. Fa
Autor:
Susan Ross, Diana C. Yánez, Ching-In Lau, Jasmine Rowell, Mira Manilal Chawda, Eleftheria Papaioannou, Tessa Crompton
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Allergic asthma is a common inflammatory airway disease in which Th2 immune response and inflammation are thought to be triggered by inhalation of environmental allergens. Many studies using mouse models and human tissues and genome-wide association
Autor:
Paul M. Maciocia, Patrycja A. Wawrzyniecka, Nicola C. Maciocia, Amy Burley, Thaneswari Karpanasamy, Sam Devereaux, Malika Hoekx, David O’Connor, Theresa Leon, Tanya Rapoz-D’Silva, Rachael Pocock, Sunniyat Rahman, Giuseppe Gritti, Diana C. Yánez, Susan Ross, Tessa Crompton, Owen Williams, Lydia Lee, Martin A. Pule, Marc R. Mansour
Publikováno v:
Blood. 140(1)
T cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy of immature T lymphocytes, associated with higher rates of induction failure compared with those in B cell acute lymphoblastic leukemia. The potent immunotherapeutic approaches a
Autor:
Ching-In Lau, Susan Ross, Anisha Solanki, Jasmine Rowell, Masahiro Ono, Diana C. Yánez, Tessa Crompton
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
During positive selection at the transition from CD4+CD8+ double-positive (DP) to single-positive (SP) thymocyte, TCR signalling results in appropriate MHC restriction and signals for survival and progression. We show that the pioneer transcription f
Autor:
Anisha, Solanki, Diana C, Yánez, Ching-In, Lau, Jasmine, Rowell, Alessandro, Barbarulo, Susan, Ross, Hemant, Sahni, Tessa, Crompton
Publikováno v:
Development (Cambridge, England). 147(19)
Pre-T-cell receptor (TCR) signal transduction is required for developing thymocytes to differentiate from CD4
Autor:
Ching-In Lau, Jasmine Rowell, Hemant Sahni, Susan Ross, Anisha Solanki, Diana C. Yánez, Alessandro Barbarulo, Tessa Crompton
Publikováno v:
Development.
Pre-TCR signal transduction is required for developing thymocytes to differentiate from CD4-CD8- double negative (DN) to CD4+CD8+ double positive (DP) cell. Notch signalling is required for T-cell fate specification and must be maintained throughout
Publikováno v:
Journal of Leukocyte Biology
Hh/Gli signals are received by multiple pulmonary and immune cell types in response to allergen inhalation in vivo; this autocrine/paracrine activation enhances Th2 immune responses.
The pathophysiology of allergic asthma is driven by Th2 immune
The pathophysiology of allergic asthma is driven by Th2 immune