Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Diana C. Reeves"'
Autor:
Chris H. Senanayake, Carl A. Busacca, Diana C. Reeves, Jinghua Xu, Xingzhong Zeng, Vittorio Farina, Magnus C. Eriksson
Publikováno v:
Synlett. 29:1455-1460
DBU as base is key in a practical modified Guareschi–Thorpe cyclization of β-keto esters and 2-cyanoacetamide to allow the synthesis of substituted pyridones in good to excellent yields. The chlorination of DBU salts of pyridones with POCl3 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::227b8fd44e15aec459696f0b2d51f6dc
https://doi.org/10.1055/s-0037-1609685
https://doi.org/10.1055/s-0037-1609685
Autor:
Nelu Grinberg, Marc-André Poupart, Jon C. Lorenz, Bo Qu, Nizar Haddad, Nina C. Gonnella, Shengli Ma, Nathan K. Yee, Wenjun Tang, Jiang-Ping Wu, Youla S. Tsantrizos, Wenjie Li, Joe Gao, Kanwar Sidhu, June Wang, Nitinchandra D. Patel, Sonia Rodriguez, Sanjit Sanyal, Heewon Lee, Yongda Zhang, Carl A. Busacca, Diana C. Reeves, Bruce Z. Lu, Keith R. Fandrick, Chris H. Senanayake
Publikováno v:
Angewandte Chemie. 127:7250-7254
A practical and efficient synthesis of a complex chiral atropisomeric HIV integrase inhibitor has been accomplished. The combination of a copper-catalyzed acylation along with the implementation of the BI-DIME ligands for a ligand-controlled Suzuki c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d20ec4749c7a46e4ef82931f7fe303e
https://doi.org/10.1002/ange.201501575
https://doi.org/10.1002/ange.201501575
Autor:
Wenjun Tang, Jonathan T. Reeves, Christian Harcken, Heewon Lee, Zhulin Tan, Diana C. Reeves, Jinhua J. Song, Paige E. Mahaney, Carl A. Busacca, Chris H. Senanayake, Hossein Razavi, Zhengxu S. Han, Yibo Xu, Bing-Shiou Yang, Daniel Kuzmich
Publikováno v:
Organic Process Research & Development. 18:904-911
A highly enantioselective enamide hydrogenation route to the title amine was developed. Highlights of the synthesis include an efficient two-step synthesis of a 2-sulfonyl 4-pyridyl ethyl ketone, a simple enamide synthesis by direct condensation of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c15d8bdc6de52c9a9d3c30e6c72243
https://doi.org/10.1021/op5001513
https://doi.org/10.1021/op5001513
Autor:
Sonia Rodriguez, Diana C. Reeves, Rogelio P. Frutos, Nitinchandra D. Patel, Tampone Thomas G, Chris H. Senanayake
Publikováno v:
Asian Journal of Organic Chemistry. 3:769-772
A practical, safe, and efficient synthesis of anti-inflammatory cytokine inhibitors was developed and implemented for a number of analogues. A key aspect of the process is an efficient, one-pot, tandem copper-catalyzed azidonation and Huisgen 1,3-dip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0615ffd7c5715a5efc9c0ff4882384db
https://doi.org/10.1002/ajoc.201400002
https://doi.org/10.1002/ajoc.201400002
Autor:
Dajun Chen, Bo Qu, Bruce Z. Lu, Carl A. Busacca, Keith R. Fandrick, Nicole Grět, Anjan Saha, Yaping Hong, Zhibin Li, Nizar Haddad, Diana C. Reeves, Shengli Ma, Jiang Ping Wu, Chris H. Senanayake, Magnus C. Eriksson, Heewon Lee, Nelu Grinberg, Maurice A. Marsini
Publikováno v:
Advanced Synthesis & Catalysis. 355:1455-1463
The modular nature of the BIPI ligands allows for systematic optimization of each ligand region. The development of ligands optimized for asymmetric hydrogenation of the challenging unfunctionalized olefin substrate class is described. The naphthyl p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30a9b36c4aa9ab5821b7b155f29eb34b
https://doi.org/10.1002/adsc.201201104
https://doi.org/10.1002/adsc.201201104
Autor:
Diana C. Reeves, Bruce Z. Lu, Jonathan T. Reeves, Zhengxu S. Han, Yibo Xu, Heewon Lee, Zhulin Tan, Chris H. Senanayake, Maurice A. Marsini
Publikováno v:
Advanced Synthesis & Catalysis. 355:47-52
A mild and general procedure for reduction of primary, secondary, and tertiary amides using catalytic triruthenium dodecacarbonyl and 1,1,3,3-tetramethyldisiloxane as reductant is described. The reaction is tolerant of numerous functional groups, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9866865489d3bdaa6647868445d454a6
https://doi.org/10.1002/adsc.201200835
https://doi.org/10.1002/adsc.201200835
Autor:
Chris H. Senanayake, Nelu Grinberg, Xingzhong Zeng, Nizar Haddad, Diana C. Reeves, Dhileepkumar Krishnamurthy, Shengli Ma, Carl A. Busacca, Bo Qu, Sonia Rodriguez, Kanwar Sidhu, Heewon Lee, Jon C. Lorenz
Publikováno v:
Tetrahedron Letters. 53:1982-1986
A novel trans-diastereoselective reductive amination of 4-substituted cyclohexanones is described using 9-BBN as reducing agent in the presence of FeCl3. The method permits efficient synthesis of structurally diverse 4-trans-alkoxycyclohexylamines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb48dab78adac17f8da008f7b7efb8d7
https://doi.org/10.1016/j.tetlet.2012.02.023
https://doi.org/10.1016/j.tetlet.2012.02.023
Autor:
Diana C. Reeves, Nina C. Gonnella, Shengli Ma, Guisheng Li, Jonathan T. Reeves, Yibo Xu, Zhulin Tan, Heewon Lee, Yongda Zhang, Zhengxu S. Han, Bruce Z. Lu, Chris H. Senanayake
Publikováno v:
Angewandte Chemie. 124:1429-1433
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82260a10088fdef6ce3ab4451ef51d11
https://doi.org/10.1002/ange.201107601
https://doi.org/10.1002/ange.201107601
Autor:
Nina C. Gonnella, Shengli Ma, Sonia Rodriguez, Nizar Haddad, Tobias Wunberg, Lars van der Veen, Diana C. Reeves, Chris H. Senanayake, Dhileepkumar Krishnamurthy, Heewon Lee, Nelu Grinberg, Bo Qu
Publikováno v:
Tetrahedron Letters. 52:3718-3722
An enantioselective hydrogenation of hydrazones derived from heterocyclic ketones was developed with up to 85% ee. The enantiomeric purity was enriched to >99% ee by crystallization from EtOAc in >80% yield. Optimization studies have revealed a notab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a03a85b814ff0d9cd44e4d04febcfa9
https://doi.org/10.1016/j.tetlet.2011.05.017
https://doi.org/10.1016/j.tetlet.2011.05.017
Autor:
Heewon Lee, Wenjun Tang, Diana C. Reeves, Dhileepkumar Krishnamurthy, Sonia Rodriguez, Bo Qu, Chris H. Senanayake, Nizar Haddad
Publikováno v:
Advanced Synthesis & Catalysis. 353:533-537
A novel class of C-2-substituted oxaphosphole-based monophosphines 1-4 has been synthesized. Palladium complexes derived from these ligands and their C-2-unsubstituted analogs provide general catalysts for amination reactions of challenging aryl and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcbf34f79a21c5d179c15c173e828477
https://doi.org/10.1002/adsc.201000878
https://doi.org/10.1002/adsc.201000878