Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Diana C Lozano"'
Autor:
Shandiz Tehrani, Lauren Davis, William O Cepurna, Tiffany E Choe, Diana C Lozano, Ashley Monfared, Lauren Cooper, Joshua Cheng, Elaine C Johnson, John C Morrison
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167364 (2016)
Glaucomatous axon injury occurs at the level of the optic nerve head (ONH) in response to uncontrolled intraocular pressure (IOP). The temporal response of ONH astrocytes (glial cells responsible for axonal support) to elevated IOP remains unknown. H
Externí odkaz:
https://doaj.org/article/4ca1ab736ffe460785f41277a95d4e77
Autor:
Shaohua Pi, Bingjie Wang, Min Gao, William Cepurna, Diana C. Lozano, John C. Morrison, Yali Jia
Publikováno v:
Investigative Opthalmology & Visual Science. 64:17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::089186597e4b4f6551684c75e8f0c136
https://doi.org/10.1167/iovs.64.4.17
https://doi.org/10.1167/iovs.64.4.17
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose We previously reported increased expression of cell proliferation and Jak-Stat pathway-related genes in chronic experimental glaucoma model optic nerve heads (ONH) with early, mild injury. Here, we confirm these observations by localizing, id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5867a2e38d7783b8548383a721a5bcd8
http://europepmc.org/articles/PMC6402265
http://europepmc.org/articles/PMC6402265
Autor:
William O. Cepurna, Diana C Lozano, Kate E. Keller, Jay Ian Phillips, Julie A. Saugstad, Devin M. Gattey, Hari Jayaram, Tiffany E. Choe, Elaine C. Johnson, John C. Morrison
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose MicroRNAs (miRNAs) are small, endogenous noncoding RNAs that have been detected in human aqueous humor (AH). Prior studies have pooled samples to obtain sufficient quantities for analysis or used next-generation sequencing. Here, we used PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd47a9d2d645ce4f3b95e3a94e784a66
http://europepmc.org/articles/PMC5460954
http://europepmc.org/articles/PMC5460954
Publikováno v:
Glaucoma ISBN: 9781493974061
MicroRNAs are small, endogenous noncoding RNAs that modulate post-transcriptional gene expression. Recent evidence suggests that they may have a potential role in the regulation of the complex biological responses that develop in response to elevated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e276548ea5619037ee9e97e5e05addb
https://doi.org/10.1007/978-1-4939-7407-8_19
https://doi.org/10.1007/978-1-4939-7407-8_19
Publikováno v:
Glaucoma ISBN: 9781493974061
Understanding the cellular pathways activated by elevated intraocular pressure (IOP) is crucial for the development of more effective glaucoma treatments. Microarray studies have previously been used to identify several key gene expression changes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0865932696602cd058444fbd4765df71
https://doi.org/10.1007/978-1-4939-7407-8_20
https://doi.org/10.1007/978-1-4939-7407-8_20
Autor:
Diana C Lozano, Xiaoyun Jiang, Ruikang K. Wang, Shaojie Men, Elaine C. Johnson, John C. Morrison, William O. Cepurna
Publikováno v:
Microvascular research. 115
Purpose To compare the effect of elevated intraocular pressure (IOP) on retinal capillary filling in elderly vs adult rats using optical coherence tomography angiography (OCTA). Methods The IOP of elderly (24-month-old, N = 12) and adult (6–8 month
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61d76c7a2b2d0ed58b6a701452ba432
https://pubmed.ncbi.nlm.nih.gov/28782513
https://pubmed.ncbi.nlm.nih.gov/28782513
Autor:
Shandiz Tehrani, Diana C Lozano, William O. Cepurna, Elaine C. Johnson, Lauren Davis, R. Katherine Delf, John C. Morrison, Tiffany E. Choe
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Optic nerve head (ONH) astrocytes provide support for axons, but exhibit structural and functional changes (termed reactivity) in a number of glaucoma models. The purpose of this study was to determine if ONH astrocyte structural reactivity i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f13a520fb9233429a07ffd0db45a52
https://doi.org/10.1167/iovs.18-25447
https://doi.org/10.1167/iovs.18-25447
Autor:
Diana C Lozano, Lauren Davis, Tiffany E. Choe, Elaine C. Johnson, William O. Cepurna, Shandiz Tehrani, Ashley Monfared, Lauren Cooper, John C. Morrison, Joshua Cheng
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167364 (2016)
PLoS ONE
PLoS ONE
Glaucomatous axon injury occurs at the level of the optic nerve head (ONH) in response to uncontrolled intraocular pressure (IOP). The temporal response of ONH astrocytes (glial cells responsible for axonal support) to elevated IOP remains unknown. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac79b5e175c7c5b7cc5d984d5162cc3
http://europepmc.org/articles/PMC5125687?pdf=render
http://europepmc.org/articles/PMC5125687?pdf=render
Publikováno v:
Chronobiology international. 32(4)
Ocular hypertension is a risk factor for developing glaucoma, which consists of a group of optic neuropathies characterized by progressive degeneration of retinal ganglion cells and subsequent irreversible vision loss. Our understanding of how intrao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e8de7a77d799b784830f941cfbc40c
https://pubmed.ncbi.nlm.nih.gov/25799136
https://pubmed.ncbi.nlm.nih.gov/25799136