Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Diana Besser"'
Publikováno v:
The Journal of Peptide Research. 56:337-345
The cyclization kinetics of five backbone-cyclic tetrapeptides was investigated both experimentally and computationally. The aim was to both accurately measure the cyclization rates in solution and develop a method that efficiently estimates the rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8158f44e06bcf5aedb7af38e0807e8c4
https://doi.org/10.1034/j.1399-3011.2000.00735.x
https://doi.org/10.1034/j.1399-3011.2000.00735.x
Autor:
Siegmund Reissmann, Oded Arad, Torsten Steinmetzer, Lydia Seyfarth, Georg Greiner, Peter Kleinwächter, Diana Besser, Bettina Müller
Publikováno v:
Journal für praktische Chemie. 342:537-545
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::035e53aa43c39202eff70d402ecdc9b6
https://doi.org/10.1002/1521-3897(200006)342:6<537::aid-prac537>3.0.co
https://doi.org/10.1002/1521-3897(200006)342:6<537::aid-prac537>3.0.co
Publikováno v:
Journal of Peptide Science. 6:130-138
Backbone cyclization has become an important method for generating or stabilizing the bioactive conformation of peptides without affecting the amino acid side-chains. Up to now, backbone cyclic peptides were mostly synthesized with bridges between N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a393fc53113b80d3496f9cec2d153f04
https://doi.org/10.1002/(sici)1099-1387(200003)6:3<130::aid-psc237>3.0.co
https://doi.org/10.1002/(sici)1099-1387(200003)6:3<130::aid-psc237>3.0.co
Publikováno v:
The Journal of Peptide Research. 54:383-393
To improve the assembly of backbone cyclic peptides, N-functionalized dipeptide building units were synthesized. The corresponding N-aminoalkyl or N-carboxyalkyl amino acids were formed by alkylation or reductive alkylation of amino acid benzyl or te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c763e3021ac288acb60cce3995aac06
https://doi.org/10.1034/j.1399-3011.1999.00116.x
https://doi.org/10.1034/j.1399-3011.1999.00116.x
Publikováno v:
Letters in Peptide Science. 5:299-303
The use of N-carboxymethyl amino acids in the assembly of peptides with backbone cyclization can lead to diketopiperazine formation by intramolecular aminolysis which occurs despite the tert-butyl protection of the carboxy group. This undesired side
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab7c0fbee26264199ee24aecf2265517
https://doi.org/10.1007/bf02443547
https://doi.org/10.1007/bf02443547