Effect of Local Administration of Meglumine Antimoniate and Polyhexamethylene Biguanide Alone or in Combination with a Toll-like Receptor 4 Agonist for the Treatment of Papular Dermatitis due to Leishmania infantum in Dogs

Autor: Icíar Martínez-Flórez, Maria Jose Guerrero, Annabel Dalmau, Maria Cabré, Maria Magdalena Alcover, Diana Berenguer, Liam Good, Roser Fisa, Cristina Riera, Laura Ordeix, Laia Solano-Gallego

Publikováno v: Pathogens, Vol 12, Iss 6, p 821 (2023)

Papular dermatitis is a cutaneous manifestation of canine Leishmania infantum infection associated with mild disease. Although it is a typical presentation, nowadays, there is still no established treatment. This study evaluated the safety and clinic

Externí odkaz: https://doaj.org/article/08a6639f66eb4e5081642cc7f45bf7d8

Topical Amphotericin B Semisolid Dosage Form for Cutaneous Leishmaniasis: Physicochemical Characterization, Ex Vivo Skin Permeation and Biological Activity

Autor: Diana Berenguer, Maria Magdalena Alcover, Marcella Sessa, Lyda Halbaut, Carme Guillén, Antoni Boix-Montañés, Roser Fisa, Ana Cristina Calpena-Campmany, Cristina Riera, Lilian Sosa

Publikováno v: Pharmaceutics, Vol 12, Iss 2, p 149 (2020)

Amphotericin B (AmB) is a potent antifungal successfully used intravenously to treat visceral leishmaniasis but depending on the Leishmania infecting species, it is not always recommended against cutaneous leishmaniasis (CL). To address the need for

Externí odkaz: https://doaj.org/article/07458a352c3d42a9949dd10bf0f9a637

Polyamidoamine Nanoparticles for the Oral Administration of Antimalarial Drugs

Autor: Elisabet Martí Coma-Cros, Arnau Biosca, Joana Marques, Laura Carol, Patricia Urbán, Diana Berenguer, Maria Cristina Riera, Michael Delves, Robert E. Sinden, Juan José Valle-Delgado, Lefteris Spanos, Inga Siden-Kiamos, Paula Pérez, Krijn Paaijmans, Matthias Rottmann, Amedea Manfredi, Paolo Ferruti, Elisabetta Ranucci, Xavier Fernàndez-Busquets

Publikováno v: Pharmaceutics, Vol 10, Iss 4, p 225 (2018)

Current strategies for the mass administration of antimalarial drugs demand oral formulations to target the asexual Plasmodium stages in the peripheral bloodstream, whereas recommendations for future interventions stress the importance of also target

Externí odkaz: https://doaj.org/article/b295ff5e39894a82946f782bfd2b62ec

Leishmania infantum asymptomatic infection in inflammatory bowel disease patients under anti-TNF therapy

Autor: Diana Berenguer, Natalia Borruel, Elena Sulleiro, Adrián Sánchez-Montalvá, Zaira Moure, Claudia Herrera-de Guise, Roser Fisa, Verónica Rodríguez, M. Carmen Guillén, Fernando Salvador, Cristina Riera, Israel Molina, M. Magdalena Alcover

Publikováno v: Heliyon, Vol 6, Iss 5, Pp e03940-(2020)
Dipòsit Digital de la UB
Universidad de Barcelona
Heliyon

Background In recent years anti-TNF therapy has been associated with leishmaniasis in immunocompromised patients from endemic areas. Nevertheless, data on asymptomatic Leishmania infection in such patients is scarce. The aim of this study was to dete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea57d4e426b89ba7d60facb9e2ec4c69
http://www.sciencedirect.com/science/article/pii/S2405844020307854

Development and Characterization of a Semi-Solid Dosage Form of Meglumine Antimoniate for Topical Treatment of Cutaneous Leishmaniasis

Autor: Roser Fisa, Carme Guillén, Diana Berenguer, Ana C. Calpena-Campmany, Magdalena Alcover, Lyda Halbaut, Lilian Sosa, Marcella Sessa, Cristina Riera

Publikováno v: Pharmaceutics, Vol 11, Iss 11, p 613 (2019)
Pharmaceutics
Volume 11
Issue 11
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Cutaneous leishmaniasis (CL) is treated with painful intralesional injections of meglumine antimoniate (MA). With the aim of developing an alternative topical treatment for CL, a gel-based formulation with 30% MA was prepared and its physicochemical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1d978cb324147135ff3ea5f652b80b
http://hdl.handle.net/2445/146042