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pro vyhledávání: '"Diana Alnemri"'
Autor:
Corey Rogers, Teresa Fernandes-Alnemri, Lindsey Mayes, Diana Alnemri, Gino Cingolani, Emad S. Alnemri
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
DFNA5 is related to the caspase-dependent pyroptosis inducer gasdermin D. Here the authors find that DFNA5 is cleaved by caspase 3 and show this cleavage skews cells away from apoptosis into secondary necrosis, a form of cell death characterized by m
Externí odkaz:
https://doaj.org/article/ede72842f24b4015bf734b0a8c6dee76
Autor:
Emad S. Alnemri, Gino Cingolani, Corey Rogers, Lindsey Mayes, Diana Alnemri, Teresa Fernandes-Alnemri
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Apoptosis is a genetically regulated cell suicide programme mediated by activation of the effector caspases 3, 6 and 7. If apoptotic cells are not scavenged, they progress to a lytic and inflammatory phase called secondary necrosis. The mechanism by