Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Diana Abbott"'
Autor:
Amanda C. Winters, Mohd Minhajuddin, Brett M. Stevens, Ajay Major, Grace Bosma, Diana Abbott, Nicholas Miltgen, Ji Yuan, Amy L. Treece, Bradford J. Siegele, Mark D. Ewalt, Jonathan A. Gutman, Craig T. Jordan, Daniel A. Pollyea
Publikováno v:
Haematologica, Vol 109, Iss 6 (2023)
Venetoclax with azacitidine (ven/aza) is a lower-intensity therapeutic regimen that has been shown to improve outcomes in elderly patients with acute myeloid leukemia (AML). Measurable residual disease (MRD) using flow cytometry is a valuable tool fo
Externí odkaz:
https://doaj.org/article/dd1f3941b21d43f7a99618a3961ccd30
Autor:
Jonathan A. Gutman, Amanda Winters, Andrew Kent, Maria Amaya, Christine McMahon, Clayton Smith, Craig T. Jordan, Brett Stevens, Mohammad Minhajuddin, Shanshan Pei, Jeffrey Schowinsky, Jennifer Tobin, Kelly O’Brien, Angela Falco, Elizabeth Taylor, Constance Brecl, Katie Zhou, Phuong Ho, Connor Sohalski, Jessica Dell-Martin, Olivia Ondracek, Diana Abbott, Daniel A. Pollyea
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
Venetoclax+azacitidine is the standard of care for newly-diagnosed patients with acute myeloid leukemia (AML) for whom intensive chemotherapy is inappropriate. Efforts to optimize this regimen are necessary. We designed a clinical trial to investigat
Externí odkaz:
https://doaj.org/article/4bed77ea2bb644d486a34c85f8f12b19
Autor:
Courtney Samuels, Diana Abbott, Sierra Niemiec, Jennifer Tobin, Angela Falco, Keri Halsema, Manali Kamdar
Publikováno v:
Cancer Reports, Vol 5, Iss 5, Pp n/a-n/a (2022)
Abstract Background The time‐limited combination of venetoclax and obinutuzumab (VenG) was established by the German CLL Study Group in the CLL14 trial for the upfront management of newly diagnosed chronic lymphocytic leukemia (CLL), showing a supe
Externí odkaz:
https://doaj.org/article/33e88e0fd26a4cd3b7f3f4a497f872e1
Autor:
Diana Abbott, Schuyler O'Brien, James M. Farnham, Erin L. Young, Jeffrey Yap, Kevin Jones, Stephen L. Lessnick, R. Lor Randall, Joshua D. Schiffman, Lisa A. Cannon‐Albright
Publikováno v:
Cancer Medicine, Vol 8, Iss 18, Pp 7924-7930 (2019)
Abstract Background There are few reports of the association of other cancers with Ewing sarcoma in patients and their relatives. We use a resource combining statewide genealogy and cancer reporting to provide unbiased risks. Methods Using a combined
Externí odkaz:
https://doaj.org/article/ced2ef5e24a74b49a07f70c3460a81e2
Autor:
Amanda C. Winters, Jonathan A. Gutman, Enkhtsetseg Purev, Molly Nakic, Jennifer Tobin, Stephanie Chase, Jeff Kaiser, Lindsey Lyle, Chelsey Boggs, Keri Halsema, Jeffrey T. Schowinsky, Julie Rosser, Mark D. Ewalt, Bradford Siegele, Vishal Rana, Steven Schuster, Diana Abbott, Brett M. Stevens, Craig T. Jordan, Clayton Smith, Daniel A. Pollyea
Publikováno v:
Blood Advances, Vol 3, Iss 20, Pp 2911-2919 (2019)
Abstract: Venetoclax is approved for older untreated acute myeloid leukemia (AML) patients. Venetoclax was available prior to approval off-label. We assessed our single-institution off-label experience with venetoclax/azacitidine, comparing outcomes
Externí odkaz:
https://doaj.org/article/1934278e1f804e4f9fde48ee8377753e
Autor:
Sarah Hummel, Wendy Kohlmann, Thomas M. Kollmeyer, Robert Jenkins, Joshua Sonnen, Cheryl A. Palmer, Howard Colman, Diana Abbott, Lisa Cannon-Albright, Adam L. Cohen
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-6 (2019)
Abstract Background IDH1/2 mutated glioma has been associated with a germline risk variant, the rs55705857 G allele. The Utah Population Database (UPDB), a computerized genealogy of people in Utah, is a unique resource to evaluate cancer risk in rela
Externí odkaz:
https://doaj.org/article/ab2501c8329a4d46824e64063692d3de
Autor:
Whitney A. Sumner, William A. Stokes, Ayman Oweida, Kiersten L. Berggren, Jessica D. McDermott, David Raben, Diana Abbott, Bernard Jones, Gregory Gan, Sana D. Karam
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-9 (2017)
Abstract Background Squamous cell carcinoma of the head and neck (HNSCC) represents an array of disease processes with a generally unfavorable prognosis. Inflammation plays an important role in tumor development and response to therapy. We performed
Externí odkaz:
https://doaj.org/article/bb1d6fbae4c343e6ba4d0e81a39e10bf
Autor:
Craig T. Jordan, Clayton A. Smith, Michael R. Savona, Haley E. Ramsey, Jonathan A. Gutman, Angelo D'Alessandro, Travis Nemkov, John M. Ashton, Jason R. Myers, Andrew Hammes, Diana Abbott, Jeffrey Schowinsky, Jessica Ponder, Nabilah Khan, Biniam Adane, Courtney L. Jones, Anna Krug, Haobin Ye, Amanda Winters, Anagha Inguva, Maria L. Amaya, James C. Costello, Jihye Kim, Ryan M. Sheridan, Austin E. Gillen, Kent A. Riemondy, Rui Fu, Mohammad Minhajuddin, Brett M. Stevens, Annika Gustafson, Daniel A. Pollyea, Shanshan Pei
Venetoclax-based therapy can induce responses in approximately 70% of older previously untreated patients with acute myeloid leukemia (AML). However, up-front resistance as well as relapse following initial response demonstrates the need for a deeper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::459448356d6d6a3954afc463053a8909
https://doi.org/10.1158/2159-8290.c.6547874.v1
https://doi.org/10.1158/2159-8290.c.6547874.v1
Autor:
Craig T. Jordan, Clayton A. Smith, Michael R. Savona, Haley E. Ramsey, Jonathan A. Gutman, Angelo D'Alessandro, Travis Nemkov, John M. Ashton, Jason R. Myers, Andrew Hammes, Diana Abbott, Jeffrey Schowinsky, Jessica Ponder, Nabilah Khan, Biniam Adane, Courtney L. Jones, Anna Krug, Haobin Ye, Amanda Winters, Anagha Inguva, Maria L. Amaya, James C. Costello, Jihye Kim, Ryan M. Sheridan, Austin E. Gillen, Kent A. Riemondy, Rui Fu, Mohammad Minhajuddin, Brett M. Stevens, Annika Gustafson, Daniel A. Pollyea, Shanshan Pei
Supplementary Figures S1-S5 supporting Main Figures 1-5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a46cf40c0c33f9430520efc19df38f
https://doi.org/10.1158/2159-8290.22535510
https://doi.org/10.1158/2159-8290.22535510
Autor:
Craig T. Jordan, Clayton A. Smith, Michael R. Savona, Haley E. Ramsey, Jonathan A. Gutman, Angelo D'Alessandro, Travis Nemkov, John M. Ashton, Jason R. Myers, Andrew Hammes, Diana Abbott, Jeffrey Schowinsky, Jessica Ponder, Nabilah Khan, Biniam Adane, Courtney L. Jones, Anna Krug, Haobin Ye, Amanda Winters, Anagha Inguva, Maria L. Amaya, James C. Costello, Jihye Kim, Ryan M. Sheridan, Austin E. Gillen, Kent A. Riemondy, Rui Fu, Mohammad Minhajuddin, Brett M. Stevens, Annika Gustafson, Daniel A. Pollyea, Shanshan Pei
Supplementary Tables S1-S6 describing patient characteristics, gene lists, LSC signatures, and reagents.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6aa26137a69b33270a49fa503428b1
https://doi.org/10.1158/2159-8290.22535507.v1
https://doi.org/10.1158/2159-8290.22535507.v1