Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Diana A. T. Nijholt"'
Autor:
Annemieke J.M. Rozemuller, Diana A. T. Nijholt, John C. van Swieten, André G. Uitterlinden, Jeroen van Rooij, Shami Melhem, Tsz Hang Wong, Lieke H.H. Meeter, Joyce G. van Meurs
Publikováno v:
Neurobiology of Aging, 74, 225-233. Elsevier B.V.
Neurobiology of Aging, 74, 225-233. Elsevier Inc.
van Rooij, J G J, Meeter, L H H, Melhem, S, Nijholt, D A T, Wong, T H, Rozemuller, A, Uitterlinden, A G, van Meurs, J G, van Swieten, J C & Netherlands Brain Bank 2019, ' Hippocampal transcriptome profiling combined with protein-protein interaction analysis elucidates Alzheimer's disease pathways and genes ', Neurobiology of Aging, vol. 74, pp. 225-233 . https://doi.org/10.1016/j.neurobiolaging.2018.10.023
Neurobiology of Aging, 74, 225-233. Elsevier Inc.
van Rooij, J G J, Meeter, L H H, Melhem, S, Nijholt, D A T, Wong, T H, Rozemuller, A, Uitterlinden, A G, van Meurs, J G, van Swieten, J C & Netherlands Brain Bank 2019, ' Hippocampal transcriptome profiling combined with protein-protein interaction analysis elucidates Alzheimer's disease pathways and genes ', Neurobiology of Aging, vol. 74, pp. 225-233 . https://doi.org/10.1016/j.neurobiolaging.2018.10.023
Knowledge about the molecular mechanisms driving Alzheimer's disease (AD) is still limited. To learn more about AD biology, we performed whole transcriptome sequencing on the hippocampus of 20 AD cases and 10 age- and sex-matched cognitively healthy
Autor:
Yolande A.L. Pijnenburg, Corey T. McMillan, Lieke H.H. Meeter, Harro Seelaar, Theo M. Luider, Murray Grossman, Caroline Graff, Linn Öijerstedt, Diana A. T. Nijholt, Roberta Ghidoni, Raquel Sánchez-Valle, Giuliano Binetti, Robert Laforce, Christoph Stingl, Marcel P. Stoop, John C. van Swieten, Luisa Benussi, Jeroen van Rooij, Emma L. van der Ende
Publikováno v:
Annals of Clinical and Translational Neurology, 6(4), 698-707. John Wiley and Sons Ltd
Annals of Clinical and Translational Neurology
van der Ende, E L, Meeter, L H, Stingl, C, van Rooij, J G J, Stoop, M P, Nijholt, D A T, Sanchez-Valle, R, Graff, C, Öijerstedt, L, Grossman, M, McMillan, C, Pijnenburg, Y A L, Laforce, R, Binetti, G, Benussi, L, Ghidoni, R, Luider, T M, Seelaar, H & van Swieten, J C 2019, ' Novel CSF biomarkers in genetic frontotemporal dementia identified by proteomics ', Annals of Clinical and Translational Neurology, vol. 6, no. 4, pp. 698-707 . https://doi.org/10.1002/acn3.745
Annals of Clinical and Translational Neurology, 6(4), 698-707. John Wiley & Sons Inc.
Annals of Clinical and Translational Neurology
van der Ende, E L, Meeter, L H, Stingl, C, van Rooij, J G J, Stoop, M P, Nijholt, D A T, Sanchez-Valle, R, Graff, C, Öijerstedt, L, Grossman, M, McMillan, C, Pijnenburg, Y A L, Laforce, R, Binetti, G, Benussi, L, Ghidoni, R, Luider, T M, Seelaar, H & van Swieten, J C 2019, ' Novel CSF biomarkers in genetic frontotemporal dementia identified by proteomics ', Annals of Clinical and Translational Neurology, vol. 6, no. 4, pp. 698-707 . https://doi.org/10.1002/acn3.745
Annals of Clinical and Translational Neurology, 6(4), 698-707. John Wiley & Sons Inc.
Objective: To identify novel CSF biomarkers in GRN-associated frontotemporal dementia (FTD) by proteomics using mass spectrometry (MS). Methods: Unbiased MS was applied to CSF samples from 19 presymptomatic and 9 symptomatic GRN mutation carriers and
Autor:
Shami Melhem, Jeroen van Rooij, John C. van Swieten, Annemieke J.M. Rozemuller, Diana A. T. Nijholt, Joyce B. J. van Meurs, Lieke H.H. Meeter, André G. Uitterlinden
Publikováno v:
Alzheimer's & Dementia. 12
Autor:
Ping-Pin Zheng, Diana A. T. Nijholt, Peter J. Koudstaal, Peter A. E. Sillevis Smitt, Linda IJsselstijn, Johan M. Kros, Theo M. Luider, Marcel van der Weiden
Publikováno v:
Journal of Alzheimers Disease, 46(1), 227-238. IOS Press BV
Increased levels of pregnancy zone protein (PZP) were found in the serum of persons who later developed Alzheimer's disease (AD) in comparison to controls who remained dementia free. We suggested that this increase is due to brain derived PZP enterin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6469afd5f45c3abad553332fe3dbaf5d
https://pure.eur.nl/en/publications/4e52e1b9-50fc-4476-b817-d86d207d4197
https://pure.eur.nl/en/publications/4e52e1b9-50fc-4476-b817-d86d207d4197
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1243
Laser capture microdissection (LCM) is used to isolate minute amounts of tissue for subsequent proteomics analysis. An advantage of this technique is that a specific subset of cells or tissue structures can be isolated and enriched from surrounding m
Publikováno v:
Methods in Molecular Biology ISBN: 9781493918713
Laser capture microdissection (LCM) is used to isolate minute amounts of tissue for subsequent proteomics analysis. An advantage of this technique is that a specific subset of cells or tissue structures can be isolated and enriched from surrounding m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15cc34501542ef02f9ee2afc9fb316bf
https://doi.org/10.1007/978-1-4939-1872-0_9
https://doi.org/10.1007/978-1-4939-1872-0_9
Autor:
Peter A.E. Sillevis-Smitt, Peter J. Koudstaal, Johan M. Kros, Theo M. Luider, Mohammad Arfan Ikram, Diana A. T. Nijholt, Marcel van der Weiden
Publikováno v:
Alzheimer's & Dementia. 9
Autor:
Diana A T, Nijholt, Elise S, van Haastert, Annemieke J M, Rozemuller, Wiep, Scheper, Jeroen J M, Hoozemans
Publikováno v:
The Journal of pathology. 226(5)
The unfolded protein response (UPR) is a stress response activated upon disturbed homeostasis in the endoplasmic reticulum (ER). Previously, we reported that the activation of the UPR closely correlates with the presence of phosphorylated tau (p-tau)