Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Diana, Reinhardt"'
Autor:
Lisa-Maria Winter, Diana Reinhardt, Ariane Schatter, Vivien Tissen, Heike Wiora, Daniel Gerlach, Ulrike Tontsch-Grunt, Florian Colbatzky, Birgit Stierstorfer, Seong-Wook Yun
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract GDF15 has recently emerged as a key driver of the development of various disease conditions including cancer cachexia. Not only the tumor itself but also adverse effects of chemotherapy have been reported to contribute to increased GDF15. Al
Externí odkaz:
https://doaj.org/article/824669cb47604d63b4686cf0ba92e957
Autor:
Colm E, Nestor, Raffaele, Ottaviano, Diana, Reinhardt, Hazel A, Cruickshanks, Heidi K, Mjoseng, Rhoanne C, McPherson, Antonio, Lentini, John P, Thomson, Donncha S, Dunican, Sari, Pennings, Stephen M, Anderton, Mikael, Benson, Richard R, Meehan
Publikováno v:
Genome Biology
Background The DNA methylation profiles of mammalian cell lines differ from those of the primary tissues from which they were derived, exhibiting increasing divergence from the in vivo methylation profile with extended time in culture. Few studies ha
Autor:
Erin A. Scheessele, Diana Reinhardt, Jonathan N. Berg, Douglas A. Marchuk, Ashley J. Duits, Cornelius J.J. Westermann, Carol J. Gallione
Publikováno v:
Human Genetics. 107:40-44
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant bleeding disorder characterized by localized angiodysplasia. Mutations in either of two genes, endoglin or ALK-1, can cause HHT. Both genes encode putative receptors for the transfo
Autor:
Neil A. Youngson, James P. Reddington, Colm E. Nestor, Judith Reichmann, Heidi K. Mjoseng, Emma Whitelaw, Wendy A. Bickmore, Masako Suzuki, Donncha S. Dunican, James G. D. Prendergast, Ian R. Adams, John M. Greally, Diana Reinhardt, Sara M Perricone, Richard R. Meehan, Bernard Ramsahoye
Publikováno v:
Reddington, J P, Perricone, S M, Nestor, C E, Reichmann, J, Youngson, N A, Suzuki, M, Reinhardt, D, Dunican, D S, Prendergast, J G, Mjoseng, H, Ramsahoye, B H, Whitelaw, E, Greally, J M, Adams, I R, Bickmore, W A & Meehan, R 2013, ' Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes ', Genome Biology, vol. 14, no. 3, R25 . https://doi.org/10.1186/gb-2013-14-3-r25
Genome Biology
Genome Biology
BackgroundDNA methylation and the Polycomb repression system are epigenetic mechanisms that play important roles in maintaining transcriptional repression. Recent evidence suggests that DNA methylation can attenuate the binding of Polycomb protein co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4fd39434cbb194f4a8730076f47b44
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-100010
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-100010
Autor:
Federico Bolognani, Rémi Terranova, Jamie A. Hackett, Harri Lempiäinen, Jonathan G. Moggs, Dirk Schübeler, Colm E. Nestor, John P. Thomson, Arne Müller, Diana Reinhardt, Edward J. Oakeley, Richard R. Meehan
Publikováno v:
Thomson, J P, Lempiäinen, H, Hackett, J A, Nestor, C E, Müller, A, Bolognani, F, Oakeley, E J, Schübeler, D, Terranova, R, Reinhardt, D, Moggs, J G & Meehan, R 2012, ' Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome ', Genome Biology, vol. 13, no. 10, R93 . https://doi.org/10.1186/gb-2012-13-10-r93
Genome Biology
Genome Biology
BACKGROUND: Induction and promotion of liver cancer by exposure to non-genotoxic carcinogens coincides with epigenetic perturbations, including specific changes in DNA methylation. Here we investigate the genome-wide dynamics of 5-hydroxymethylcytosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a35494b80aa8c8fbcce4bcafa9d4ee7
https://www.pure.ed.ac.uk/ws/files/7957473/Non_genotoxic_carcinogen_exposure_induces_defined_changes_in_the_5_hydroxymethylome.pdf
https://www.pure.ed.ac.uk/ws/files/7957473/Non_genotoxic_carcinogen_exposure_induces_defined_changes_in_the_5_hydroxymethylome.pdf
Autor:
Duncan Sproul, Richard R. Meehan, Raffaele Ottaviano, David J. Harrison, Donncha S. Dunican, Diana Reinhardt, Colm E. Nestor, Elad Katz, James P. Reddington, J Michael Dixon
Publikováno v:
Nestor, C E, Ottaviano, R, Reddington, J, Sproul, D, Reinhardt, D, Dunican, D, Katz, E, Dixon, J M, Harrison, D J & Meehan, R R 2012, ' Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes ', Genome Research, vol. 22, no. 3, pp. 467-477 . https://doi.org/10.1101/gr.126417.111
The discovery of substantial amounts of 5-hydroxymethylcytosine (5hmC), formed by the oxidation of 5-methylcytosine (5mC), in various mouse tissues and human embryonic stem (ES) cells has necessitated a reevaluation of our knowledge of 5mC/5hmC patte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380c096bc4e70e41530c78c27d238d4f
https://hdl.handle.net/20.500.11820/cd2e3474-7a3b-43d7-8b64-d2e257571c8f
https://hdl.handle.net/20.500.11820/cd2e3474-7a3b-43d7-8b64-d2e257571c8f
Autor:
Jonathan Berg, Carol J. Gallione, Douglas A. Marchuk, Diana Reinhardt, Alan E. Guttmacher, Susan Holloway, Mary Porteous, Andreas Lux, T Umasunthar, Wendy McKinnon
Background: Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant vascular dysplasia characterised by mucocutaneous telangiectasis, epistaxis, gastrointestinal haemorrhage, and arteriovenous malformations in the lung and brain. Causat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4b945f9609426df83ef4cd817d7cb2
https://europepmc.org/articles/PMC1735540/
https://europepmc.org/articles/PMC1735540/