Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Diana, Le Duc"'
Autor:
André Nguyen Dietzsch, Hadi Al-Hasani, Joachim Altschmied, Katharina Bottermann, Jana Brendler, Judith Haendeler, Susanne Horn, Isabell Kaczmarek, Antje Körner, Kerstin Krause, Kathrin Landgraf, Diana Le Duc, Laura Lehmann, Stefan Lehr, Stephanie Pick, Albert Ricken, Rene Schnorr, Angela Schulz, Martina Strnadová, Akhil Velluva, Heba Zabri, Torsten Schöneberg, Doreen Thor, Simone Prömel
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Obesity is one of the diseases with severe health consequences and rapidly increasing worldwide prevalence. Understanding the complex network of food intake and energy balance regulation is an essential prerequisite for pharmacological inter
Externí odkaz:
https://doaj.org/article/b3c4ff1f595a49f8b5c14bc0d3761921
Autor:
Marek B. Körner, Akhil Velluva, Linnaeus Bundalian, Maximilian Radtke, Chen-Ching Lin, Pia Zacher, Tobias Bartolomaeus, Anna S. Kirstein, Achmed Mrestani, Nicole Scholz, Konrad Platzer, Anne-Christin Teichmann, Julia Hentschel, Tobias Langenhan, Johannes R. Lemke, Antje Garten, Rami Abou Jamra, Diana Le Duc
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The 15q13.3 microdeletion has pleiotropic effects ranging from apparently healthy to severely affected individuals. The underlying basis of the variable phenotype remains elusive. We analyzed gene expression using blood from three individual
Externí odkaz:
https://doaj.org/article/f0c825a9e8ef41399622f3cfb955f5f9
Autor:
Akhil Velluva, Maximillian Radtke, Susanne Horn, Bernt Popp, Konrad Platzer, Erind Gjermeni, Chen-Ching Lin, Johannes R. Lemke, Antje Garten, Torsten Schöneberg, Matthias Blüher, Rami Abou Jamra, Diana Le Duc
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background RNA-seq emerges as a valuable method for clinical genetics. The transcriptome is “dynamic” and tissue-specific, but typically the probed tissues to analyze (TA) are different from the tissue of interest (TI) based on pathophys
Externí odkaz:
https://doaj.org/article/ac3037e353d248199606be6e0d9be1b9
Autor:
Davor Lessel, Daniela M. Zeitler, Margot R. F. Reijnders, Andriy Kazantsev, Fatemeh Hassani Nia, Alexander Bartholomäus, Victoria Martens, Astrid Bruckmann, Veronika Graus, Allyn McConkie-Rosell, Marie McDonald, Bernarda Lozic, Ee-Shien Tan, Erica Gerkes, Jessika Johannsen, Jonas Denecke, Aida Telegrafi, Evelien Zonneveld-Huijssoon, Henny H. Lemmink, Breana W. M. Cham, Tanja Kovacevic, Linda Ramsdell, Kimberly Foss, Diana Le Duc, Diana Mitter, Steffen Syrbe, Andreas Merkenschlager, Margje Sinnema, Bianca Panis, Joanna Lazier, Matthew Osmond, Taila Hartley, Jeremie Mortreux, Tiffany Busa, Chantal Missirian, Pankaj Prasun, Sabine Lüttgen, Ilaria Mannucci, Ivana Lessel, Claudia Schob, Stefan Kindler, John Pappas, Rachel Rabin, Marjolein Willemsen, Thatjana Gardeitchik, Katharina Löhner, Patrick Rump, Kerith-Rae Dias, Carey-Anne Evans, Peter Ian Andrews, Tony Roscioli, Han G. Brunner, Chieko Chijiwa, M. E. Suzanne Lewis, Rami Abou Jamra, David A. Dyment, Kym M. Boycott, Alexander P. A. Stegmann, Christian Kubisch, Ene-Choo Tan, Ghayda M. Mirzaa, Kirsty McWalter, Tjitske Kleefstra, Rolph Pfundt, Zoya Ignatova, Gunter Meister, Hans-Jürgen Kreienkamp
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
AGO2 binds to miRNAs to repress expression of cognate target mRNAs. Here the authors report that heterozygous AGO2 mutations result in defects in neurological development and impair RNA interference.
Externí odkaz:
https://doaj.org/article/d67d1cc583c34e7f9e0a8f4ce72015a2
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 3, Pp 485-490 (2019)
Alcohol, a widely abused drug, has deleterious effects on the immature nervous system. This study investigates the effect of chronic in vitro ethanol exposure on the metabolism of immature rat cerebellar granular cells (CGCs) and on their response to
Externí odkaz:
https://doaj.org/article/aad0ec1f1d62402295a9193347472137
Publikováno v:
BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background The common loon (Gavia immer) is one of five species that comprise the avian order Gaviiformes. Loons are specialized divers, reaching depths up to 60 m while staying submerged for intervals up to three minutes. In this study we u
Externí odkaz:
https://doaj.org/article/6a42763792d54440bee90fd5e15f5435
Autor:
Erind Gjermeni, Anna S. Kirstein, Florentien Kolbig, Michael Kirchhof, Linnaeus Bundalian, Julius L. Katzmann, Ulrich Laufs, Matthias Blüher, Antje Garten, Diana Le Duc
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1426 (2021)
Obesity represents a major public health problem with a prevalence increasing at an alarming rate worldwide. Continuous intensive efforts to elucidate the complex pathophysiology and improve clinical management have led to a better understanding of b
Externí odkaz:
https://doaj.org/article/98a93bc88d7a4593b79db948734a7940
Autor:
Lei Xu, Uwe Wolfrum, Yuri Ushkaryov, Martin Stacey, Kathleen Singer, Helgi Schiöth, Torsten Schöneberg, Simone Prömel, Xianhua Piao, Kelly Monk, David C. Martinelli, Hsi-Hsien Lin, Diana Le Duc, Tobias Langenhan, Arunkumar Krishnan, Barbara Knapp, Christiane Kirchhoff, Henrike Heyne, Breanne Harty, Jörg Hamann, Caroline Formstone, Heike Cappallo-Obermann, Tom I. Bonner, Gabriela Aust, Demet Arac-Ozkan
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Adhesion GPCRs are structurally identified on the basis of a large extracellular region, similar to the Class B GPCR, but which is linked to the 7TM region by a GPCR autoproteolysis-inducing (GAIN) domain [10] containing a GPCR proteolysis site (GPS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f550b84d01ca30f164d3d83f1cb9cbe
https://doi.org/10.2218/gtopdb/f17/2023.1
https://doi.org/10.2218/gtopdb/f17/2023.1
Autor:
Marleen Würfel, Katrin Horn, Diana Le Duc, Akhil Velluva, Carola Marzi, Harald Grallert, Nele Friedrich, Maik Pietzner, Uwe Völker, Henry Völzke, Emma Ahlqvist, Dina Mansour Aly, Tiinamaija Tuomi, Ronny Baber, Jürgen Kratzsch, Joachim Thiery, Berend Isermann, Markus Löffler, Nora Klöting, Matthias Blüher, Michael Stumvoll, John T. Heiker, Anke Tönjes, Markus Scholz, Peter Kovacs, Jana Breitfeld
Publikováno v:
Diabetologie und Stoffwechsel.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3e897a898505c7ed79db3a456997c71
https://doi.org/10.1055/s-0043-1767883
https://doi.org/10.1055/s-0043-1767883
Autor:
Tobias Bartolomaeus, Alejandro Leal, Katharina Schoner, Ilona Krey, Rami Abou Jamra, Luis Bermúdez-Guzmán, Steffen Syrbe, Helga Rehder, Susanna Schubert, Christian Roth, Sonja Neuser, Annemarie Schwan, Margit Plassmann, Maximilian Radtke, Diana Le Duc, Stefan Rohde, Bernt Popp, Jan Henje Döring
Publikováno v:
European Journal of Human Genetics
Biallelic PNKP variants cause heterogeneous disorders ranging from neurodevelopmental disorder with microcephaly/seizures to adult-onset Charcot–Marie–Tooth disease. To date, only postnatal descriptions exist. We present the first prenatal diagno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186f10532342877c5874b9df609f229b
https://doi.org/10.1038/s41431-021-00982-y
https://doi.org/10.1038/s41431-021-00982-y