Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Diana, Dudziak"'
Autor:
Chunguang Liang, Silvia Spoerl, Yin Xiao, Katharina M. Habenicht, Sigrun S. Haeusl, Isabel Sandner, Julia Winkler, Nicholas Strieder, Rüdiger Eder, Hanna Stanewsky, Christoph Alexiou, Diana Dudziak, Andreas Rosenwald, Matthias Edinger, Michael Rehli, Petra Hoffmann, Thomas H. Winkler, Friederike Berberich-Siebelt
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract In clinical situations, peripheral blood accessible CD3+CD4+CXCR5+ T-follicular helper (TFH) cells may have to serve as a surrogate indicator for dysregulated germinal center responses in tissues. To determine the heterogeneity of TFH cells
Externí odkaz:
https://doaj.org/article/7c0d3bc23f4c4d5f842af48b76085e66
Autor:
Lukas Amon, Anna Seichter, Damir Vurnek, Giorgi Tchitashvili, Isabel Heß, Lukas Heger, Christian H.K. Lehmann, Diana Dudziak
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103151- (2024)
Summary: Dendritic cells (DCs) populate nearly all tissues and represent the central orchestrators of immunity. Here, we present a protocol for the mild but efficient preparation of single-cell suspensions from multiple murine tissues and the downstr
Externí odkaz:
https://doaj.org/article/d68500fdc6f6488fa5d9dd40c0c3d5dd
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/3836affbda054762889a7cf5098ce026
Autor:
Lukas Heger, Gordon F. Heidkamp, Lukas Amon, Falk Nimmerjahn, Tobias Bäuerle, Andreas Maier, Ramona Erber, Arndt Hartmann, Carolin C. Hack, Matthias Ruebner, Hanna Huebner, Peter Fasching, Matthias W. Beckmann, Diana Dudziak
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTBreast cancer is the most common malignancy in women worldwide and a highly heterogeneous disease. Four different subtypes are described that differ in the expression of hormone receptors as well as the growth factor receptor HER2. Treatment
Externí odkaz:
https://doaj.org/article/2fea48d7018642c3a2bf91299e025a26
Autor:
Xinyi Wei, MSc, Sabine Weber, MD, Decheng Yin, MSc, Ida Allabauer, Tilman Jobst-Schwan, MD, Michael Wiesener, MD, Mario Schiffer, MD, Diana Dudziak, PhD, Christian H. K. Lehmann, PhD, Joachim Woelfle, MD, Andre Hoerning, MD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1666 (2024)
Background. The mammalian target of rapamycin inhibitor (mTORi) therapy after kidney transplantation is solely monitored pharmacokinetically, not necessarily reflecting PI3K-Akt-mTOR pathway blockade efficacy leading to potential under-or overimmunos
Externí odkaz:
https://doaj.org/article/701e3fa629a94ad99b283dc1d0ebf8a1
Autor:
Lukas Amon, Anna Seichter, Damir Vurnek, Lukas Heger, Lukas Lächele, Nounagnon Romaric Tochoedo, Tomasz Kaszubowski, Lukas Hatscher, Anna Baranska, Giorgi Tchitashvili, Falk Nimmerjahn, Christian Herbert Kurt Lehmann, Diana Dudziak
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113949- (2024)
Summary: Over the last decade, multiple studies have investigated the heterogeneity of murine conventional dendritic cells type 2 (cDC2s). However, their phenotypic similarity with monocytes and macrophages renders their clear identification challeng
Externí odkaz:
https://doaj.org/article/1552a7ba29174d2fa640a08cca50f5d1
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/580a54200d454cba918543f6338e2fbc
Autor:
Jian Fu, Christian H. K. Lehmann, Xinning Wang, Mandy Wahlbuhl, Ida Allabauer, Benjamin Wilde, Lukas Amon, Sebastian Dolff, Robert Cesnjevar, Andreas Kribben, Joachim Woelfle, Wolfgang Rascher, Peter F. Hoyer, Diana Dudziak, Oliver Witzke, André Hoerning
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Allograft-specific regulatory T cells (Treg cells) are crucial for long-term graft acceptance after transplantation. Although adoptive Treg cell transfer has been proposed, major challenges include graft-specificity and stability. Thus, ther
Externí odkaz:
https://doaj.org/article/aed570743c9f4d9fb446c26967b40fc2
Autor:
Carmen Reitinger, Andrea Ipsen-Escobedo, Chiara Hornung, Lukas Heger, Diana Dudziak, Anja Lux, Falk Nimmerjahn
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Checkpoint control and immunomodulatory antibodies have become important tools for modulating tumor or self-reactive immune responses. A major issue preventing to make full use of the potential of these immunomodulatory antibodies are the severe side
Externí odkaz:
https://doaj.org/article/b941d04086cd4943a435bb421dd4a8d8
Autor:
Nikos E. Papaioannou, Natallia Salei, Stephan Rambichler, Kaushikk Ravi, Jelena Popovic, Vanessa Küntzel, Christian H. K. Lehmann, Remi Fiancette, Johanna Salvermoser, Dominika W. Gajdasik, Ramona Mettler, Denise Messerer, Joana Carrelha, Caspar Ohnmacht, Dirk Haller, Ralf Stumm, Tobias Straub, Sten Eirik W. Jacobsen, Christian Schulz, David R. Withers, Gunnar Schotta, Diana Dudziak, Barbara U. Schraml
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Type 2 conventional dendritic cells (cDC2) are important immune activators in adults, but their development and functions at the neonatal stage remain unclear. Here the authors show, using fate-mapping and single-cell RNA sequencing, that neonatal cD
Externí odkaz:
https://doaj.org/article/41e3849697dd487fb5c3e7640b8e444b