Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Diah S. Bramono"'
Autor:
Saminathan S. Nathan, Bina Rai, James Hoi Po Hui, J.L.J. Lee, Diah S. Bramono, Victor Nurcombe, Hee-Kit Wong, Ling Ling, Sadasivam Murali, Simon M. Cool, Christian Dombrowski, Simon F.R. Hinkley, Zophia X.H. Lim, Tracey J. Bell
Publikováno v:
Biomaterials. 34:5594-5605
Bone morphogenetic protein (BMP)-2 is a potent bone healing compound produced at sites of bone trauma. Here we present a therapeutic strategy to harness the activity of endogenously produced BMP-2 by delivery of an affinity-matched heparan sulfate (H
Autor:
Ling Ling, Sadasivam Murali, Gary S. Stein, Bina Rai, Andre J. van Wijnen, Diah S. Bramono, Wei Theng Poh, Zophia X.H. Lim, Victor Nurcombe, Simon M. Cool
Publikováno v:
Bone. 50:954-964
Lowering the efficacious dose of bone morphogenetic protein-2 (BMP-2) for the repair of critical-sized bone defects is highly desirable, as supra-physiological amounts of BMP-2 have an increased risk of side effects and a greater economic burden for
Publikováno v:
Pharmaceutical Research. 28:1385-1394
In order to address cell dose limitations associated with the use of cord blood hematopoietic stem cell (HSC) transplantation, we explored the effect of bone marrow stroma-derived heparan sulfate (HS) on the ex vivo expansion of HSCs.Heparan sulfate
Publikováno v:
Tissue Engineering Part A. 14:1161-1172
Application of stimuli in sequence to developing cultures in vitro offers the potential to intricately direct cell development and differentiation by following the template of native tissue behavior. We hypothesize that administration of mechanical s
Autor:
David L. Kaplan, Ivan Martin, Paul P. Weitzel, Caroline M. Jakuba, Herman Chernoff, Frank Diaz, Vladimir Volloch, Diah S. Bramono, Jaipal S. Gandhi, Gregory H. Altman, John C. Richmond
Publikováno v:
Connective Tissue Research. 46:53-65
An improved understanding of cellular responses during normal anterior cruciate ligament (ACL) function or repair is essential for clinical assessments, understanding ligament biology, and the implementation of tissue engineering strategies. The pres
Autor:
Gregory H. Altman, Gordana Vunjak-Novakovic, Jodie E. Moreau, Herman Chernoff, John C. Richmond, Jingsong Chen, David L. Kaplan, Vladimir Volloch, Diah S. Bramono
Publikováno v:
Journal of Orthopaedic Research. 23:164-174
Utilizing a two-dimensional tissue culture plastic screening system and a fractional factorial design, specific media formulations and growth factor combinations were determined that support human bone marrow stromal cell (BMSC) differentiation towar
Publikováno v:
Clinical Orthopaedics & Related Research. 428:272-285
Imbalance in the expression of matrix metalloproteinases and their inhibitors contribute considerably to abnormal connective tissue degradation prevalent in various orthopaedic joint diseases such as rheumatoid arthritis and osteoarthritis. Matrix me
Autor:
Heather E. Boepple, Rebecca L. Horan, Gregory H. Altman, Q. Simmons, Jingsong Chen, J. R. L. Stanley, Diah S. Bramono
Publikováno v:
Hernia : the journal of hernias and abdominal wall surgery. 13(2)
The patient’s own repair of a body wall defect would be enhanced by a mechanically robust, physically tailorable, bioresorbable mesh scaffold that: (1) supports rapid host tissue ingrowth and development, while (2) reducing the complications associ
Autor:
Ivan Toponarski, Jingsong Chen, Diah S. Bramono, Enrico Mortarino, Quincey Simmons, Heather E. Boepple, Jason S. Prudom, Adam L. Collette, Gregory H. Altman, Rebecca L. Horan
Publikováno v:
Journal of the American College of Surgeons. 205:S53-S54
Autor:
Laura R. Geuss, Jodie E. Moreau, Yongzhong Wang, Gregory H. Altman, Vladimir Volloch, Diah S. Bramono, Adam L. Collette, Rebecca L. Horan, Jingsong Chen
Publikováno v:
Tissue Engineering. :061017080728005
To evaluate the appropriate time frame for applying mechanical stimuli to induce mesenchymal stromal cell (MSC) differentiation for ligament tissue engineering, developmental cell phenotypes were monitored during a period of in vitro culture. MSCs we