Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Diacylglycerol kinase zeta"'
Akademický článek
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Autor:
Junchen Gu, Cindy Wang, Carolyn Cao, Jinwen Huang, Sandra Holzhauer, Heshani Desilva, Erin M. Wesley, Douglas B. Evans, Joseph Benci, Michael Wichroski, Susan Wee, Matthew J. Riese
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Two isoforms of diacylglycerol kinases (DGKs), DGKα and DGKζ, are primarily responsible for terminating DAG-mediated activation of Ras and PKCθ pathways in T cells. A direct comparison of tumor growth between mice lacking each isoform has not been
Externí odkaz:
https://doaj.org/article/5d3031950b2e4b1aa8390e28fad5c75f
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 1517-1529 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 1517-1529 (2021)
Diacylglycerol kinase zeta (DGKZ) participates in cancer progression. Here, the current work aims to identify the functional role of DGKZ in cervical cancer (CC). DGKZ expression in cervical cancer tissues and paired adjacent normal cervical tissues
Autor:
Nathaniel L. Elsen, Sujatha M. Gopalakrishnan, David Chang-Yen, Andrew J. Radosevich, James W. Sawicki, Jon D. Williams, Fan Pu, Nari Talaty
Publikováno v:
Analytical Chemistry. 93:6792-6800
Mass spectrometry (MS) can provide high sensitivity and specificity for biochemical assays without the requirement of labels, eliminating the risk of assay interference. However, its use had been limited to lower-throughput assays due to the need for
Autor:
Douglas B Evans, Benci Joseph L, Junchen Gu, Michael Wichroski, Susan Wee, Carolyn Cao, Matthew J. Riese, Erin Wesley, Sandra L. Holzhauer, Heshani Desilva, Cindy Wang, Jinwen Huang
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Two isoforms of diacylglycerol kinases (DGKs), DGKα and DGKζ, are primarily responsible for terminating DAG-mediated activation of Ras and PKCθ pathways in T cells. A direct comparison of tumor growth between mice lacking each isoform has not been
Publikováno v:
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 38:175-178
The diacylglycerol kinases (DGKs) catalyze the phosphorylation of the cell membrane lipid diacylglycerol (DG), which is important in lipid biochemistry and signal transduction into phosphatidic acid. DG-mediated signal transduction downstream of the
Autor:
Li Liu, Changlian Lu, Peng Zhang, Jihong Meng, Yeling Tang, Wangxian Gu, Zhifang Yang, Xuefeng Gu, Guoqing Wan, Cuiting Jin, Jinhong Li, Nian-Hong Chen, Bing Chen
Publikováno v:
International Journal of Biological Sciences
Glioblastoma is one of the most malignant brain cancers in adults, and it is a fatal disease because of its untimely pathogenetic location detection, infiltrative growth, and unfavorable prognosis. Unfortunately, multimodal treatment with maximal saf
Autor:
Jing Li, Shuang Li, Chaohua Tang, Tengfei Zhan, Qingyu Zhao, Kai Zhang, Xiaoqing Guo, Junmin Zhang, Yunsheng Han
Publikováno v:
Redox Biology
Redox Biology, Vol 36, Iss, Pp 101519-(2020)
Redox Biology, Vol 36, Iss, Pp 101519-(2020)
Selenium (Se) intake disequilibrium is associated with many human diseases (e.g., Keshan disease and type 2 diabetes). To understand the mechanism of Se deficiency-induced hepatic pathogenesis, a pure line pig model was established by feeding a diet
Autor:
Matthew J. Riese, Gang Xin, Bryon D. Johnson, Erin Wesley, Weiguo Cui, Subramaniam Malarkannan, Donna McAllister, Michael B. Dwinell, Debra K. Newman
Publikováno v:
ImmunoHorizons. 2:107-118
Targeting negative regulators downstream of the TCR represents a novel strategy to improve cancer immunotherapy. Two proteins that serve as critical inhibitory regulators downstream of the TCR are diacylglycerol kinase ζ (DGKζ), a regulator of Ras
Akademický článek
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