Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice

Autor: Friedrich Grimminger, Stefan Offermanns, Florian Veit, Beate Fuchs, Werner Seeger, Oleg Pak, Hermann Kalwa, Ajay M. Shah, Alison C. Brewer, Thomas Gudermann, Michael Mederos y Schnitzler, Norbert Weissmann, Alexander Dietrich, Karl-Heinz Krause, Akylbek Sydykov, Ralph T. Schermuly, Ursula Storch, Hossein Ardeschir Ghofrani, Harald H.H.W. Schmidt, Ralf P. Brandes, Marc Freichel, Marcel Meissner

Publikováno v: Nature Communications, Vol. 3 (2012) P. 649
Nature Communications, 3. Nature Publishing Group
Nature communications
Nature Communications

Lung ischaemia–reperfusion-induced oedema (LIRE) is a life-threatening condition that causes pulmonary oedema induced by endothelial dysfunction. Here we show that lungs from mice lacking nicotinamide adenine dinucleotide phosphate (NADPH) oxidase

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https://archive-ouverte.unige.ch/unige:32460