Zobrazeno 1 - 10
of 4 053
pro vyhledávání: '"Diabetic wound"'
Publikováno v:
Bioactive Materials, Vol 41, Iss , Pp 523-536 (2024)
Chronic bioenergetic imbalances and inflammation caused by hyperglycemia are obstacles that delay diabetic wound healing. However, it is difficult to directly deliver energy and metabolites to regulate intracellular energy metabolism using biomateria
Externí odkaz:
https://doaj.org/article/bbb66e914d8346e386e073824739fbe2
Autor:
May Barakat, Chen Han, Lin Chen, Brian P. David, Junhe Shi, Angela Xu, Kornelia J. Skowron, Tatum Johnson, Reginald A. Woods, Aparna Ankireddy, Sekhar P. Reddy, Terry W. Moore, Luisa A. DiPietro
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract The transcription factor NRF2 plays an important role in many biological processes and is a promising therapeutic target for many disease states. NRF2 is highly expressed in the skin and is known to play a critical role in diabetic wound hea
Externí odkaz:
https://doaj.org/article/2bc85f20295a4c28a88558c8a966f094
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 7373-7388 (2024)
Wenjuan Yi,1 Qionglin Bao,2 Dingkun Xu,3 Chenyu Long,1 Ruixin Fang,1 Wenlin Cheng,4 Jiquan Song,1 Huiting Feng1 1Department of Dermatology, Zhongnan Hospital of Wuhan University, Wuhan, People’s Republic of China; 2Wound Repair Center, Chronic Woun
Externí odkaz:
https://doaj.org/article/e540d6b27fb24147b014bf877589d9a7
Autor:
Wonmoon Song, Young Hwan Choi, Young Gi Moon, Changyub Lee, M. Nivedhitha Sundaram, Nathaniel S. Hwang
Publikováno v:
Bioactive Materials, Vol 40, Iss , Pp 582-596 (2024)
Wounds, characterized by the disruption of the continuity of body tissues resulting from external trauma, manifest in diverse types and locations. Although numerous wound dressings are available for various wound scenarios, it remains challenging to
Externí odkaz:
https://doaj.org/article/0ca7edc57d3d4aca8e26b27e5e9119a0
Autor:
Hai Zhou, Lianglong Chen, Chaoyang Huang, Ziwei Jiang, Huihui Zhang, Xiaoyang Liu, Fengyi Zhu, Qiulan Wen, Pengwei Shi, Kun Liu, Lei Yang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Improper management of diabetic wound effusion and disruption of the endogenous electric field can lead to passive healing of damaged tissue, affecting the process of tissue cascade repair. This study developed an extracellular matrix sponge
Externí odkaz:
https://doaj.org/article/a3aea207ee0b4afd8541af9e82e8f999
Publikováno v:
Engineered Regeneration, Vol 5, Iss 3, Pp 421-431 (2024)
Conditioned medium (CM) derived from human umbilical cord-mesenchymal stem cells (hUC-MSCs) which contains numerous amounts of growth factors, has demonstrated potential in treatment of diabetic wounds. However, for practical application, a biodegrad
Externí odkaz:
https://doaj.org/article/27a0ddd233db4c1e96912774512de373
Publikováno v:
Bioactive Materials, Vol 39, Iss , Pp 302-316 (2024)
Diabetic wounds, characterized by prolonged inflammation and impaired vascularization, are a serious complication of diabetes. This study aimed to design a gelatin methacrylate (GelMA) hydrogel for the sustained release of netrin-1 and evaluate its p
Externí odkaz:
https://doaj.org/article/0102443875474cc2916125767b24068c
Autor:
Xuelian Zhang, Hang Li, Yang Liu, Jie Yu, Pengfei Zhang, Peiling Yu, Yuhao Liu, Suyi Jia, Lijuan Ling, Peng Li, Lei Li, Yueyao Wang, Tengxiao Huang, Gaoxin Jin, Yunpeng Zhao, Guoli Ma, Qinghao Yuan, Lei Zhu, Zhiyue Zhang, Hao Li, Weiwei Li
Publikováno v:
Bioactive Materials, Vol 44, Iss , Pp 269-282 (2025)
Diabetic ulcers (DUs) are persistent and challenging complications of diabetes. The consequences of DUs include a decline in functional status, increased risk of infection, hospitalization, and even death. Our study revealed a significant decrease in
Externí odkaz:
https://doaj.org/article/aa02b0680f2c43a7806d53cb1570aad0
Autor:
Yanpeng Cao, Bei Chen, Qixing Liu, Yiyang Mao, Yusheng He, Xiaoren Liu, Xin Zhao, Yaowu Chen, Xiying Li, Yabei Li, Liang Liu, Chengwu Guo, Shiyu Liu, Fenghua Tan, Hongbin Lu, Jun Liu, Can Chen
Publikováno v:
Bioactive Materials, Vol 42, Iss , Pp 32-51 (2024)
Due to overactive inflammation and hindered angiogenesis, self-healing of diabetic wounds (DW) remains challenging in the clinic. Platelet-derived exosomes (PLT-Exos), a novel exosome capable of anti-inflammation and pro-angiogenesis, show great pote
Externí odkaz:
https://doaj.org/article/f456cf92f5944efca7b50dd738990867
Publikováno v:
Regenerative Therapy, Vol 27, Iss , Pp 342-353 (2024)
Background: One of the key obstacles to the healing of diabetic wound is the persistence of active inflammation. We previously demonstrated the potential of cell-free fat extract (CEFFE) to promote the healing of diabetic wounds, and annexin A5 (A5)
Externí odkaz:
https://doaj.org/article/f5d7e08c6f5b403f9b87c5046e5a29fe