Zobrazeno 1 - 10 of 94 pro vyhledávání: '"Diabetes and Endocrinology/Endocrinology"'
1
Serum IGF-1 affects skeletal acquisition in a temporal and compartment-specific manner
Autor: Hui Sun, Sebastien Elis, Shoshana Yakar, Yingjie Wu, Hayden William Courtland, Karl J. Jepsen, Clifford J. Rosen
Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2011, 6 (3), pp.1-10. ⟨10.1371/journal.pone.0014762⟩
PLoS ONE, Vol 6, Iss 3, p e14762 (2011)
Plos One 3 (6), 1-10. (2011)
International audience; Insulin-like growth factor-1 (IGF-1) plays a critical role in the development of the growing skeleton by establishing both longitudinal and transverse bone accrual. IGF-1 has also been implicated in the maintenance of bone mas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4284a3105b73055cc848df73611b04af
https://hal.inrae.fr/hal-02646360/document
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2
Glucocorticoid-mediated inhibition of angiogenic changes in human endothelial cells is not caused by reductions in cell proliferation or migration
Autor: Sadaf Ali, Brian R. Walker, Margarete M. S. Heck, Kathryn M. Marshall, James J. Logie, Patrick W. F. Hadoke
Publikováno v: PLoS ONE, Vol 5, Iss 12, p e14476 (2010)
PLoS ONE
Logie, J J, Ali, S, Marshall, K M, Heck, M M S, Walker, B R & Hadoke, P W F 2010, ' Glucocorticoid-Mediated Inhibition of Angiogenic Changes in Human Endothelial Cells Is Not Caused by Reductions in Cell Proliferation or Migration ', PLoS ONE, vol. 5, no. 12, e14476 . https://doi.org/10.1371/journal.pone.0014476
Background Glucocorticoid-mediated inhibition of angiogenesis is important in physiology, pathophysiology and therapy. However, the mechanisms through which glucocorticoids inhibit growth of new blood vessels have not been established. This study add
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13de0548c0d4f5834389bc247ecdcc8a
http://europepmc.org/articles/PMC3013101?pdf=render
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3
Maternal environmental contribution to adult sensitivity and resistance to obesity in Long Evans rats
Autor: Aron Weller, Mariana Schroeder, Timothy H. Moran, Liat Shbiro
Publikováno v: PLoS ONE, Vol 5, Iss 11, p e13825 (2010)
PLoS ONE
Background The OLETF rat is an animal model of early onset hyperphagia induced obesity, presenting multiple pre-obese characteristics during the suckling period. In the present study, we used a cross-fostering strategy to assess whether interactions
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1716f956b545c142ba02dcf10304c8df
http://europepmc.org/articles/PMC2972212?pdf=render
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4
IGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells
Autor: Lucia Briatore, Renzo Cordera, Meriem Hamoudane, Mario Passalacqua, Davide Maggi, Paola Contini, Barbara Salani, Sara Maffioli
Publikováno v: PLoS ONE, Vol 5, Iss 11, p e14157 (2010)
PLoS ONE
Background: Insulin-like growth factor-I receptor (IGF-IR) is a tyrosine kinase receptor (RTK) associated with caveolae, invaginations of the plasma membrane that regulate vesicular transport, endocytosis and intracellular signaling. IGF-IR internali
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51eaf69b01fd5f2122eb90e101719e28
http://europepmc.org/articles/PMC2994771?pdf=render
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5
Adipokine Pattern in Subjects with Impaired Fasting Glucose and Impaired Glucose Tolerance in Comparison to Normal Glucose Tolerance and Diabetes
Autor: Michael Stumvoll, Matthias Blüher, Mathias Fasshauer, Jürgen Kratzsch, Anke Tönjes
Publikováno v: PLoS ONE
PLoS ONE, Vol 5, Iss 11, p e13911 (2010)
Aim Altered adipokine serum concentrations early reflect impaired adipose tissue function in obese patients with type 2 diabetes (T2D). It is not entirely clear whether these adipokine alterations are already present in prediabetic states and so far
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a177b390dec23ae0a22d26c44f429c32
http://europepmc.org/articles/PMC2976690
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6
Differential Impact of Tetratricopeptide Repeat Proteins on the Steroid Hormone Receptors
Autor: Jan-Philip Schülke, Gabriela Monika Wochnik, Isabelle Lang-Rollin, Nils Christian Gassen, Regina Theresia Knapp, Barbara Berning, Alexander Yassouridis, Theo Rein
Publikováno v: PLoS ONE
PLoS ONE, Vol 5, Iss 7, p e11717 (2010)
BackgroundTetratricopeptide repeat (TPR) motif containing co-chaperones of the chaperone Hsp90 are considered control modules that govern activity and specificity of this central folding platform. Steroid receptors are paradigm clients of Hsp90. The
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d06285b1fb87568fede2cd440abdb43c
http://europepmc.org/articles/PMC2908686
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7
Disruption of PTH receptor 1 in T cells protects against PTH-induced bone loss
Autor: Brahmchetna Bedi, Roberto Pacifici, M. Neale Weitzmann, Jonathan Adams, Henry M. Kronenberg, Hesham M. Tawfeek, Tatsuya Kobayashi, Jau-Yi Li
Publikováno v: PLoS ONE
PLoS ONE, Vol 5, Iss 8, p e12290 (2010)
Background Hyperparathyroidism in humans and continuous parathyroid hormone (cPTH) treatment in mice cause bone loss by regulating the production of RANKL and OPG by stromal cells (SCs) and osteoblasts (OBs). Recently, it has been reported that T cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391a13ed9f9205a806025d42562fc6ce
https://pubmed.ncbi.nlm.nih.gov/20808842
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8
NPY Neuron-Specific Y2 Receptors Regulate Adipose Tissue and Trabecular Bone but Not Cortical Bone Homeostasis in Mice
Autor: Ji-Ming Ye, Paul A. Baldock, Aygul Aljanova, Natalie F. Mitchell, Ronaldo F. Enriquez, Yan-Chuan Shi, Amy D. Nguyen, Sabrina J. Riepler, Lesley Castillo, Shu Lin, Laurence Macia, Herbert Herzog, Iris P. L. Wong, Ernie Yulyaningsih, Amanda Sainsbury, Lei Zhang
Publikováno v: PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11361 (2010)
BACKGROUND: Y2 receptor signalling is known to be important in neuropeptide Y (NPY)-mediated effects on energy homeostasis and bone physiology. Y2 receptors are located post-synaptically as well as acting as auto receptors on NPY-expressing neurons,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::334f28fcf792da9992ea71c14d935cbe
http://europepmc.org/articles/PMC2894044
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9
Extranuclear estrogen receptors mediate the neuroprotective effects of estrogen in the rat hippocampus
Autor: Yi Dong Zhang, Cai Feng Zhou, Ruimin Wang, Li Cai Yang, Quanguang Zhang, Fang Yang, Darrell W. Brann
Publikováno v: PLoS ONE, Vol 5, Iss 5, p e9851 (2010)
PLoS ONE
Background 17β-estradiol (E2) has been implicated to exert neuroprotective effects in the brain following cerebral ischemia. Classically, E2 is thought to exert its effects via genomic signaling mediated by interaction with nuclear estrogen receptor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1500259ce5928641d4dd9d76b740d8ba
http://europepmc.org/articles/PMC2866326?pdf=render
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10
Metabolic state alters economic decision making under risk in humans
Autor: Mkael Symmonds, Raymond J. Dolan, Rachel L. Batterham, Julian J. Emmanuel, Megan E. Drew
Publikováno v: PLoS ONE
PLoS ONE, Vol 5, Iss 6, p e11090 (2010)
BACKGROUND: Animals' attitudes to risk are profoundly influenced by metabolic state (hunger and baseline energy stores). Specifically, animals often express a preference for risky (more variable) food sources when below a metabolic reference point (h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e81f5ad35dea91c1eab8a249e32a57
https://pubmed.ncbi.nlm.nih.gov/20585383
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