Functional and morphological renal changes in a Göttingen Minipig model of obesity-related and diabetic nephropathy

Autor: Christoffersen, Berit Østergaard, Kristensen, Camilla Aarup, Lindgaard, Rikke, Kirk, Rikke Kaae, Viuff, Birgitte Martine, Kvist, Peter Helding, Pedersen, Henrik Duelund, Ludvigsen, Trine Pagh, Skovgaard, Tine, Fels, Johannes Josef, Martinussen, Torben, Christiansen, Liselotte Bruun, Cirera, Susanna, Olsen, Lisbeth Høier

Publikováno v: Christoffersen, B Ø, Kristensen, C A, Lindgaard, R, Kirk, R K, Viuff, B M, Kvist, P H, Pedersen, H D, Ludvigsen, T P, Skovgaard, T, Fels, J J, Martinussen, T, Christiansen, L B, Cirera, S & Olsen, L H 2023, ' Functional and morphological renal changes in a Göttingen Minipig model of obesity-related and diabetic nephropathy ', Scientific Reports, vol. 13, 6017 . https://doi.org/10.1038/s41598-023-32674-6

Obesity-related glomerulopathy and diabetic nephropathy (DN) are serious complications to metabolic syndrome and diabetes. The purpose was to study effects of a fat, fructose and cholesterol-rich (FFC) diet with and without salt in order to induce hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9446f97cb45623a5b840fed07f9251e
https://doi.org/10.1038/s41598-023-32674-6

Vascular Calcification and not Arrhythmia in Idiopathic Atrial Fibrillation Associates with Sex Differences in Diabetic Microvascular Injury miRNA Profiles

Autor: Bob Weijs, Jacques M.G.J. Duijs, Joachim E. Wildberger, Justin G.L.M. Luermans, Uli Schotten, Harry J.G.M. Crijns, Elton A. M. P. Dudink, Barend W. Florijn, Anton Jan van Zonneveld, Leon J. Schurgers, Frederique Ecm Peeters, Roel Bijkerk

Publikováno v: MicroRNA (Shāriqah, United Arab Emirates), 8(2), 127-134. Bentham Science Publishers

Background: Atrial Fibrillation (AF) in patients without concomitant cardiovascular pathophysiological disease, is called idiopathic Atrial Fibrillation (iAF). Nonetheless, iAF patients have often times subclinical coronary (micro) vascular dysfuncti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9222daa6eafa4e18e345b998b1222c01
https://doi.org/10.2174/2211536608666181122125208

Roles of Noncoding RNAs in Islet Biology

Autor: Claudiane Guay, Adriana Rodriguez-Trejo, Cécile Jacovetti, Romano Regazzi, Kejing Wu, Mustafa Bilal Bayazit, Flora Brozzi

Publikováno v: Comprehensive Physiology
Comprehensive Physiology, vol. 10, no. 3, pp. 893-932

The discovery that most mammalian genome sequences are transcribed to ribonucleic acids (RNA) has revolutionized our understanding of the mechanisms governing key cellular processes and of the causes of human diseases, including diabetes mellitus. Pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d824b6d962f9faa744d9b48bed4b79
https://pubmed.ncbi.nlm.nih.gov/32941685

Exosomes as new players in metabolic organ cross-talk

Autor: Guay, C., Regazzi, R.

Publikováno v: Diabetes, obesity & metabolism, vol. 19 Suppl 1, pp. 137-146

Blood glucose homeostasis requires a constant communication between insulin-secreting and insulin-sensitive cells. A wide variety of circulating factors, including hormones, cytokines and chemokines work together to orchestrate the systemic response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1900::c20028d14e9ebce5443336d9a20cc3b3
https://serval.unil.ch/notice/serval:BIB_67B77266C639

Upper gastrointestinal sensory-motor dysfunction in diabetes mellitus

Autor: Jens Brøndum Frøkjær, Jingbo Zhao, Asbjørn Mohr Drewes, Niels Ejskjaer

Publikováno v: Zhao, J, Frøkjær, J B, Drewes, A M & Ejskjaer, N 2006, ' Upper gastrointestinal sensory-motor dysfunction in diabetes mellitus ', World Journal of Gastroenterology, vol. 12, no. 18, pp. 2846-2857 . https://doi.org/10.3748/wjg.v12.i18.2846, https://doi.org/10.3748/wjg.v12.i18.2846
Aarhus University
Aalborg University
Zhao, J, Frøkjær, J B, Drewes, A M & Ejskjær, N 2006, ' Upper gastrointestinal sensory-motor dysfunction in diabetes mellitus ', World Journal of Gastroenterology, vol. 12, no. 18, pp. 2846-2857 .
Zhao, J, Frøkjær, J, Drewes, A M & Ejskjær, N 2008, ' Upper gastrointestinal sensory-motor dysfunction in diabetes mellitus ', Medical Recapitulate (Chinese), bind 23, s. 3537-3542 .

Gastrointestinal (GI) sensory-motor abnormalities are common in patients with diabetes mellitus and may involve any part of the GI tract. Abnormalities are frequently sub-clinical, and fortunately only rarely do severe and life-threatening problems o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5be0b7f0da60de87765b6432c4649a7
https://vbn.aau.dk/da/publications/c3a5dd00-cc87-11db-9e19-000ea68e967b